18 Results for "

modified nucleotide synthesis

" in MedChemExpress (MCE) Product Catalog:
Products (18)

18 Results for "modified nucleotide synthesis" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-113138
CAS No.: 2140-69-4
Purity:  99.05%
Synonyms: N3-Methyluridine
3-Methyluridine (m 3U; N3-Methyluridine) is a methylated nucleotide present in ribosomal RNA (rRNA), mainly targeting specific base sites of RNA molecules such as 23S rRNA. 3-Methyluridine can introduce a methyl group at the N3 position of uracil, affecting the secondary structure stability and base pairing ability of RNA, and regulating ribosome function. For example, it affects ribosomal subunit binding and tRNA interaction. 3-Methyluridine is often used as a key raw material for the synthesis of modified nucleotides, and is used to construct RNA oligonucleotides containing methylation modifications to study the effects of RNA methylation on gene expression and drug resistance .
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-W008615
CAS No.: 1147-23-5
Synonyms: 5-Iodo-D-cytidine
5-Iodo-cytidine (5-Iodo-D-cytidine) is a purine nucleoside analog that acts as an intermediate in organic synthesis. 5-Iodo-cytidine serves as a chemically modified nucleotide to replace partial cytidine residues in in vitro transcription, enhancing the translation efficiency and stability of chemically modified mRNA. Purine nucleoside analogs exhibit broad anti-tumor activity and target indolent lymphoid malignancies. 5-Iodo-cytidine can be used in mRNA therapy and tumor-related research .
loading...
    loading...
Cat. No.: HY-W570884
CAS No.: 1873306-74-1
Research Areas:  

Others

5-Me-dC(Ac) amidite is an acetyl (Ac)-modified nucleotide commonly used in the synthesis of modified oligonucleotides.
loading...
    loading...
Cat. No.: HY-138602
CAS No.: 159414-98-9
Purity:  99.11%
5'-O-DMT-N4-Ac-2'-F-dC is a modified nucleotide commonly used in the synthesis of modified oligonucleotides.
loading...
    loading...
Cat. No.: HY-148596
CAS No.: 528-04-1
Synonyms: UDP-N-Acetyl-D-glucosamine; Uridine diphospho-N-acetylglucosamine; UDP-N-acetylglucosamine
UDP-GlcNAc (UDP-N-Acetyl-D-glucosamine) is an important component and precursor of bacterial peptidoglycan. UDP-GlcNAc is a nucleotide sugar used by Glycosyltransferases to synthesize glycoproteins, glycosaminoglycans, glycolipids, and glycoRNA. UDP-GlcNAc also serves as the donor substrate for forming O-GlcNAc, a dynamic intracellular protein modification involved in diverse signaling and disease processes. UDP-GlcNAc is the sugar nucleotide donor for the synthesis of O-GlcNAc modified proteins. UDP-GlcNAc also acts as a full agonist of the P2Y14 receptor and inhibits the formation of cAMP. UDP-GlcNAc can be used in studies related to bacterial infections .
loading...
    loading...
Cat. No.: HY-W881465
CAS No.: 2172373-55-4
5'(E)-VP-2'-OMe-U Phosphoramidite is a phosphoramidite nucleotide precursor compound, mainly used to synthesize stable and functionalized modified oligonucleotides for the research and synthesis of nucleic acid drugs.
loading...
    loading...
Cat. No.: HY-132137
CAS No.: 666847-57-0
5-Propargylamino-3'-azidomethyl-dUTP is a nucleoside molecule extracted from patent WO2004018497A2, compound 5. 5-Propargylamino-3'-azidomethyl-dUTP can be used in DNA synthesis and DNA sequencing . 5-Propargylamino-3'-azidomethyl-dUTP is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
loading...
    loading...
Cat. No.: HY-W881466
CAS No.: 2419895-65-9
Research Areas:  

Others

5'(E)-VP-2'-OMe-Bz-A Phosphoramidite is a phosphoramidate nucleotide precursor compound, which is mainly used to synthesize stable and functionalized modified oligonucleotides and is used in the development and synthesis of nucleic acid drugs .
loading...
    loading...
Cat. No.: HY-W1119950
CAS No.: 1644649-86-4
3'-NH-Tr-2',3'-DMF-ddA-5'-CE-Phosphoramidite is an adenine nucleotide monomer precursor used in solid-phase synthesis of oligonucleotides, particularly modified oligonucleotides, such as those with DNA chain end modifications. 3'-NH-Tr-2',3'-DMF-ddA-5'-CE-Phosphoramidite, with trityl (Tr), cyanoethyl (CE), and dimethylformamidine (DMF) protecting groups, is a ddNTP adenosine nucleoside useful in applications such as solid-phase oligonucleotide synthesis, probe design, and chain-termination sequencing .
loading...
    loading...
Cat. No.: HY-132138
CAS No.: 666847-71-8
5-Propargylamino-3'-azidomethyl-dCTP is a nucleoside molecule extracted from patent WO2004018497A2, compound 17. 5-Propargylamino-3'-azidomethyl-dCTP can be used in DNA synthesis and DNA sequencing . 5-Propargylamino-3'-azidomethyl-dCTP is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
loading...
    loading...
Cat. No.: HY-134351
CAS No.: 85280-65-5
Research Areas:  

