2. Immunology/Inflammation
  3. Interleukin Related
  4. Brodalumab

Brodalumab  (Synonyms: AMG 827; KHK4827)

Cat. No.: HY-P9925 Purity: 97.23%
COA

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Brodalumab (AMG 827) is a human anti-interleukin-17-receptor IgG2 monoclonal antibody that can be used for the research of moderate-to-severe plaque psoriasis and rheumatoid arthritis.

For research use only. We do not sell to patients.

Brodalumab Chemical Structure

Brodalumab Chemical Structure

CAS No. : 1174395-19-7

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1 mg USD 190 In-stock
5 mg USD 480 In-stock
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Based on 1 publication(s) in Google Scholar

Brodalumab Related Antibodies

Top Publications Citing Use of Products

1 Publications Citing Use of MCE Brodalumab

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Description

Brodalumab (AMG 827) is a human anti-interleukin-17-receptor IgG2 monoclonal antibody that can be used for the research of moderate-to-severe plaque psoriasis and rheumatoid arthritis[1][2].

IC50 & Target

IL-17R[1]
In Vitro

Brodalumab (AMG 827) blocks the biological activity of IL-17A, IL-17F and IL17-A/F heterodimer signaling through the IL-17RA/RC complex, as well as IL-25 (IL-17E) signaling through the IL-17RA/RB complex[2].
Brodalumab is capable of inhibiting the inflammatory process in psoriasis[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Brodalumab Related Antibodies
Clinical Trial
CAS No.
Appearance

Liquid

Color

Colorless to light yellow

SMILES

[Brodalumab]
Shipping

Shipping with dry ice.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation

Purity: 97.23%

COA (291 KB)

Handling Instructions (2659 KB)
References
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Brodalumab Related Classifications

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Brodalumab1174395-19-7AMG 827 KHK4827AMG827AMG-827KHK4827KHK 4827KHK-4827Interleukin RelatedILplaque psoriasisIL-17rheumatoid arthritisInhibitorinhibitorinhibit

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