Fosthiazate
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Fosthiazate is an inhibitor of acetylcholinesterase (Acetylcholinesterase, AChE). Fosthiazate exhibits significant nematicidal activity and systemic insecticidal activity. Fosthiazate is applicable to studies on plant-parasitic nematodes, root-knot diseases, agricultural pests, as well as the ecotoxicology and environmental behavior of organophosphorus compounds.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度 : 99.11%
- CAS 番号: 98886-44-3
- 分子式: C9H18NO3PS2
- 分子量:283.35
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保管条件:Pure form -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
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生物活性
製品説明
体外実験
The degradation half-life of fosthiazate (5 μg/g soil; 20 °C; up to 60 days) is 17.7-46.8 days in non-sterilized soil, while it is 28.4-87.7 days in sterilized soil, indicating that its degradation in soil involves both chemical and microbial processes[2].
Fosthiazate (2-25 μg/mL; 24 h) shows weak adsorption to San Emigdio sandy loam, Arlington sandy loam, and Waukegan silty clay loam, with its linear adsorption coefficient (Kd) ranging from 0.10 to 0.89[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
体内実験
Fosthiazate (2-20 mg/kg soil; 14 or 28 days) reduces AChE activity in Eisenia fetida in a dose-dependent manner and alters the expression of AChE-related genes[3].
Fosthiazate (7.9-31.6 mg/pot; applied to the root zone; 48 h after nematode inoculation) reduces the numbers of root galls, egg masses and nematode eggs in chili peppers infected by M. enterolobii, with the maximum reduction rates of 58.6%, 64.7% and 83.7% respectively observed in Trial 1[4]
Fosthiazate (3 kg a.i./ha; 2 applications; at transplanting and 3 months later) reduces root galls and egg counts by 39.8% and 80.1%, respectively, in the 'Super Hot' pepper cultivar, and by 59.6% and 67.5%, respectively, in the 'Amphawa Hot Pepper' cultivar, in natural root-knot nematode-infested pepper fields in Ubon Ratchathani[4].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:3-week-old Super Hot chili; M. enterolobii KK1 or UB1; greenhouse[4]
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Dosage:7.9, 15.8, 23.7 or 31.6 mg/pot; 5 weeks
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Administration:Applied to root zone 24 h before inoculation with 1000 J2
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Result:Reduced galls by up to 98.7%, egg masses by up to 99.6%, and eggs by up to 100.0% in Trial 1.
化学情報
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CAS 番号 98886-44-3
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性状 Liquid (Density: 1.268±0.10 g/cm3)
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分子量 283.35
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分子式 C9H18NO3PS2
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Color Colorless to light yellow
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SMILES
CC(CC)SP(N1CCSC1=O)(OCC)=O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Pure form -20°C 3 years In solvent -80°C 6 months -20°C 1 month
溶剤 & 溶解度
体外:
DMSO : ≥ 50 mg/mL (176.46 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (290 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.5292 mL | 17.6460 mL | 35.2920 mL | 88.2301 mL |
| 5 mM | 0.7058 mL | 3.5292 mL | 7.0584 mL | 17.6460 mL | |
| 10 mM | 0.3529 mL | 1.7646 mL | 3.5292 mL | 8.8230 mL | |
| 15 mM | 0.2353 mL | 1.1764 mL | 2.3528 mL | 5.8820 mL | |
| 20 mM | 0.1765 mL | 0.8823 mL | 1.7646 mL | 4.4115 mL | |
| 25 mM | 0.1412 mL | 0.7058 mL | 1.4117 mL | 3.5292 mL | |
| 30 mM | 0.1176 mL | 0.5882 mL | 1.1764 mL | 2.9410 mL | |
| 40 mM | 0.0882 mL | 0.4412 mL | 0.8823 mL | 2.2058 mL | |
| 50 mM | 0.0706 mL | 0.3529 mL | 0.7058 mL | 1.7646 mL | |
| 60 mM | 0.0588 mL | 0.2941 mL | 0.5882 mL | 1.4705 mL | |
| 80 mM | 0.0441 mL | 0.2206 mL | 0.4412 mL | 1.1029 mL | |
| 100 mM | 0.0353 mL | 0.1765 mL | 0.3529 mL | 0.8823 mL |
Fosthiazate 関連分類
HY-W020785 関連分類
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