Search Result

Results for "

interleukin-17

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Interleukin Related (15) mRNA (2)
By Research Areas:	Cancer (2) Infection (2) Inflammation/Immunology (16)
Oligonucleotides:	mRNA (2) Interleukin & Receptors (2)

Inhibitors & Agonists

Peptides

MCE Kits

Inhibitory Antibodies

Recombinant Proteins

Antibodies

Oligonucleotides

Targets Recommended: Interleukin Related IRAK Itk

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-P9925

Brodalumab 4 Publications Verification AMG 827; KHK4827	Interleukin Related	Inflammation/Immunology
Brodalumab (AMG 827) is a human anti-interleukin-17-receptor IgG2 monoclonal antibody that can be used for the research of moderate-to-severe plaque psoriasis and rheumatoid arthritis .

HY-153780

Navepdekinra DC-806; LY4100504; S-011806	Interleukin Related	Inflammation/Immunology
Navepdekinra (DC-806) is an orally active, potent interleukin-17A (IL-17A) inhibitor (IC₅₀ = 10.81 nM). Navepdekinra disrupts the IL-17A protein-receptor interaction, suppressing the downstream pro-inflammatory signaling pathway. Navepdekinra inhibits arthritis in a collage-induced arthritis (CIA) rat model. Navepdekinra can be used for psoriasis, psoriatic arthritis, and ankylosing spondylitis .

HY-P9927A

Secukinumab (Anti-Human IL-17A) 1 Publications Verification	Interleukin Related	Inflammation/Immunology Cancer
Secukinumab (Anti-Human IL-17A) is a fully human anti-interleukin-17A monoclonal antibody. Anti-Human IL-17A can be used for research in psoriasis pathogenesis .

HY-P991266

SM-17	Interleukin Related	Inflammation/Immunology
SM-17 is a humanized monoclonal antibody inhibitor targeting interleukin 25 (IL-25) and interleukin-17 receptor B (IL17RB). SM-17 is promising for research of immune system diseases .

HY-P99754

Netakimab BCD-085	Interleukin Related	Infection Inflammation/Immunology
Netakimab (BCD-085) is a humanized IgG1κ monoclonal anti-IL-17 antibody that binds to and blocks *IL-17* and *IL-17A* activity, including reduction of downstream IL-6 production. Netakimab can be used for the research of moderate-to-severe plaque psoriasis, ankylosing spondylitis, and COVID-19 with cytokine release syndrome . Recommend Isotype Controls: Human IgG1 kappa, Isotype Control (HY-P99001).

HY-P99335

Vunakizumab Anti-Human IL17A Recombinant Antibody; SHR-1314	Interleukin Related	Inflammation/Immunology
Vunakizumab (Anti-Human IL17A Recombinant Antibody) is a recombinant human IgGκ monoclonal antibody and an *Interleukin-17A* (IL-17A) inhibitor. Vunakizumab binds to IL-17A to inhibit downstream cytokines and block inflammatory signaling. Vunakizumab can be used for the research of chronic plaque psoriasis and ankylosing spondylitis .

HY-P99515

Xeligekimab GR 1501	Interleukin Related	Inflammation/Immunology
Xeligekimab (GR 1501) is an anti-human interleukin 17A (IL-17A) humanized monoclonal antibody. Xeligekimab inhibits the pro-inflammatory cascade. Xeligekimab can be used for the research of inflammatory disease, such as radiographic axial spondyloarthritis .

HY-P3450

Erepdekinra	Interleukin Related	Inflammation/Immunology
Erepdekinra is an interleukin-17A (IL-17A) receptor antagonist .

HY-158159

IL17A-IN-1	Interleukin Related	Inflammation/Immunology Cancer
IL17A-IN-1 (compound 72) is an orally active *Interleukin 17A* inhibitor. IL17A-IN-1 can be used in the study of inflammatory and autoimmune diseases (plaque psoriasis, psoriatic arthritis, and ankylosing spondylitis, etc.), as well as cancer .

HY-174632

Human IL17RA mRNA	mRNA	Inflammation/Immunology
Human IL17RA mRNA encodes the human interleukin 17 receptor subunit alpha (IL17RA) protein, a ubiquitous type I membrane glycoprotein that binds with low affinity to interleukin 17A. Interleukin 17A and its receptor play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis.

HY-P991260

CNTO-6785	Interleukin Related	Infection
CNTO-6785 is a humanized monoclonal antibody inhibitor targeting interleukin-17A (IL-17A). CNTO-6785 is promising for research of chronic obstructive pulmonary disease (COPD) .

HY-P991263

SCH-900117	Interleukin Related	Inflammation/Immunology
SCH-900117 is a humanized monoclonal antibody inhibitor targeting interleukin-17A (IL-17A). SCH-900117 is promising for research of autoimmune diseases such as psoriasis and rheumatoid arthritis .

HY-P991261

CJM-112	Interleukin Related	Inflammation/Immunology
CJM-112 is a humanized monoclonal antibody inhibitor targeting interleukin-17A (IL-17A). CJM-112 is promising for research of inflammatory diseases, such as hidradenitis suppurativa associated with abnormal IL-17A-related pathways .

HY-P991146

Lecankitug LZM-012; XKH004	Interleukin Related	Inflammation/Immunology
Lecankitug is a humanized monoclonal antibody targeting human interleukin 17A (IL-17A) and interleukin 17F (IL-17F). Lecankitug specifically binds to *IL-17A* and *IL-17F*, blocking their signal transduction, thus exerting immunosuppressive and anti-inflammatory activities. Lecankitug is promising for research of autoimmune and inflammatory diseases, such as psoriasis and rheumatoid arthritis .

HY-174633

Human IL17A mRNA	mRNA	Inflammation/Immunology
Human IL17A mRNA encodes the human interleukin 17A (IL17A) protein, a member of the IL-17 receptor family. IL17A plays a pivotal role in various infectious diseases, inflammatory and autoimmune disorders, and cancer.

HY-144373

IL-17 modulator 6	Interleukin Related	Inflammation/Immunology
IL-17 modulator 6 (compound 61) is a potent Interleukin 17 (IL-17) modulator (pIC₅₀=9.1). IL-17 modulator 6 has the ability to inhibit IL-17 and can be used for the research of inflammatory and autoimmune diseases .

