2828432-44-4
Chemical Structure
Laminin peptide CDPGYIGSR TFA
Synonym(s): Laminin (925-933) TFA
- CAS No.: 2828432-44-4
- Formula:C42H63F3N12O16S
- Molecular Weight:1081.08
IUPAC Name: L-cysteinyl-L-aspartyl-L-prolylglycyl-L-tyrosyl-L-isoleucylglycyl-L-seryl-L-arginine compound with 2,2,2-trifluoroacetic acid (1:1)
InChIKey: KCSGEDZIDRWIQM-XBWDXPLKSA-N
SMILES: O=C(N(CCC1)[C@@H]1C(NCC(N[C@H](C(N[C@@H]([C@@H](C)CC)C(NCC(N[C@@H](CO)C(N[C@H](C(O)=O)CCCNC(N)=N)=O)=O)=O)=O)CC2=CC=C(O)C=C2)=O)=O)[C@H](CC(O)=O)NC([C@@H](N)CS)=O.OC(C(F)(F)F)=O
Biological Activity: Laminin peptide CDPGYIGSR TFA (Laminin (925-933) TFA) is a peptide fragment derived from the laminin B1 chain that binds to laminin receptors, and acts as a ligand for the laminin receptor. Laminin peptide CDPGYIGSR TFA mediates cell spreading, induces the clustering of receptors with vinculin and α-actinin, regulates the actin cytoskeleton, promotes the formation of stress fibers, and enhances epithelial cell adhesion. Laminin peptide CDPGYIGSR TFA can be used in studies related to tumor metastasis and nerve injury[1][2][3][4][5].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
Laminin peptide CDPGYIGSR TFA | 99.75% | Laminin peptide CDPGYIGSR TFA (Laminin (925-933) TFA) is a peptide fragment derived from the laminin B1 chain that binds to laminin receptors, and acts as a ligand for the laminin receptor. Laminin peptide CDPGYIGSR TFA mediates cell spreading, induces the clustering of receptors with vinculin and α-actinin, regulates the actin cytoskeleton, promotes the formation of stress fibers, and enhances epithelial cell adhesion. Laminin peptide CDPGYIGSR TFA can be used in studies related to tumor metastasis and nerve injury. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
- [1]. Massia SP, et al. Covalently immobilized laminin peptide Tyr-Ile-Gly-Ser-Arg (YIGSR) supports cell spreading and co-localization of the 67-kilodalton laminin receptor with alpha-actinin and vinculin. The Journal of biological chemistry. 1993 Apr 15;268(11):8053-9. [Content Brief]
- [2]. Graf J, et al. A pentapeptide from the laminin B1 chain mediates cell adhesion and binds the 67,000 laminin receptor. Biochemistry. 1987 Nov 03;26(22):6896-900. [Content Brief]
- [3]. Bhagwat N, et al. Biofunctionalization of PEDOT films with laminin-derived peptides. Acta biomaterialia. 2016 Sep 01;41:235-46. [Content Brief]
- [4]. Castellano F, et al. An Overview of l-Amino Acid Oxidase Functions from Bacteria to Mammals: Focus on the Immunoregulatory Phenylalanine Oxidase IL4I1. Molecules (Basel, Switzerland). 2017 Dec 05;22(12):2151. [Content Brief]
- [5]. Itoh S, et al. Effects of a laminin peptide (YIGSR) immobilized on crab-tendon chitosan tubes on nerve regeneration. Journal of biomedical materials research. Part B, Applied biomaterials. 2005 May;73(2):375-82. [Content Brief]
Keywords
