29 Results for "

pleiotropic

" in MedChemExpress (MCE) Product Catalog:
Products (29)

29 Results for "pleiotropic" in MCE Product Catalog:

28
28 Publications Verification
Cat. No.: HY-17571
CAS No.: 50-56-6
Synonyms: α-Hypophamine; Oxytocic hormone
Oxytocin (α-Hypophamine; Oxytocic hormone) is a pleiotropic, hypothalamic peptide known for facilitating parturition, lactation, and prosocial behaviors. Oxytocin can function as a stress-coping molecule with anti-inflammatory, antioxidant, and protective effects especially in the face of adversity or trauma .
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28
28 Publications Verification
Cat. No.: HY-17571A
CAS No.: 6233-83-6
Synonyms: α-Hypophamine acetate; Oxytocic hormone acetate
Oxytocin (α-Hypophamine) acetate is a pleiotropic, hypothalamic peptide known for facilitating parturition, lactation, and prosocial behaviors. Oxytocin acetate can function as a stress-coping molecule with anti-inflammatory, antioxidant, and protective effects especially in the face of adversity or trauma .
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16
16 Cited Publications
Cat. No.: HY-P3216B
Synonyms: 9-Deamidooxytocin TFA
Target:  

Oxytocin Receptor

Research Areas:  

Endocrinology

Oxytocin free acid (9-Deamidooxytocin) TFA is an analog of oxytocin in which the glycinamide residue at position 9 in oxytocin has been replaced by a glycine residue. Oxytocin is a pleiotropic, peptide hormone with broad implications for general health, adaptation, development, reproduction, and social behavior .
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3
3 Cited Publications
Cat. No.: HY-10252
CAS No.: 475488-23-4
Purity:  99.30%
Synonyms: ADW742; GSK 552602A; ADW
Research Areas:  

Endocrinology Cancer

NVP-ADW742 (ADW742) is an orally active, selective IGF-1R tyrosine kinase inhibitor with an IC50 of 0.17 μM. NVP-ADW742 inhibits insulin receptor (InsR) with an IC50 of 2.8 μM. NVP-ADW742 induces pleiotropic antiproliferative/proapoptotic biologic sequelae in tumor cells .
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1
1 Cited Publications
Cat. No.: HY-122506
CAS No.: 119400-86-1
Purity:  99.61%
Salviolone is a natural diterpenoid derivative that can against melanoma cells. Salviolone exhibits a pleiotropic effect against melanoma by hampering cell cycle progression, STAT3 signaling, and malignant phenotype of A375 melanoma cells .
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1
1 Cited Publications
Cat. No.: HY-W011151
CAS No.: 6025-53-2
trans-Zeatinriboside is a zeatin-type cytokinin and plant growth regulator. trans-Zeatinriboside is produced by the terrestrial filamentous cyanobacterium Nostoc sp. HK-01 and Agrobacterium tumefaciens (including Ti plasmid-dependent and Ti plasmid-independent strains). trans-Zeatinriboside is detectable as a cytokinin component in growing crown galls, and accumulates in large amounts in CHRK1-silenced transgenic tobacco accompanied by pleiotropic developmental abnormalities. trans-Zeatinriboside can be used in studies related to crown galls .
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Cat. No.: HY-N2191
CAS No.: 206756-04-9
Ecliptasaponin D is a triterpenoid glucoside isolated from Eclipta alba (L.) Hassk which is the aerial part of Eclipta prostrate. Eclipta prostrate is considered as a nourishing herbal medicine with pleiotropic effects, including anti-inflammatory, hepatoprotective, antioxidant and immunomodulatory [1,2].
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Cat. No.: HY-P3395
CAS No.: 197151-46-5
Synonyms: Human chromogranin A 352–372
Target:  

nAChR

Catestatin human, a catecholamine release-inhibitory peptide, is a pleiotropic peptide involved in cardiovascular protection with its antihypertensive and angiogenic effects. Catestatin human can be used in the study of inflammatory diseases .
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Cat. No.: HY-P1882
CAS No.: 123209-95-0
Target:  

Insecticide

Research Areas:  

Inflammation/Immunology

Type A Allatostatin I is a tridecapeptide. Allatostatins are pleiotropic neuropeptides for inhibition of juvenile hormone synthesis in insects .
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Cat. No.: HY-P3216
CAS No.: 4248-64-0
Synonyms: 9-Deamidooxytocin
Target:  

Oxytocin Receptor

Research Areas:  