HY-P991129

Crusekitug QX-002N	Interleukin Related	Inflammation/Immunology
Crusekitug is a humanized monoclonal antibody targeting human interleukin 17A (IL-17A). Crusekitug specifically binds to *IL-17A*, blocking its signal transduction, thus exerting immunosuppressive and anti-inflammatory activities. Crusekitug is promising for research of autoimmune and inflammatory diseases, such as psoriasis and rheumatoid arthritis .

Cat. No.	Product Name	Target	Research Area

HY-P3450

Erepdekinra	Interleukin Related	Inflammation/Immunology
Erepdekinra is an interleukin-17A (IL-17A) receptor antagonist .

Cat. No.	Product Name

HY-K2107

*HOLO Human Interleukin-17A (IL-17A) Detection Kit*
MCE HOLO Human Interleukin-17A (IL-17A) Detection Kit is a homogeneous luminescence-based assay used for the quantitative detection of human IL-17A concentrations in biological samples such as buffer solutions, cell culture supernatants, or serum.

HY-K2108

*HOLO Human Interleukin-17F (IL-17F) Detection Kit*
MCE HOLO Human Interleukin-17F (IL-17F) Detection Kit is a homogeneous luminescence-based assay used for the quantitative detection of human IL-17F concentrations in biological samples such as buffer solutions, cell culture supernatants, or serum.

Cat. No.	Product Name	Target	Research Area	Image

HY-P9925

Brodalumab 4 Publications Verification AMG 827; KHK4827	Interleukin Related	Inflammation/Immunology
Brodalumab (AMG 827) is a human anti-interleukin-17-receptor IgG2 monoclonal antibody that can be used for the research of moderate-to-severe plaque psoriasis and rheumatoid arthritis .

HY-P9927A

Secukinumab (Anti-Human IL-17A) 1 Publications Verification	Interleukin Related	Inflammation/Immunology Cancer
Secukinumab (Anti-Human IL-17A) is a fully human anti-interleukin-17A monoclonal antibody. Anti-Human IL-17A can be used for research in psoriasis pathogenesis .

HY-P991266

SM-17	Interleukin Related	Inflammation/Immunology
SM-17 is a humanized monoclonal antibody inhibitor targeting interleukin 25 (IL-25) and interleukin-17 receptor B (IL17RB). SM-17 is promising for research of immune system diseases .

HY-P99754

Netakimab BCD-085	Interleukin Related	Infection Inflammation/Immunology
Netakimab (BCD-085) is a humanized IgG1κ monoclonal anti-IL-17 antibody that binds to and blocks *IL-17* and *IL-17A* activity, including reduction of downstream IL-6 production. Netakimab can be used for the research of moderate-to-severe plaque psoriasis, ankylosing spondylitis, and COVID-19 with cytokine release syndrome . Recommend Isotype Controls: Human IgG1 kappa, Isotype Control (HY-P99001).

HY-P99335

Vunakizumab Anti-Human IL17A Recombinant Antibody; SHR-1314	Interleukin Related	Inflammation/Immunology
Vunakizumab (Anti-Human IL17A Recombinant Antibody) is a recombinant human IgGκ monoclonal antibody and an *Interleukin-17A* (IL-17A) inhibitor. Vunakizumab binds to IL-17A to inhibit downstream cytokines and block inflammatory signaling. Vunakizumab can be used for the research of chronic plaque psoriasis and ankylosing spondylitis .

HY-P99515

Xeligekimab GR 1501	Interleukin Related	Inflammation/Immunology
Xeligekimab (GR 1501) is an anti-human interleukin 17A (IL-17A) humanized monoclonal antibody. Xeligekimab inhibits the pro-inflammatory cascade. Xeligekimab can be used for the research of inflammatory disease, such as radiographic axial spondyloarthritis .

HY-P991260

CNTO-6785	Interleukin Related	Infection
CNTO-6785 is a humanized monoclonal antibody inhibitor targeting interleukin-17A (IL-17A). CNTO-6785 is promising for research of chronic obstructive pulmonary disease (COPD) .

HY-P991263

SCH-900117	Interleukin Related	Inflammation/Immunology
SCH-900117 is a humanized monoclonal antibody inhibitor targeting interleukin-17A (IL-17A). SCH-900117 is promising for research of autoimmune diseases such as psoriasis and rheumatoid arthritis .

HY-P991261

CJM-112	Interleukin Related	Inflammation/Immunology
CJM-112 is a humanized monoclonal antibody inhibitor targeting interleukin-17A (IL-17A). CJM-112 is promising for research of inflammatory diseases, such as hidradenitis suppurativa associated with abnormal IL-17A-related pathways .

HY-P991146

Lecankitug LZM-012; XKH004	Interleukin Related	Inflammation/Immunology
Lecankitug is a humanized monoclonal antibody targeting human interleukin 17A (IL-17A) and interleukin 17F (IL-17F). Lecankitug specifically binds to *IL-17A* and *IL-17F*, blocking their signal transduction, thus exerting immunosuppressive and anti-inflammatory activities. Lecankitug is promising for research of autoimmune and inflammatory diseases, such as psoriasis and rheumatoid arthritis .

HY-P991129

Crusekitug QX-002N	Interleukin Related	Inflammation/Immunology
Crusekitug is a humanized monoclonal antibody targeting human interleukin 17A (IL-17A). Crusekitug specifically binds to *IL-17A*, blocking its signal transduction, thus exerting immunosuppressive and anti-inflammatory activities. Crusekitug is promising for research of autoimmune and inflammatory diseases, such as psoriasis and rheumatoid arthritis .

