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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
12 Results for "
nerve fiber
" in MedChemExpress (MCE) Product Catalog:
Products (12)
12 Results for "nerve fiber" in MCE Product Catalog:
2
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Butacaine is a reversible nerve conduction blocker. Butacaine acts on the nervous system and nerve fibers, can cause both sensory and motor paralysis. Butacaine inhibits the NavBh currents. Butacaine can form inclusion complexes with α-cyclodextrin (α-CD) and β-cyclodextrin (β-CD). Butacaine is commonly used as a negative control for other local anesthetics .
Cat. No.: HY-P0131A
CAS No.: 2828432-44-4
Synonyms: Laminin (925-933) TFA
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Cat. No.: HY-P0131
CAS No.: 110590-60-8
Synonyms: Laminin (925-933)
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Cat. No.: HY-P991797
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Cat. No.: HY-D1439
CAS No.: 172807-13-5
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RH 795 is a lipophilic potentiometric styryl fluorescent dye (Ex/Em = 530 nm/712 nm). RH 795 stains the cell membranes of sensory cells and nerve fibers in living cells that maintain membrane potential, while it shows weak staining effect on supporting cells. RH 795 supports in vivo and in vitro confocal microscopy imaging of intact living inner ear cells and neuronal components. RH 795 can be used in studies related to hearing loss .
Cat. No.: HY-N13170
CAS No.: 73529-43-8
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Cat. No.: HY-P10522
CAS No.: 106128-97-6
Cat. No.: HY-135487
CAS No.: 154189-40-9
Synonyms: AR-C68397AA free base; AR-C68397XX
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Sibenadet (AR-C68397AA free base) is a dual dopamine D2/β2-adrenoceptor agonist with selective β2-adrenoceptor agonism. Sibenadet inhibits capsaicin-induced plasma protein extravasation in rat trachea. Sibenadet suppresses edema from sensory nerve fiber activation by activating β2-adrenoceptor. Sibenadet is promising for research of chronic obstructive pulmonary disease (COPD) .
Cat. No.: HY-181998
CAS No.: 2902706-25-4
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CN016 is a neuroprotective agent. CN016 inhibits the elevation of pro-inflammatory cytokines G-CSF, GM-CSF and IL-6 induced by Oxaliplatin (HY-17371). CN016 suppresses Paclitaxel (HY-B0015)-induced inflammatory responses and immune cell infiltration into sensory neurons. CN016 protects neurons from Paclitaxel (HY-B0015)-induced neurotoxic damage. CN016 protects mice against Oxaliplatin-induced peripheral neuropathy .
Cat. No.: HY-165518
CAS No.: 128851-55-8
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Neurological Disease Metabolic Disease Inflammation/Immunology
M 16287 is an orally active aldose reductase inhibitor, with an IC50 of 0.08 μM in rats and 0.25 μM in cattle. M 16287 improves lens fiber swelling and vacuolization, prevents galactitol accumulation, delays inositol depletion, inhibits glutathione reduction, restores the NADPH/NADP + ratio to normal, and normalizes lens Na + content and Na +/K + ratio. M 16287 prevents galactose-induced cataract formation in rats. M 16287 improves motor nerve conduction velocity in diabetic rats, partially alleviates histopathological changes in the sciatic nerve, and inhibits sorbitol accumulation. M 16287 can be used in studies related to cataracts and diabetic neuropathy .
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Cat. No.: HY-183857
CAS No.: 410080-55-6
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DD-161515 is a TRPV1/VR1 inhibitor with an IC50 of 0.7 μM in rats. DD-161515 binds to an allosteric site of TRPV1 distinct from that of capsaicin, blocks channel opening, inhibits receptor-mediated calcium ion influx, reduces the excitability of peripheral sensory nerve fibers, and thereby inhibits nociception induced by heat and transmission of chemically induced pain signals. DD-161515 can be used in studies related to inflammatory pain .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
