5'(E)-VP-2'-OMe-Bz-A Phosphoramidite
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5'(E)-VP-2'-OMe-Bz-A Phosphoramidite is a phosphoramidate nucleotide precursor compound, which is mainly used to synthesize stable and functionalized modified oligonucleotides and is used in the development and synthesis of nucleic acid drugs.
For research use only. We do not sell to patients.
- Purity: 98.06%
- CAS No.: 2419895-65-9
- Formula: C40H57N7O12P2
- Molecular Weight:889.87
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Storage:
-20°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
All DNA/RNA Synthesis Isoforms
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Biological Activity
5'(E)-VP-2'-OMe-Bz-A Phosphoramidite is a modified phosphoramidite monomer that can be used for the synthesis of DNA and RNA[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2419895-65-9
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Appearance Solid
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Molecular Weight 889.87
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Formula C40H57N7O12P2
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Color White to off-white
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SMILES
CC(C)N(C(C)C)P(O[C@H]1[C@@H](OC)[C@H](N2C(N=CN=C3NC(C4=CC=CC=C4)=O)=C3N=C2)O[C@@H]1/C=C/P(OCOC(C(C)(C)C)=O)(OCOC(C(C)(C)C)=O)=O)OCCC#N
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
Solvent & Solubility
DMSO : 50 mg/mL (56.19 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (277 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.1238 mL | 5.6188 mL | 11.2376 mL | 28.0940 mL |
| 5 mM | 0.2248 mL | 1.1238 mL | 2.2475 mL | 5.6188 mL | |
| 10 mM | 0.1124 mL | 0.5619 mL | 1.1238 mL | 2.8094 mL | |
| 15 mM | 0.0749 mL | 0.3746 mL | 0.7492 mL | 1.8729 mL | |
| 20 mM | 0.0562 mL | 0.2809 mL | 0.5619 mL | 1.4047 mL | |
| 25 mM | 0.0450 mL | 0.2248 mL | 0.4495 mL | 1.1238 mL | |
| 30 mM | 0.0375 mL | 0.1873 mL | 0.3746 mL | 0.9365 mL | |
| 40 mM | 0.0281 mL | 0.1405 mL | 0.2809 mL | 0.7023 mL | |
| 50 mM | 0.0225 mL | 0.1124 mL | 0.2248 mL | 0.5619 mL |