Species:	Human (32) Marmoset (1) Rhesus Macaque (6) Mouse (27) Rat (7) Cynomolgus (4) Rabbit (3) Pig (2) Canine (5)
Tag:	His (50) Tag Free (17) Avi (11) Myc (1) Fc (19)
Source:	HEK293 (51) CHO (3) Sf9 insect cells (8) E. coli (25)

Cat. No.	Compare	Product Name	Species	Source	Image

HY-P79326

	IL-17A Protein, Rat (CHO) 3 Publications Verification Il17a; interleukin 17A; Il17; IL-17; CTLA-8; IL-17A; interleukin-17A; interleukin 17 (cytotoxic T-lymphocyte-associated serine esterase 8); cytotoxic T-lymphocyte-associated antigen 8; interleukin 17	Rat	CHO
	The IL-17A protein has important heterodimerization and homodimerization activities and is involved in a variety of processes, including responses to glucocorticoid stimulation and the regulation of cell death and transcription. IL-17A is present in the cytoplasm and extracellular space and has been implicated in diseases such as pancreatitis, inflammatory bowel disease, renal disease, and periodontal disease, and may serve as a biomarker. IL-17A Protein, Rat (CHO) is the recombinant rat-derived IL-17A protein, expressed by CHO , with tag free.

HY-P71856

	IL-17B Protein, Human Cytokine like protein Zcyto7; Cytokine Zcyto7; IL 20 ; IL-17B; IL17B_HUMAN; IL20 ; interleukin 17 beta; interleukin 17B; interleukin-17B; interleukin-20; MGC138900; MGC138901; Neuronal interleukin 17 related factor ; Neuronal interleukin-17-related factor; NIRF; ZCYTO7	Human	E. coli
	IL-17B Proteinas, crucial in cellular signaling, induces the release of pro-inflammatory cytokines, TNF-α, and IL-1β from THP-1 monocytic cells. Its role in regulating immune responses and inflammatory processes underscores its potential significance in mediating crosstalk between immune cells, contributing to overall immune homeostasis. IL-17B Protein, Human is the recombinant human-derived IL-17B protein, expressed by E. coli , with tag free.

HY-P72576

	IL-17RE Protein, Human (HEK293, Fc) IL-17 RE; IL-17 receptor E; IL17RE; interleukin 17 receptor E	Human	HEK293
	Interleukin 17 receptor E (IL-17RE) is a specific functional receptor for IL-17C, and primarily expressed by epithelial cells and lymphocytes, such a Th17 cells. IL-17C/IL-17RE-axis plays a role in many inflammatory and immune diseases. IL-17RE Protein, Human (HEK293, Fc) is produced in HEK293 cells with a C-Terminal Fc-tag.

HY-P72577

	IL-17RE Protein, Mouse (HEK293, His) IL-17 RE; IL-17 receptor E; IL17RE; interleukin 17 receptor E	Mouse	HEK293
	Interleukin 17 receptor E (IL-17RE) is a specific functional receptor for IL-17C, and primarily expressed by epithelial cells and lymphocytes, such a Th17 cells. IL-17C/IL-17RE-axis plays a role in many inflammatory and immune diseases. IL-17RE Protein, Mouse (HEK293, His) is produced in HEK293 cells with six C-Terminal His-tags. It consists of 300 amino acids (A115-H414).

HY-P72794

	IL-17RD Protein, Mouse (CHO) interleukin-17 receptor D; IL-17 receptor D; IL-17RD; mSef; Il17rd; Sef	Mouse	CHO
	Interleukin-17 receptor D (IL-17RD) also known as Sef (similar expression to fibroblast growth factor), is a type I transmembrane protein that can regulate several signaling pathways. Within the cell, IL-17RD expression has been localized mainly to the plasma membrane. IL-17RD is a feedback inhibitor of fibroblast growth factor (FGF) signaling. IL-17RD Protein, Mouse (CHO) is produced in CHO cells, and consists of 2713 amino acids (G29-R299).

HY-P74825

	IL-17RA Protein, Rat (HEK293, His) interleukin-17 receptor A; IL-17RA; CDw217; CD217; IL17R	Rat	HEK293
	IL-17RA (Interleukin 17 receptor A), a receptor for IL-17A and IL-17F, is a type I membrane glycoprotein. It is expressed ubiquitously and exhibits a broad tissue distribution, and plays a role in many inflammatory and autoimmune diseases. IL-17RA is a common co-receptor subunit for other members of the IL-17 family. IL-17RA associates with IL-17RC to form a signaling receptor complex for IL-17A and IL-17F. IL-17RA Protein, Rat (HEK293, His) is produced in HEK293 cells with a C-Terminal His-tag. It consists of 320 amino acids (M1-P320).

HY-P74826

	IL-17RA Protein, Rat (HEK293, hFc) interleukin-17 receptor A; IL-17RA; CDw217; CD217; IL17R	Rat	HEK293
	IL-17RA (Interleukin 17 receptor A), a receptor for IL-17A and IL-17F, is a type I membrane glycoprotein. It is expressed ubiquitously and exhibits a broad tissue distribution, and plays a role in many inflammatory and autoimmune diseases. IL-17RA is a common co-receptor subunit for other members of the IL-17 family. IL-17RA associates with IL-17RC to form a signaling receptor complex for IL-17A and IL-17F. IL-17RA Protein, Rat (HEK293, hFc) is produced in HEK293 cells with a C-Terminal Fc-tag. It consists of 320 amino acids (M1-P320).

HY-P74827

	IL-17RA Protein, Mouse (HEK293, His) interleukin-17 receptor A; IL-17RA; CDw217; CD217; IL17R	Mouse	HEK293
	IL-17RA (Interleukin 17 receptor A), a receptor for IL-17A and IL-17F, is a type I membrane glycoprotein. It is expressed ubiquitously and exhibits a broad tissue distribution, and plays a role in many inflammatory and autoimmune diseases. IL-17RA is a common co-receptor subunit for other members of the IL-17 family. IL-17RA associates with IL-17RC to form a signaling receptor complex for IL-17A and IL-17F. IL-17RA Protein, Mouse (HEK293, His) is produced in HEK293 cells with a C-Terminal His-tag. It consists of 291 amino acids (S32-W322).

