149-16-6
Chemical Structure
Butacaine
- CAS. Nr.: 149-16-6
- Formula:C18H30N2O2
- Molecular Weight:306.44
IUPAC Name: 3-(dibutylamino)propyl 4-aminobenzoate
InChIKey: HQFWVSGBVLEQGA-UHFFFAOYSA-N
SMILES: CCCCN(CCCOC(C1=CC=C(N)C=C1)=O)CCCC
Biological Activity: Butacaine is a reversible nerve conduction blocker. Butacaine acts on the nervous system and nerve fibers, can cause both sensory and motor paralysis. Butacaine inhibits the NavBh currents. Butacaine can form inclusion complexes with α-cyclodextrin (α-CD) and β-cyclodextrin (β-CD). Butacaine is commonly used as a negative control for other local anesthetics[1][2][3].
| Art. -Nr. | Produktname | Reinheit | Beschreibung | Pricing | |||||||||||||||||||
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Butacaine | 99.76% | Butacaine is a reversible nerve conduction blocker. Butacaine acts on the nervous system and nerve fibers, can cause both sensory and motor paralysis. Butacaine inhibits the NavBh currents. Butacaine can form inclusion complexes with α-cyclodextrin (α-CD) and β-cyclodextrin (β-CD). Butacaine is commonly used as a negative control for other local anesthetics. | ||||||||||||||||||||
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- [1]. Hashemianzadeh S M, et al. Quantum chemical study of the host-guest inclusion complexes of the local anaesthetic drugs, procaine hydrochloride and butacaine hydrochloride, with α-and β-cyclodextrins[J]. Monatshefte für Chemie-Chemical Monthly, 2008, 139(7): 763-771.
- [2]. Miller ZA, et al. Lidocaine induces apoptosis in head and neck squamous cell carcinoma through activation of bitter taste receptor T2R14. Cell Rep. 2023 Dec 26;42(12):113437. [Content Brief]
- [3]. Fan X, et al. Local anesthetics impair the growth and self-renewal of glioblastoma stem cells by inhibiting ZDHHC15-mediated GP130 palmitoylation. Stem Cell Res Ther. 2021 Feb 4;12(1):107. [Content Brief]
Keywords
