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nematicidal activity

" in MedChemExpress (MCE) Product Catalog:

17

Inhibitors & Agonists

1

Biochemical Assay Reagents

1

Peptides

9

Natural
Products

1

Isotope-Labeled Compounds

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-116090
    Conoidin A
    3 Publications Verification

    		 Parasite Infection Cardiovascular Disease Neurological Disease
    Conoidin A is a cell permeable inhibitor of T. gondii enzyme peroxiredoxin II (TgPrxII) with nematicidal properties. Conoidin A covalently binds to the peroxidatic Cys47 of TgPrxII, irreversibly inhibiting its hyperperoxidation activity with an IC50 of 23 μM. Conoidin A also inhibits hyperoxidation of mammalian PrxI and PrxII (but not PrxIII) . Conoidin A has antioxidant, neuroprotective effects and can be used for the research of ischaemic heart disease .
    Conoidin A
  • HY-N8574
    1-Heptacosanol

    Heptacosan-1-ol

    		 Biochemical Assay Reagents Infection
    1-Heptacosanol (Heptacosan-1-ol) is a long-chain fatty alcohol with antifungal, antibacterial (against Escherichia coli and Staphylococcus aureus), nematicidal, anticancer and antioxidant activities. 1-Heptacosanol can be isolated from leaf extracts of Ficus septica and Lecaniodiscus cupanioides. 1-Heptacosanol not only effectively resists pathogenic fungal infections, but also shows potential against pepper anthracnose in phytopathology. 1-Heptacosanol can be used in the research of fungal infections, cancer and oxidative stress-related diseases .
    1-Heptacosanol
  • HY-W012941
    2-Thiophenecarboxaldehyde

    Thiophene-2-carboxaldehyde

    		 Antibiotic Bacterial Parasite Infection
    2-Thiophenecarboxaldehyde (Thiophene-2-carboxaldehyde) is an antibiotic that exhibits antibacterial and nematicidal activities .
    2-Thiophenecarboxaldehyde
  • HY-P5957
    Omphalotin A

    		Parasite Infection
    Omphalotin A is a cyclic peptide, and shows nematicidal activity .
    Omphalotin A
  • HY-123897
    Chamaejasmenin C

    		Parasite Infection
    Chamaejasmenin C, a biflavanone, shows nematicidal activity against second-stage juveniles (J2s) of B. xylophilus and B. mucronatus .
    Chamaejasmenin C
  • HY-176970
    Antimicrobial agent-45

    		Fungal Bacterial Infection
    Antimicrobial agent-45 (Compound 16) is a broad-spectrum antibacterial agent. Antimicrobial agent-45 exhibits MICs against Cr. neoformans, S. aureus, MRSA and My. intracellulare of 9.25, 74.04, 74.04 and 74.04 μM respectively. Antimicrobial agent-45 can be used for the study of cryptococcal infections .
    Antimicrobial agent-45
  • HY-N3754
    Dihydropinosylvin monomethyl ether

    		Parasite Infection
    Dihydropinosylvin monomethyl ether is a natrual compound with nematicidal activity. Dihydropinosylvin monomethyl ether can inhibit pine wood nematodes infection .
    Dihydropinosylvin monomethyl ether
  • HY-N16542
    n-Butylorsellinate

    		Parasite Infection
    N-Butylorsellinate is a butyl thicoline acid ester that can be found in fungi belonging to the Stereum genus. N-Butylorsellinate exhibits significant larvicide activity .
    n-Butylorsellinate
  • HY-121325
    Fervenulin
    1 Publications Verification

    		 Parasite Infection
    Fervenulin has nematicidal activity and inhibits egg hatch and J2 mortality of M. incognita with MICs of 30 μg/mL and 120 μg/mL, respectively .
    Fervenulin
  • HY-125596
    Lachnumon

    		Parasite Infection
    Lachnumon is a fungal metabolite with nematicidal and antimicrobial activities .
    Lachnumon
  • HY-N14239
    Jietacin A

    		Parasite Infection
    Jietacin A is a nematicide. Jietacin A exhibits nematicidal activity against pine wood nematodes. Jietacin A can be used in studies related to pine wood nematode infection and pine wilt disease .
    Jietacin A
  • HY-W012941R
    2-Thiophenecarboxaldehyde (Standard)

    Thiophene-2-carboxaldehyde (Standard)