HY-P75840

	IL-17RD Protein, Canine (HEK293, His) interleukin-17 receptor D; IL-17RD; IL17Rhom; hSef; IL17RLM; SEF	Canine	HEK293
	Interleukin-17 receptor D (IL-17RD) also known as Sef (similar expression to fibroblast growth factor), is a type I transmembrane protein that can regulate several signaling pathways. Within the cell, IL-17RD expression has been localized mainly to the plasma membrane. IL-17RD is a feedback inhibitor of fibroblast growth factor (FGF) signaling. IL-17RD Protein, Canine (HEK293, His) is produced in HEK293 cells with a His-Terminal Fc-tag.

HY-P76992

	IL-17RA Protein, Rhesus Macaque (HEK293, His) interleukin-17 receptor A; IL-17RA; CDw217; CD217; IL17R	Rhesus Macaque	HEK293
	IL-17RA (Interleukin 17 receptor A), a receptor for IL-17A and IL-17F, is a type I membrane glycoprotein. It is expressed ubiquitously and exhibits a broad tissue distribution, and plays a role in many inflammatory and autoimmune diseases. IL-17RA is a common co-receptor subunit for other members of the IL-17 family. IL-17RA associates with IL-17RC to form a signaling receptor complex for IL-17A and IL-17F. IL-17RA Protein, Rhesus Macaque (HEK293, His) is produced in HEK293 cells with a C-Terminal His-tag. It consists of 320 amino acids (M1-P320).

HY-P72578

	IL-17RD Protein, Human (HEK293, His) interleukin-17 receptor D; IL-17RD; IL17Rhom; hSef; IL17RLM; SEF	Human	HEK293
	Interleukin-17 receptor D (IL-17RD) also known as Sef (similar expression to fibroblast growth factor), is a type I transmembrane protein that can regulate several signaling pathways. Within the cell, IL-17RD expression has been localized mainly to the plasma membrane. IL-17RD is a feedback inhibitor of fibroblast growth factor (FGF) signaling. IL-17RD Protein, Human (HEK293, His) is produced in HEK293 cells with six C-Terminal His-tags.

HY-P72579

	IL-17RD Protein, Mouse (HEK293, His) interleukin-17 receptor D; IL-17RD; IL17Rhom; hSef; IL17RLM; SEF	Mouse	HEK293
	Interleukin-17 receptor D (IL-17RD) also known as Sef (similar expression to fibroblast growth factor), is a type I transmembrane protein that can regulate several signaling pathways. Within the cell, IL-17RD expression has been localized mainly to the plasma membrane. IL-17RD is a feedback inhibitor of fibroblast growth factor (FGF) signaling. IL-17RD Protein, Mouse (HEK293, His) is produced in HEK293 cells with six C-Terminal His-tags.

HY-P75839

	IL-17RD Protein, Canine (HEK293, Fc) interleukin-17 receptor D; IL-17RD; IL17Rhom; hSef; IL17RLM; SEF	Canine	HEK293
	Interleukin-17 receptor D (IL-17RD) also known as Sef (similar expression to fibroblast growth factor), is a type I transmembrane protein that can regulate several signaling pathways. Within the cell, IL-17RD expression has been localized mainly to the plasma membrane. IL-17RD is a feedback inhibitor of fibroblast growth factor (FGF) signaling. IL-17RD Protein, Canine (HEK293, Fc) is produced in HEK293 cells with a C-Terminal Fc-tag.

HY-P76991

	IL-17RA Protein, Rhesus Macaque (HEK293, Fc) interleukin-17 receptor A; IL-17RA; CDw217; CD217; IL17R	Rhesus Macaque	HEK293
	IL-17RA (Interleukin 17 receptor A), a receptor for IL-17A and IL-17F, is a type I membrane glycoprotein. It is expressed ubiquitously and exhibits a broad tissue distribution, and plays a role in many inflammatory and autoimmune diseases. IL-17RA is a common co-receptor subunit for other members of the IL-17 family. IL-17RA associates with IL-17RC to form a signaling receptor complex for IL-17A and IL-17F. IL-17RA Protein, Rhesus Macaque (HEK293, Fc) is produced in HEK293 cells with a C-Terminal Fc-tag. It consists of 320 amino acids (M1-P320).

HY-P72583

	IL-17RA Protein, Mouse (HEK293, Fc) interleukin-17 receptor A; IL-17 receptor A; CDw217; CD217; IL17RA; IL17R	Mouse	HEK293
	IL-17RA (Interleukin 17 receptor A), a receptor for IL-17A and IL-17F, is a type I membrane glycoprotein. It is expressed ubiquitously and exhibits a broad tissue distribution, and plays a role in many inflammatory and autoimmune diseases. IL-17RA is a common co-receptor subunit for other members of the IL-17 family. IL-17RA associates with IL-17RC to form a signaling receptor complex for IL-17A and IL-17F. IL-17RA Protein, Mouse (HEK293, Fc) is produced in HEK293 cells with a C-Terminal Fc-tag. It consists of 291 amino acids (S32-W322).

HY-P72580

	IL-17RC Protein, Human (HEK293, Fc) interleukin-17 receptor C; IL-17 receptor C; IL17RC; IL17Rhom; IL-17RL; ZcytoR14	Human	HEK293
	IL-17RC (Interleukin 17 receptor C), a receptor for IL-17A and IL-17F, is a type I membrane glycoprotein. It is expressed on a variety of nonhematopoietic cell types, and plays a role in inflammatory diseases, including autoimmunity and certain cancers. IL-17RC associates with IL-17RA to form a signaling receptor complex for IL-17A and IL-17F.IL-17RC Protein, Human (HEK293, Fc) is produced in HEK293 cells with a C-Terminal Fc-tag.

HY-P75837

	IL-17RC Protein, Human (sf9, His) interleukin-17 receptor C; IL-17 receptor C; IL17RC; IL17Rhom; IL-17RL; ZcytoR14	Human	Sf9 insect cells
	IL-17RC (Interleukin 17 receptor C), a receptor for IL-17A and IL-17F, is a type I membrane glycoprotein. It is expressed on a variety of nonhematopoietic cell types, and plays a role in inflammatory diseases, including autoimmunity and certain cancers. IL-17RC associates with IL-17RA to form a signaling receptor complex for IL-17A and IL-17F. IL-17RC Protein, Human (sf9, His) is produced in Sf9 insect cells with a C-Terminal His-tag.