Metabolic Disease

AA-dUTP tetrasodium is an amine-modified nucleotide that has been used in the synthesis of fluorescently labeled dUTP.
loading...
    loading...
Cat. No.: HY-131799A
Research Areas:  

Others

3'-Amino-3'-deoxyadenosine-5'-O-diphosphate sodium is an amine-modified nucleotide that can be used in the synthesis of other active compounds. The coumarin-labeled derivatives of 3'-Amino-3'-deoxyadenosine-5'-O-diphosphate sodium exhibit significant fluorescence changes when interacting with myosin and can mimic the function of natural ADP .
loading...
    loading...
Cat. No.: HY-177789
Target:  

Phosphoramidites

Research Areas:  

Others

2',3'-ddT Phosphoramidite is a specially modified nucleotide monomer that is specifically used for solid-phase oligonucleotide synthesis. Once 2',3'-ddT Phosphoramidite is incorporated at the end of a DNA chain, it cannot continue to extend through normal phosphodiester bonds, and thus can also be used as a chain terminator.
loading...
    loading...
Cat. No.: HY-164903
CAS No.: 1608127-25-8
Research Areas:  

Others

UDP-D-GalNAlk is an alkyne-modified UDP sugar and unnatural sugar nucleotide. UDP-D-GalNAlk allows in vitro synthesis via mutant AGX1 enzyme. UDP-D-GalNAlk serves as a substrate for engineered GalNAc-T enzymes, enabling the selective installation of alkyne-modified D-GalNAc derivatives in glycoproteomes. UDP-D-GalNAlk is a biochemical reagent used as a biological material or organic compound for life science research .
loading...
    loading...
Cat. No.: HY-183383
CAS No.: 144303-74-2
Synonyms: 4-Thio-DU CEP
Target:  

Phosphoramidites

Research Areas:  

Others

4-Thio-dU CE phosphoramidite (4-Thio-DU CEP) is a special modified nucleotide unit of thymine/uracil structure, used in solid-phase oligonucleotide synthesis to introduce the protected 4-sulfur carbonyl group into the DNA or RNA chain. 4-Thio-dU CE phosphoramidite is mainly used for photocrosslinking, photophilic labeling, nucleic acid structure research, and site-specific functionalization through sulfur atoms after synthesis.
loading...
    loading...
Cat. No.: HY-164903A
CAS No.: 2370947-52-5
Research Areas:  

Others

UDP-D-GalNAlk disodium is an alkyne-modified UDP sugar and unnatural sugar nucleotide. UDP-D-GalNAlk disodium allows in vitro synthesis via mutant AGX1 enzyme. UDP-D-GalNAlk disodium serves as a substrate for engineered GalNAc-T enzymes, enabling the selective installation of alkyne-modified D-GalNAc derivatives in glycoproteomes. UDP-D-GalNAlk disodium is a biochemical reagent used as a biological material or organic compound for life science research .
loading...
    loading...
Cat. No.: HY-185993
Target:  

Phosphoramidites

Research Areas:  

Others

PT-IX Phosphoramidite is a non-nucleotide phosphoramidate reagent that can be used to introduce specific functional groups or modified structures during the synthesis of oligonucleotides. These modifications can confer special physical, chemical or biological properties to the synthesized DNA or RNA molecules, and are widely applied in molecular diagnostics, gene function research, and the development of therapeutic drugs such as nucleic acid aptamers.
loading...
    loading...
Cat. No.: HY-113138R
CAS No.: 2140-69-4
Synonyms: N3-Methyluridine (Standard)
3-Methyluridine (Standard) is the analytical standard of 3-Methyluridine. This product is intended for research and analytical applications. 3-Methyluridine (m3U; N3-Methyluridine) is a methylated nucleotide present in ribosomal RNA (rRNA), mainly targeting specific base sites of RNA molecules such as 23S rRNA. 3-Methyluridine can introduce a methyl group at the N3 position of uracil, affecting the secondary structure stability and base pairing ability of RNA, and regulating ribosome function. For example, it affects ribosomal subunit binding and tRNA interaction. 3-Methyluridine is often used as a key raw material for the synthesis of modified nucleotides, and is used to construct RNA oligonucleotides containing methylation modifications to study the effects of RNA methylation on gene expression and drug resistance .
loading...
    loading...
  • 1