Endocrinology

Oxytocin free acid (9-Deamidooxytocin) is an analog of oxytocin in which the glycinamide residue at position 9 in oxytocin has been replaced by a glycine residue. Oxytocin is a pleiotropic, peptide hormone with broad implications for general health, adaptation, development, reproduction, and social behavior .
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Cat. No.: HY-P1786
CAS No.: 123374-34-5
Target:  

Potassium Channel

Research Areas:  

Neurological Disease

Allatostatin II is a decapeptid. Allatostatins are pleiotropic neuropeptides for inhibition of juvenile hormone synthesis in insects .
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Cat. No.: HY-167836
CAS No.: 847-75-6
Target:  

Trk Receptor

Research Areas:  

Neurological Disease

BNN-20 is a synthetic microneurotrophin that mimics brain-derived neurotrophic factor (BDNF) and exhibits area-specific pleiotropic neuroprotective and pro-neurogenic effects. BNN-20 can be utilized in research related to Parkinson's disease .
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Cat. No.: HY-P4720
CAS No.: 145990-81-4
Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology Cancer

Interleukin-6 fragment (human) is a pleiotropic cytokine produced by lymphocytes and non-lymphocytes. The Interleukin-6 fragment (human) coding gene is located on human chromosome 7, with a length of approximately 5 kilobases. Interleukin-6 fragment (human) has potential applications in immune response, acute response, inflammation, tumors, and hematopoiesis .
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Cat. No.: HY-134666A
Research Areas:  

Infection

Dioctatin A hydrochloride is a metabolite of Streptomyces and an inhibitor of human dipeptidyl aminopeptidase II. Dioctatin A hydrochloride can inhibit aflatoxin production by Aspergillus parasiticus with an IC50 of 4.0 μM. Dioctatin A hydrochloride can reduce the mRNA levels of aflatoxin biosynthetic genes and the regulatory gene aflR, inhibit conidiation and decrease the mRNA level of the brlA gene, and also promote kojic acid production. In addition, Dioctatin A hydrochloride can inhibit sterigmatocystin production. Dioctatin A hydrochloride has pleiotropic regulatory effects on the production and differentiation of fungal secondary metabolites .
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Cat. No.: HY-10252A
CAS No.: 475489-15-7
Synonyms: cis-ADW742; cis-GSK 552602A; cis-ADW
Research Areas:  

Inflammation/Immunology

cis-NVP-ADW742 (cis-ADW742) is a cis isomer of NVP-ADW742 (HY-10252). NVP-ADW742 is an orally active, selective IGF-1R tyrosine kinase inhibitor with an IC50 of 0.17 μM. NVP-ADW742 inhibits insulin receptor (InsR) with an IC50 of 2.8 μM. NVP-ADW742 induces pleiotropic antiproliferative/proapoptotic biologic sequelae in tumor cells .
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Cat. No.: HY-E70867
Target:  

TGF-β Receptor

Research Areas:  

Metabolic Disease

TGF-β is a pleiotropic multifunctional cytokine that regulates many cellular processes, such as cell growth, differentiation, apoptosis and cellular homeostasis. Before exerting the biological effects within cells, TGF-β first requires extracellular activation, namely binds to its type II receptor (TGFβR2) and promotes the phosphorylation. TGFβR1 plays an important role in TGF-β signaling transduction and serves as a tumor suppressor. TGFβR2 Recombinant Human Active Protein Kinase is a recombinant TGFβR2 protein that can be used to study TGFβR2-related functions .
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Cat. No.: HY-P1760
CAS No.: 123338-13-6
Target:  

Insecticide

Research Areas:  

Neurological Disease

Allatostatin IV is an octapeptide. Allatostatins are pleiotropic neuropeptides for inhibition of juvenile hormone synthesis in insects .
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Cat. No.: HY-174634
Target:  

mRNA

Research Areas:  

Inflammation/Immunology

Human IL16 mRNA encodes the human interleukin 16 (IL16) protein, a pleiotropic cytokine that functions as a chemoattractant, a modulator of T cell activation, and an inhibitor of HIV replication.
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Cat. No.: HY-174628
Target:  

mRNA

Research Areas:  

Inflammation/Immunology

Human IL1A mRNA encodes the human interleukin 1 alpha (IL1A) protein, a member of the interleukin 1 cytokine family. IL1A is a pleiotropic cytokine involved in various immune responses, inflammatory processes, and hematopoiesis.
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Cat. No.: HY-149004A
CAS No.: 2763730-98-7
Target:  

LPL Receptor

Research Areas:  

Inflammation/Immunology

SLF1081851 (TFA) is a Spns2 inhibitor, inhibits S1P release (IC50=1.93 μM). SLF1081851 (TFA) plays a key role in development and immune system .
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