HY-P72581

	IL-17RB Protein, Human (HEK293, His) interleukin-17 receptor B; IL-17RB; IL-17Rh1; IL-17B receptor; CRL4; EVI27	Human	HEK293
	IL-17RB (Interleukin 17 receptor B), a protein encoded by the IL17RB gene, is a receptor for the pro-inflammatory cytokines IL17B and IL17E. IL-17RB expression is high in kidney, pancreas, liver, brain, and intestines. IL-17RB may play a role in hematopoietic cell differentiation and growth. IL-17RB is involved in inflammatory diseases and cancers. IL-17RB Protein, Human (HEK293, His) is produced in HEK293 cells with six C-Terminal His-tags.

HY-P72582

	IL-17RB Protein, Mouse (HEK293, His) interleukin-17 receptor B; IL-17RB; IL-17Rh1; IL-17B receptor; CRL4; EVI27	Mouse	HEK293
	IL-17RB (Interleukin 17 receptor B), a protein encoded by the IL17RB gene, is a receptor for the pro-inflammatory cytokines IL17B and IL17E. IL-17RB expression is high in kidney, pancreas, liver, brain, and intestines. IL-17RB may play a role in hematopoietic cell differentiation and growth. IL-17RB is involved in inflammatory diseases and cancers. IL-17RB Protein, Mouse (HEK293, His) is produced in HEK293 cells with six C-Terminal His-tags. It consists of 269 amino acids (R18-G286).

HY-P76419

	IL-17RB Protein, Human (HEK293, Fc) interleukin-17 receptor B; IL-17RB; IL-17Rh1; IL-17B receptor; CRL4; EVI27	Human	HEK293
	IL-17RB (Interleukin 17 receptor B), a protein encoded by the IL17RB gene, is a receptor for the pro-inflammatory cytokines IL17B and IL17E. IL-17RB expression is high in kidney, pancreas, liver, brain, and intestines. IL-17RB may play a role in hematopoietic cell differentiation and growth. IL-17RB is involved in inflammatory diseases and cancers. IL-17RB Protein, Human (HEK293, Fc) is produced in HEK293 cells with a C-Terminal Fc-tag.

HY-P76421

	IL-17RB Protein, Mouse (HEK293, Fc) interleukin-17 receptor B; IL-17RB; IL-17Rh1; IL-17B receptor; CRL4; EVI27	Mouse	HEK293
	IL-17RB (Interleukin 17 receptor B), a protein encoded by the IL17RB gene, is a receptor for the pro-inflammatory cytokines IL17B and IL17E. IL-17RB expression is high in kidney, pancreas, liver, brain, and intestines. IL-17RB may play a role in hematopoietic cell differentiation and growth. IL-17RB is involved in inflammatory diseases and cancers. IL-17RB Protein, Mouse (HEK293, Fc) is produced in HEK293 cells with a C-Terminal Fc-tag. It consists of 286 amino acids (M1-G286).

HY-P77404

	IL-17RB Protein, Rhesus Macaque (HEK293, His) interleukin-17 receptor B; IL-17RB; IL-17Rh1; IL-17B receptor; CRL4; EVI27	Rhesus Macaque	HEK293
	IL-17RB (Interleukin 17 receptor B), a protein encoded by the IL17RB gene, is a receptor for the pro-inflammatory cytokines IL17B and IL17E. IL-17RB expression is high in kidney, pancreas, liver, brain, and intestines. IL-17RB may play a role in hematopoietic cell differentiation and growth. IL-17RB is involved in inflammatory diseases and cancers. IL-17RB Protein, Rhesus Macaque (HEK293, His) is produced in HEK293 cells with a C-Terminal His-tag.

HY-P77405

	IL-17RB Protein, Rhesus Macaque (HEK293, Fc) interleukin-17 receptor B; IL-17RB; IL-17Rh1; IL-17B receptor; CRL4; EVI27	Rhesus Macaque	HEK293
	IL-17RB (Interleukin 17 receptor B), a protein encoded by the IL17RB gene, is a receptor for the pro-inflammatory cytokines IL17B and IL17E. IL-17RB expression is high in kidney, pancreas, liver, brain, and intestines. IL-17RB may play a role in hematopoietic cell differentiation and growth. IL-17RB is involved in inflammatory diseases and cancers. IL-17RB Protein, Rhesus Macaque (HEK293, Fc) is produced in HEK293 cells with a C-Terminal Fc-tag.

HY-P705149

	IL-17RC Protein, Human (Biotinylated, HEK293, Fc-Avi) interleukin-17 receptor C; IL-17 receptor C; IL17RC; IL17Rhom; IL-17RL; ZcytoR14	Human	HEK293

HY-P71963

	IL-17RA Protein, Human (HEK293, hFc) 1 Publications Verification CANDF5; CD217; CD217 antigen; CDw217; CTLA8; HIL 17R; hIL17R; I17RA_HUMAN; IL 17 receptor A; IL 17 receptor; IL 17RA; IL-17 receptor A; IL-17RA; IL17; IL17A receptor; IL17R; IL17RA; IMD51; interleukin 17 receptor A; interleukin-17 receptor A; MGC10262	Human	HEK293
	IL-17RA (Interleukin 17 receptor A), a receptor for IL-17A and IL-17F, is a type I membrane glycoprotein. It is expressed ubiquitously and exhibits a broad tissue distribution, and plays a role in many inflammatory and autoimmune diseases. IL-17RA is a common co-receptor subunit for other members of the IL-17 family. IL-17RA associates with IL-17RC to form a signaling receptor complex for IL-17A and IL-17F. IL-17RA Protein, Human (HEK 293, hFc) is produced in HEK293 cells with a C-Terminal hFc-tag.

HY-P7036

	IL-17A Protein, Human 5+ Cited Publications rHuIL-17; IL-17A; Cytotoxic T-lymphocyte-associated antigen 8; CTLA-8	Human	E. coli
	IL-17A is a homodimeric cytokine and plays a critical role in host defense mechanisms against many bacterial and fungal pathogens as well as allergic and autoimmune responses. IL-17A induces the production of antimicrobial peptides, cytokines, chemokines, and matrix metalloproteinases. IL-17A Protein, Human is a recombinant human IL-17A protein and is expressed in E. coli. It consists of 137 amino acids (I19-A155).

