Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
22 Results for "
preeclampsia
" in MedChemExpress (MCE) Product Catalog:
Products (22)
22 Results for "preeclampsia" in MCE Product Catalog:
85
85 Publications Verification
Cat. No.: HY-18729A
CAS No.: 51298-62-5
Synonyms: NG-Nitroarginine methyl ester hydrochloride
Target:
Research Areas:
L-NAME hydrochloride inhibits NOS with an IC50 of 70 μM. L-NAME is a precursor to NOS inhibitor L-NOARG which has an IC50 value of 1.4 μM. L-NAME hydrochloride requires hydrolysis of the methyl ester by cellular esterases to become a fully functional inhibitor. L-NAME hydrochloride can be used to induce hypertension and preeclampsia models.
1
1 Cited Publications
Synonyms: α-Hydroxybutyric acid
Category:
Human Gut Microbiota Metabolites Ketones, Aldehydes, Acids Disease markers Metabolic Disease Endocrine diseases Endogenous metabolite Disease Research Fields Cardiovascular System Disorder
Target:
1
Target:
1
1 Cited Publications
Cat. No.: HY-P10387
1
1 Cited Publications
Cat. No.: HY-P10387A
Synonyms: CHI 621
Target:
Research Areas:
Infection Neurological Disease Inflammation/Immunology Cancer
Cat. No.: HY-W094475C
CAS No.: 10034-99-8
Synonyms: Epsom salts, for cell culture
Cat. No.: HY-18729
CAS No.: 50903-99-6
Synonyms: NG-Nitroarginine methyl ester
Target:
Research Areas:
L-NAME inhibits NOS with an IC50 of 70 μM. L-NAME is a precursor to NOS inhibitor L-NOARG which has an IC50 value of 1.4 μM. L-NAME requires hydrolysis of the methyl ester by cellular esterases to become a fully functional inhibitor. L-NAME can be used to induce hypertension and preeclampsia models.
Target:
Research Areas:
Dihydralazine sulfate is an antihypertensive hydrazine derivative and also a low-potency genotoxic agent. Dihydralazine sulfate is a direct-acting mutagen with a mixed gene mutation mechanism, which induces DNA fragmentation in the lung, kidney and spleen of mice, and induces sister chromatid exchange in mouse bone marrow cells. Dihydralazine sulfate specifically kills DNA repair-deficient bacteria. Dihydralazine sulfate is a vasodilator and antihypertensive agent that reduces systemic vascular resistance, increases cardiac output and heart rate, thereby lowering blood pressure. Dihydralazine sulfate can be used in research related to hypertension and severe early-onset preeclampsia .
Target:
Research Areas:
mEH-IN-1 (Compound 62) is a potent microsomal epoxide hydrolase (mEH) inhibitor with the IC50 of 2.2 nM. The mEH is a mammalian α/β-fold hydrolase enzyme, expressed in almost all tissues, hydrolyzes a wide range of epoxide containing molecules. The mEH is mainly localized in the endoplasmic reticulum (ER) of eukaryotic cells. mEH-IN-1 can be used for the research of preeclampsia, hypercholanemia and cancer .
Cat. No.: HY-169932
CAS No.: 2956781-84-1
Target:
Research Areas:
APOL1-IN-2 (Compound 467) is the inhibitor for Apolipoprotein 1 (APOL1). APOL1-IN-2 reduces the APOL1 G2/G1 induced cell death in HEK293 with EC50 of 4.74 nM and 14.3 nM. APOL1-IN-2 reduces the APOL1 G2/G1/G0 induced death of trypanosomes with EC50 of 2.24, 6.03 and 3.72 nM, respectively .
Cat. No.: HY-W012790S
CAS No.: 1219798-97-6
Cat. No.: HY-W094477D
CAS No.: 10034-99-8
Synonyms: Epsom salts, for molecular biology
Cat. No.: HY-W094475D
CAS No.: 10034-99-8
Synonyms: Epsom salts, meets analytical specification of Ph. Eur. BP USP FCC
Cat. No.: HY-W101419
CAS No.: 59512-17-3
Target:
Research Areas:
Ibuprofenamide (Compound 136) is a potent microsomal epoxide hydrolase (mEH) inhibitor with an IC50 value of 96 μM. Ibuprofenamide is promising for research of preeclampsia, hypercholanemia and cancer .
Cat. No.: HY-W094475E
CAS No.: 10034-99-8
Synonyms: Epsom salts (Pharmaceutical primary standard, USP)
Cat. No.: HY-152014S
CAS No.: 2692624-00-1
Cat. No.: HY-W012790R
CAS No.: 5094-24-6
- 1
- 2
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