    		 Reference Standards Antibiotic Bacterial Parasite Infection
    2-Thiophenecarboxaldehyde (Standard) is the analytical standard of 2-Thiophenecarboxaldehyde. This product is intended for research and analytical applications. 2-Thiophenecarboxaldehyde (Thiophene-2-carboxaldehyde) is an antibiotic that exhibits antibacterial and nematicidal activities .
    2-Thiophenecarboxaldehyde (Standard)
  • HY-172212
    SDH-IN-23

    		Insecticide Reactive Oxygen Species (ROS) Infection
    SDH-IN-23 (Compound B21) is an SDH inhibitor. SDH-IN-23 exhibits excellent nematicidal activity. SDH-IN-23 can inhibit the feeding, reproduction, and embryonic development of nematodes. Meanwhile, SDH-IN-23 exerts a lethal effect on nematodes by triggering oxidative stress, causing intestinal damage, and inhibiting SDH, among other mechanisms .
    SDH-IN-23
  • HY-173264
    SDH-IN-24

    		Parasite Insecticide Infection
    SDH-IN-24 (Compound 51) is an inhibitor of succinate dehydrogenase (SDH). The LC50 against the second-stage juveniles of Bursaphelenchus xylophilus (B. xylophilus) is 6.9 mg/L, and the IC50 for SDH is 15.0 μM. SDH-IN-24 exerts its nematicidal activity by inhibiting the activity of SDH to interfere with the energy metabolism of nematodes. Meanwhile, it inhibits the motility, feeding, and reproduction of nematodes, induces oxidative stress, reduces the protein content of nematodes, and impairs their antioxidant capacity. SDH-IN-24 can be used in the research related to anti-nematode fields .
    SDH-IN-24
  • HY-138074
    Milbemycin A4 oxime

    5-Ketomilbemycin A4 oxime; 5-Oxomilbemycin A4 5-oxime

    		 Parasite Infection
    Milbemycin A4 oxime (5-Ketomilbemycin A4 oxime; 5-Oxomilbemycin A4 5-oxime) is a derivative of Milbemycin A4 (HY-126906) and a component of Milbemycin oxime (HY-B0778), both of which have insecticidal and nematicidal activities. Milbemycin A4 oxime (0.05 mg/kg) reduces the number of microfilariae in naturally infected dogs with D. immitis and inhibits the growth of clinical isolates of Candida glabrata (MIC80=16-32 μg/mL). Milbemycin A4 oxime (2.5 μg/mL) blocks the efflux of Fluconazole (HY-B0101) from clinical isolates of Candida glabrata. Milbemycin A4 oxime enhances doxorubicin-induced cell growth inhibition and increases the intracellular accumulation of doxorubicin and P-glycoprotein substrate Rhodamine 123 (HY-D0816) in doxorubicin-resistant but not sensitive MCF-7 breast cancer cells in a concentration-dependent manner.
    Milbemycin A4 oxime
  • HY-W721828
    2-Thiophenecarboxaldehyde-d3

    Thiophene-2-carboxaldehyde-d3

    		 Isotope-Labeled Compounds Antibiotic Bacterial Parasite Infection
    2-Thiophenecarboxaldehyde-d3 (Thiophene-2-carboxaldehyde-d3) is the deuterium labeled 2-Thiophenecarboxaldehyde (HY-W012941). 2-Thiophenecarboxaldehyde (Thiophene-2-carboxaldehyde) is an antibiotic that exhibits antibacterial and nematicidal activities .
    2-Thiophenecarboxaldehyde-d3
  • HY-N18080
    Parthenin

    		Parasite DNA Alkylator/Crosslinker Bacterial Infection Inflammation/Immunology Cancer
    Parthenin is a pseudoguaianolide-type sesquiterpene lactone present in Parthenium hysterophorus L. Parthenin induces chromosomal aberrations, mainly chromatid breaks, in human peripheral blood lymphocytes. Parthenin exhibits toxicity against Salmonella typhimurium and Escherichia coli strains, with reduced toxicity in the presence of a metabolic activation system (S9). Parthenin acts as an antifeedant against the 6th instar larvae of the tobacco cutworm (Spodoptera litura). Parthenin shows insecticidal activity against adult cowpea weevils (Callosobruchus maculatus). Parthenin inhibits seed germination and seedling growth of sicklepod (Cassia tora). Parthenin possesses nematicidal activity against the 2nd instar larvae of the southern root-knot nematode (Meloidogyne incognita). Parthenin serves as a research agent for studies related to cancer, malaria, amoebiasis, inflammatory diseases, and bacterial infections .
    Parthenin

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