HY-P72383

	IL-17C Protein, Human (Biotinylated, HEK293, His-Avi) CX2; Cytokine CX2; IL17C; IL-17CMGC126884; interleukin 17C; interleukin-17C	Human	HEK293
	IL-17C is an early response cytokine in the defense against bacterial pathogens and upregulates the expression of a variety of antimicrobial peptides. IL-17C stimulates the release of cytokines and is implicated in autoimmune disorders and bacterial infections. IL-17C Protein, Human (Biotinylated, HEK293, His-Avi) is a biotinylated recombinant human IL-17C protein with His tag and Avi tag at the C-terminus and is expressed in HEK293 cells.

HY-P700104AF

	Animal-Free IL-17A Protein, Human (His) Cytotoxic T-lymphocyte-associated antigen 8; CTLA-8	Human	E. coli
	The IL-17A protein is an important effector cytokine that is critical in both innate and adaptive immunity to defend against microorganisms and maintain tissue integrity. It acts through the IL17RA-IL17RC heterodimeric receptor complex, triggering signaling pathways, activating immune-related gene transcription and promoting strong immune inflammation. Animal-Free IL-17A Protein, Human (His) is the recombinant human-derived animal-FreeIL-17A protein, expressed by E. coli , with C-His labeled tag. This product is for cell culture use only.

HY-P74832

	IL-17A/F Heterodimer Protein, Rhesus Macaque (HEK293, His) CTLA-8; IL-17; interleukin-17A; IL17A; interleukin-17F; IL-17F; Cytokine ML-1	Rhesus Macaque	HEK293
	IL-17A-17F Heterodimer Protein is the heterodimer of the cytokines IL-17A and IL-17F. Both IL-17A and IL-17F can induce antimicrobial peptides, cytokines (IL-6 and GM-CSF), chemokines (CCL2, CCL7 and CXCL1), and matrix metalloproteinases (MMP-1 and MMP13). IL-17A-17F shows intermediate biological activity between IL-17A and IL-17F.IL-17A/F Heterodimer Protein, Rhesus Macaque (HEK293, His) is a recombinant rhesus macaque IL-17A-17F heterodimer protein with His tag at the C-terminus and is expressed in HEK293 cells.

HY-P77707

	IL-17A/F Heterodimer Protein, Mouse (HEK293, His-Avi) IL-17A; interleukin-17A; CTLA-8; IL-17; IL-17F; IL24; ML-1; interleukin-17F	Mouse	HEK293
	IL-17A-17F Heterodimer Protein is the heterodimer of the cytokines IL-17A and IL-17F. Both IL-17A and IL-17F can induce antimicrobial peptides, cytokines (IL-6 and GM-CSF), chemokines (CCL2, CCL7 and CXCL1), and matrix metalloproteinases (MMP-1 and MMP13). IL-17A-17F shows intermediate biological activity between IL-17A and IL-17F. IL-17A/F Heterodimer Protein, Mouse (HEK293, His-Avi) is a recombinant mouse IL-17A-17F heterodimer protein with His tag and Avi tag at the C-terminus and is expressed in HEK293 cells.

HY-P77708

	IL-17A/F Heterodimer Protein, Mouse (Biotinylated, HEK293, His-Avi) IL-17A; interleukin-17A; CTLA-8; IL-17; IL-17F; IL24; ML-1; interleukin-17F	Mouse	HEK293
	IL-17A-17F Heterodimer Protein is the heterodimer of the cytokines IL-17A and IL-17F. Both IL-17A and IL-17F can induce antimicrobial peptides, cytokines (IL-6 and GM-CSF), chemokines (CCL2, CCL7 and CXCL1), and matrix metalloproteinases (MMP-1 and MMP13). IL-17A-17F shows intermediate biological activity between IL-17A and IL-17F. IL-17A/F Heterodimer Protein, Mouse (Biotinylated, HEK293, His-Avi) is a biotinylated recombinant mouse IL-17A-17F heterodimer protein with His tag and Avi tag at the C-terminus and is expressed in HEK293 cells.

HY-P77713

	IL-17A/F Heterodimer Protein, Human (Biotinylated, HEK293, His-Avi) IL-17A; interleukin-17A; CTLA-8; IL-17; IL-17F; IL24; ML-1; interleukin-17F	Human	HEK293
	IL-17A-17F Heterodimer Protein is the heterodimer of the cytokines IL-17A and IL-17F. Both IL-17A and IL-17F can induce antimicrobial peptides, cytokines (IL-6 and GM-CSF), chemokines (CCL2, CCL7 and CXCL1), and matrix metalloproteinases (MMP-1 and MMP13). IL-17A-17F shows intermediate biological activity between IL-17A and IL-17F. IL-17A/F Heterodimer Protein, Human (Biotinylated, HEK293, His-Avi) is a biotinylated recombinant human IL-17A-17F heterodimer protein with His tag and Avi tag at the C-terminus and is expressed in HEK293 cells.

HY-P70587

	IL-17D Protein, Human interleukin-17D; IL-17D; IL17D	Human	E. coli
	IL-17D protein acts as a potent inducer, effectively triggering endothelial cells to express key inflammatory mediators such as IL6, CXCL8/IL8, and CSF2/GM-CSF. The ability of this cytokine to stimulate the production of pro-inflammatory signals emphasizes its importance in orchestrating immune responses, particularly in the context of endothelial cell activation. IL-17D Protein, Human is the recombinant human-derived IL-17D protein, expressed by E. coli , with tag free.

HY-P74831

	IL-17F Protein, Mouse Cytokine ML-1; IL17F; interleukin-17F	Mouse	E. coli
	IL-17F is an inflammatory homodimeric cytokine that induces many proinflammatory cytokines and chemokines. IL-17F also induces antimicrobial peptides. IL-17F plays a protective role in colon cancer development and can be used for the research of autoimmune diseases, infection and cancer. IL-17F Protein, Mouse is a recombinant mouse IL-17F protein and is expressed in E. coli. It consists of 133 amino acids (R21-A153).

