UDP-D-GalNAlk
UDP-D-GalNAlk is an alkyne-modified UDP sugar and unnatural sugar nucleotide. UDP-D-GalNAlk allows in vitro synthesis via mutant AGX1 enzyme. UDP-D-GalNAlk serves as a substrate for engineered GalNAc-T enzymes, enabling the selective installation of alkyne-modified D-GalNAc derivatives in glycoproteomes. UDP-D-GalNAlk is a biochemical reagent used as a biological material or organic compound for life science research.
For research use only. We do not sell to patients.
- CAS No.: 1608127-25-8
- Formula: C20H29N3O17P2
- Molecular Weight:645.40
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
UDP-D-GalNAlk can be biosynthesized in vitro by engineered AGX1(F383A), which accepts alkyne-modified D-GalNAc derivatives bearing butynyl or pentynyl appendages on the N-acetyl carbon[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1608127-25-8
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Molecular Weight 645.40
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Formula C20H29N3O17P2
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SMILES
O[C@@H]1[C@H](O)[C@@H](COP(OP(O[C@@H]2[C@@H]([C@H]([C@H]([C@H](O2)CO)O)O)NC(CCC#C)=O)(O)=O)(O)=O)O[C@H]1N(C(N3)=O)C=CC3=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)