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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
20 Results for "
nematicidal activity
" in MedChemExpress (MCE) Product Catalog:
Products (20)
20 Results for "nematicidal activity" in MCE Product Catalog:
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3 Cited Publications
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Conoidin A is a cell permeable inhibitor of T. gondii enzyme peroxiredoxin II (TgPrxII) with nematicidal properties. Conoidin A covalently binds to the peroxidatic Cys47 of TgPrxII, irreversibly inhibiting its hyperperoxidation activity with an IC50 of 23 μM. Conoidin A also inhibits hyperoxidation of mammalian PrxI and PrxII (but not PrxIII) . Conoidin A has antioxidant, neuroprotective effects and can be used for the research of ischaemic heart disease .
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1-Heptacosanol (Heptacosan-1-ol) is a long-chain fatty alcohol with antifungal, antibacterial (against Escherichia coli and Staphylococcus aureus), nematicidal, anticancer and antioxidant activities. 1-Heptacosanol can be isolated from leaf extracts of Ficus septica and Lecaniodiscus cupanioides. 1-Heptacosanol not only effectively resists pathogenic fungal infections, but also shows potential against pepper anthracnose in phytopathology. 1-Heptacosanol can be used in the research of fungal infections, cancer and oxidative stress-related diseases .
Cat. No.: HY-W012941
CAS No.: 98-03-3
Synonyms: Thiophene-2-carboxaldehyde
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Capparis spinosa L. Ketones, Aldehydes, Acids Metabolic Disease Plants Capparidaceae Endogenous metabolite Disease Research Fields
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Cat. No.: HY-W020785
CAS No.: 98886-44-3
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Fosthiazate is an inhibitor of acetylcholinesterase (Acetylcholinesterase, AChE). Fosthiazate exhibits significant nematicidal activity and systemic insecticidal activity. Fosthiazate is applicable to studies on plant-parasitic nematodes, root-knot diseases, agricultural pests, as well as the ecotoxicology and environmental behavior of organophosphorus compounds .
Cat. No.: HY-P5957
CAS No.: 186511-50-2
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Cat. No.: HY-123897
CAS No.: 89595-70-0
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Cat. No.: HY-176970
CAS No.: 2043299-21-2
Antimicrobial agent-45 (Compound 16) is a broad-spectrum antibacterial agent. Antimicrobial agent-45 exhibits MICs against Cr. neoformans, S. aureus, MRSA and My. intracellulare of 9.25, 74.04, 74.04 and 74.04 μM respectively. Antimicrobial agent-45 can be used for the study of cryptococcal infections .
Cat. No.: HY-N16542
CAS No.: 31489-30-2
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Cat. No.: HY-N3754
CAS No.: 17635-59-5
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Infection Monophenols Pinaceae Pinus pumila (Pall.) Regel Phenols Plants Disease Research Fields
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Cat. No.: HY-125596
CAS No.: 150671-02-6
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Cat. No.: HY-N14239
CAS No.: 109766-61-2
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Cat. No.: HY-W012941R
CAS No.: 98-03-3
Synonyms: Thiophene-2-carboxaldehyde (Standard)
Cat. No.: HY-W020785R
CAS No.: 98886-44-3
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Fosthiazate (Standard) is the analytical standard of Fosthiazate (HY-W020785). This product is intended for research and analytical applications. Fosthiazate is an inhibitor of acetylcholinesterase (Acetylcholinesterase, AChE). Fosthiazate exhibits significant nematicidal activity and systemic insecticidal activity. Fosthiazate is applicable to studies on plant-parasitic nematodes, root-knot diseases, agricultural pests, as well as the ecotoxicology and environmental behavior of organophosphorus compounds .
Cat. No.: HY-172212
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SDH-IN-23 (Compound B21) is an SDH inhibitor. SDH-IN-23 exhibits excellent nematicidal activity. SDH-IN-23 can inhibit the feeding, reproduction, and embryonic development of nematodes. Meanwhile, SDH-IN-23 exerts a lethal effect on nematodes by triggering oxidative stress, causing intestinal damage, and inhibiting SDH, among other mechanisms .
Cat. No.: HY-173264
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SDH-IN-24 (Compound 51) is an inhibitor of succinate dehydrogenase (SDH). The LC50 against the second-stage juveniles of Bursaphelenchus xylophilus (B. xylophilus) is 6.9 mg/L, and the IC50 for SDH is 15.0 μM. SDH-IN-24 exerts its nematicidal activity by inhibiting the activity of SDH to interfere with the energy metabolism of nematodes. Meanwhile, it inhibits the motility, feeding, and reproduction of nematodes, induces oxidative stress, reduces the protein content of nematodes, and impairs their antioxidant capacity. SDH-IN-24 can be used in the research related to anti-nematode fields .
Cat. No.: HY-138074
CAS No.: 93074-04-5
Synonyms: 5-Ketomilbemycin A4 oxime; 5-Oxomilbemycin A4 5-oxime
Milbemycin A4 oxime (5-Ketomilbemycin A4 oxime; 5-Oxomilbemycin A4 5-oxime) is a derivative of Milbemycin A4 (HY-126906) and a component of Milbemycin oxime (HY-B0778), both of which have insecticidal and nematicidal activities. Milbemycin A4 oxime (0.05 mg/kg) reduces the number of microfilariae in naturally infected dogs with D. immitis and inhibits the growth of clinical isolates of Candida glabrata (MIC80=16-32 μg/mL). Milbemycin A4 oxime (2.5 μg/mL) blocks the efflux of Fluconazole (HY-B0101) from clinical isolates of Candida glabrata. Milbemycin A4 oxime enhances doxorubicin-induced cell growth inhibition and increases the intracellular accumulation of doxorubicin and P-glycoprotein substrate Rhodamine 123 (HY-D0816) in doxorubicin-resistant but not sensitive MCF-7 breast cancer cells in a concentration-dependent manner.
Cat. No.: HY-W721828
CAS No.: 116201-41-3
Synonyms: Thiophene-2-carboxaldehyde-d3
Cat. No.: HY-183949
Research Areas:
Insecticidal agent 33 is an AChE inhibitor with nematicidal activity. Insecticidal agent 33 impairs locomotor activity of Caenorhabditis elegans, and induces oxidative damage in Caenorhabditis elegans, including elevated reactive oxygen species (ROS) levels, lipofuscin accumulation, lipid deposition, and disrupted cellular homeostasis. Insecticidal agent 33 can be used for the research of plant-parasitic nematode infection .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