HY-P73303

	SF20/MYDGF Protein, Mouse interleukin-25; IL-25; interleukin-17E; IL-17E; SF20	Mouse	E. coli
	SF20/MYDGF protein promotes cardiac myocyte survival and adaptive angiogenesis after myocardial infarction (MI). It stimulates endothelial cell proliferation via MAPK1/3, STAT3, and CCND1 signaling, and inhibits cardiac myocyte apoptosis through PI3K/AKT signaling. Given its ability to enhance cardiac function and angiogenesis, SF20/MYDGF protein could be a valuable therapeutic target for improving outcomes in MI patients. SF20/MYDGF Protein, Mouse is the recombinant mouse-derived SF20/MYDGF, expressed by E. coli, with tag-free.

HY-P73170

	IL-17A Protein, Canine CTLA8; CTLA-8; IL-17; interleukin-17A; IL17A	Canine	E. coli
	IL-17A is a homodimeric cytokine and plays a critical role in host defense mechanisms against many bacterial and fungal pathogens as well as allergic and autoimmune responses. IL-17A induces the production of antimicrobial peptides, cytokines, chemokines, and matrix metalloproteinases. IL-17A Protein, Canine is a recombinant canine IL-17A protein and is expressed in E. coli. It consists of 130 amino acids (G26-A155).

HY-P74829

	IL-17F Protein, Rat (sf9, His) Cytokine ML-1; IL17F; interleukin-17F	Rat	Sf9 insect cells
	IL-17F is an inflammatory homodimeric cytokine that induces many proinflammatory cytokines and chemokines. IL-17F also induces antimicrobial peptides. IL-17F plays a protective role in colon cancer development and can be used for the research of autoimmune diseases, infection and cancer. IL-17F Protein, Rat (sf9, His) is a recombinant rat IL-17F protein with His tag at the C-terminus and is expressed in sf9 insect cells. It consists of 153 amino acids (M1-A153).

HY-P700106AF

	Animal-Free IL-17D Protein, Human (His) interleukin-17D; IL-17D; IL17D	Human	E. coli
	IL-17D protein acts as a potent inducer, effectively triggering endothelial cells to express key inflammatory mediators such as IL6, CXCL8/IL8, and CSF2/GM-CSF. The ability of this cytokine to stimulate the production of pro-inflammatory signals emphasizes its importance in orchestrating immune responses, particularly in the context of endothelial cell activation. Animal-Free IL-17D Protein, Human (His) is the recombinant human-derived animal-FreeIL-17D protein, expressed by E. coli , with N-His labeled tag. This product is for cell culture use only.

HY-P73175A

	IL-17A Protein, Rabbit CTLA8; CTLA-8; IL-17; interleukin-17A; IL17A	Rabbit	E. coli
	IL-17A is a homodimeric cytokine and plays a critical role in host defense mechanisms against many bacterial and fungal pathogens as well as allergic and autoimmune responses. IL-17A induces the production of antimicrobial peptides, cytokines, chemokines, and matrix metalloproteinases. IL-17A Protein, Rabbit is a recombinant rabbit IL-17A protein and is expressed in E. coli. It consists of 130 amino acids (G24-A153).

HY-P73174

	IL-17A Protein, Mouse (solution) Maximum Cited Publications 8 Publications Verification CTLA8; CTLA-8; IL-17; interleukin-17A; IL17A	Mouse	E. coli
	IL-17A is a homodimeric cytokine and plays a critical role in host defense mechanisms against many bacterial and fungal pathogens as well as allergic and autoimmune responses. IL-17A induces the production of antimicrobial peptides, cytokines, chemokines, and matrix metalloproteinases. IL-17A Protein, Mouse (solution) is a recombinant mouse IL-17A protein and is expressed in E. coli. It consists of 137 amino acids (T22-A158).

HY-P73175

	IL-17A Protein, Rabbit (solution) 1 Publications Verification CTLA8; CTLA-8; IL-17; interleukin-17A; IL17A	Rabbit	E. coli
	IL-17A is a homodimeric cytokine and plays a critical role in host defense mechanisms against many bacterial and fungal pathogens as well as allergic and autoimmune responses. IL-17A induces the production of antimicrobial peptides, cytokines, chemokines, and matrix metalloproteinases. IL-17A Protein, Rabbit (solution) is a recombinant rabbit IL-17A protein and is expressed in E. coli. It consists of 130 amino acids (G24-A153).

HY-P73171

	IL-17A Protein, Human (CHO) CTLA8; CTLA-8; IL-17; interleukin-17A; IL17A	Human	CHO
	IL-17A is a homodimeric cytokine and plays a critical role in host defense mechanisms against many bacterial and fungal pathogens as well as allergic and autoimmune responses. IL-17A induces the production of antimicrobial peptides, cytokines, chemokines, and matrix metalloproteinases. IL-17A Protein, Human (CHO) is a recombinant human IL-17A protein and is expressed in CHO cells. It consists of 155 amino acids (M1-A155).

HY-P78556

	IL-17A Protein, Rat (His) CTLA8; CTLA-8; IL-17; interleukin-17A; IL17A	Rat	E. coli
	The IL-17A protein has important heterodimerization and homodimerization activities and is involved in a variety of processes, including responses to glucocorticoid stimulation and the regulation of cell death and transcription. IL-17A is present in the cytoplasm and extracellular space and has been implicated in diseases such as pancreatitis, inflammatory bowel disease, renal disease, and periodontal disease, and may serve as a biomarker. IL-17A Protein, Rat is the recombinant rat-derived IL-17A protein, expressed by E. coli.

HY-P74829A

	IL-17F Protein, Rat (sf9, N-His) Cytokine ML-1; IL17F; interleukin-17F	Rat	E. coli
	Rat IL-17F is predicted to have cytokine binding and dimerization activities and is involved in bacterial defense, IL-17-mediated signaling, and regulation of cytokine production. It acts upstream of the inflammatory response, and its homologue to human IL17F has been implicated in chronic mucocutaneous candidiasis. IL-17F Protein, Rat (sf9, N-His) is the recombinant rat-derived IL-17F, Rat, expressed by E. coli , with N-6*His labeled tag.

