1174395-19-7
Chemical Structure
Brodalumab
Synonym(s): AMG 827; KHK4827
- CAS No.: 1174395-19-7
- Formula:N/A
- Molecular Weight:(144.06 kDa)
SMILES: [Brodalumab]
Biological Activity: Brodalumab (AMG 827) is a human anti-interleukin-17-receptor IgG2 monoclonal antibody that can be used for the research of moderate-to-severe plaque psoriasis and rheumatoid arthritis[1][2].
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Brodalumab | 99.18% | Brodalumab (AMG 827) is a human anti-interleukin-17-receptor IgG2 monoclonal antibody that can be used for the research of moderate-to-severe plaque psoriasis and rheumatoid arthritis. | ||||||||||||||||||||
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- [1]. Papp KA, et al. Brodalumab, an anti-interleukin-17-receptor antibody for psoriasis. N Engl J Med. 2012 Mar 29;366(13):1181-9. [Content Brief]
- [2]. Martin DA, et al. A phase Ib multiple ascending dose study evaluating safety, pharmacokinetics, and early clinical response of brodalumab, a human anti-IL-17R antibody, in methotrexate-resistant rheumatoid arthritis. Arthritis Res Ther. 2013 Oct 25;15(5):R164. [Content Brief]
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