HY-P72587

	IL-17C Protein, Human (HEK293, His) CX2; Cytokine CX2; IL17C; interleukin-17C	Human	HEK293
	IL-17C is an early response cytokine in the defense against bacterial pathogens and upregulates the expression of a variety of antimicrobial peptides. IL-17C stimulates the release of cytokines and is implicated in autoimmune disorders and bacterial infections. IL-17C Protein, Human (HEK293, His) is a recombinant human IL-17C protein with His tag at the C-terminus and is expressed in HEK293 cells.

HY-P74833

	IL-17A Protein, Cynomolgus (sf9) CTLA8; CTLA-8; IL-17; interleukin-17A; IL17A	Cynomolgus	Sf9 insect cells
	IL-17A is a homodimeric cytokine and plays a critical role in host defense mechanisms against many bacterial and fungal pathogens as well as allergic and autoimmune responses. IL-17A induces the production of antimicrobial peptides, cytokines, chemokines, and matrix metalloproteinases. IL-17A Protein, Cynomolgus (sf9) is a recombinant cynomolgus IL-17A protein and is expressed in sf9 insect cells. It consists of 155 amino acids (M1-A155).

HY-P73174A

	IL-17A Protein, Mouse (E. coli) CTLA8; CTLA-8; IL-17; interleukin-17A; IL17A	Mouse	E. coli
	IL-17A protein is an important effector cytokine that activates the NF-kappa-B and MAPkinase pathways through the IL17RA-IL17RC receptor complex to protect host tissues from microbial threats. As a key Th17 cytokine, IL-17A mediates neutrophil activation, chemotaxis, and contributes to germinal center formation. IL-17A Protein, Mouse (E. coli) is the recombinant mouse-derived IL-17A protein, expressed by E. coli , with tag free.

HY-P75836

	IL-17C Protein, Human (sf9, Fc) CX2; Cytokine CX2; IL17C; interleukin-17C	Human	Sf9 insect cells
	IL-17C is an early response cytokine in the defense against bacterial pathogens and upregulates the expression of a variety of antimicrobial peptides. IL-17C stimulates the release of cytokines and is implicated in autoimmune disorders and bacterial infections. IL-17C Protein, Human (sf9, Fc) is a recombinant human IL-17C protein with hFc tag at the C-terminus and is expressed in Sf9 insect cells.

HY-P700194AF

	Animal-Free IL-17A Protein, Mouse (His) 3 Publications Verification CTLA8; CTLA-8; IL-17; interleukin-17A; IL17A	Mouse	E. coli
	IL-17A protein is an important effector cytokine that activates the NF-kappa-B and MAPkinase pathways through the IL17RA-IL17RC receptor complex to protect host tissues from microbial threats. As a key Th17 cytokine, IL-17A mediates neutrophil activation, chemotaxis, and contributes to germinal center formation. Animal-Free IL-17A Protein, Mouse (His) is the recombinant mouse-derived animal-FreeIL-17A protein, expressed by E. coli , with C-His labeled tag. This product is for cell culture use only.

HY-P72555

	IL-25/IL-17E Protein, Human (HEK293, His) interleukin-25; IL-25; interleukin-17E; IL-17E	Human	HEK293
	IL-25/IL-17E cytokines are produced by eosinophils, Th2 cells, and epithelial cells and critically regulate the adaptive immune response by modulating cytokine production. It enhances local and systemic type 2 helper T cell responses through its IL17RA and IL17RB receptors and activates the JAK2-STAT5A pathway. IL-25/IL-17E Protein, Human (HEK293, His) is the recombinant human-derived IL-25/IL-17E protein, expressed by HEK293 , with C-6*His labeled tag.

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Free Sample	Yes No
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Host:	Rabbit (3)
Reactivity:	Human (2) Rat (1) Mouse (1)
Application:	IHC-P (1) ICC/IF (1) IP (1) IHC-F (1) WB (2) FC (1) ELISA (2)
Isotype:	IgG (3)
Conjugation:	Non-conjugated (3) Biotin (10)
Clonality:	Polyclonal (1) Monoclonal (2) Recombinant (2)
Modification:	Unmodified (3)

Cat. No.	Compare	Product Name	Application	Reactivity	Image

HY-P81114

	IL17A Antibody 2 Publications Verification interleukin-17A; CTLA-8; CTLA 8; CTLA8; Cytotoxic T lymphocyte associated antigen 8; Cytotoxic T lymphocyte associated serine esterase 8; IL 17A; IL-17A; IL-17; interleukin 17; interleukin-17; interleukin 17A; interleukin17; interleukin17A; IL17_HUMAN; IL17_MOUSE.	WB, ELISA, IHC-P, IHC-F, ICC/IF	Mouse, Rat
	IL17A Antibody is a Rabbit-derived and non-conjugated IgG polyclonal antibody, targeting to IL17A.

HY-P81634

	IL-17RA Antibody (YA1379) IL17RA; IL17R; interleukin-17 receptor A; IL-17 receptor A; IL-17RA; CDw217; CD antigen CD217	FC, ELISA	Human
	IL-17RA Antibody (YA1379) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to IL-17RA.

HY-P82900

	IL-17RA Antibody (YA2645) IL17RA; IL17R; interleukin-17 receptor A; IL-17 receptor A; IL-17RA; CDw217; CD antigen CD217	WB, IP	Human
	IL-17RA Antibody (YA2645) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to IL-17RA.

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Cat. No.	Product Name		Classification

HY-174632

Human IL17RA mRNA		mRNA Interleukin & Receptors
Human IL17RA mRNA encodes the human interleukin 17 receptor subunit alpha (IL17RA) protein, a ubiquitous type I membrane glycoprotein that binds with low affinity to interleukin 17A. Interleukin 17A and its receptor play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis.

HY-174633

Human IL17A mRNA		mRNA Interleukin & Receptors
Human IL17A mRNA encodes the human interleukin 17A (IL17A) protein, a member of the IL-17 receptor family. IL17A plays a pivotal role in various infectious diseases, inflammatory and autoimmune disorders, and cancer.

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