5094-24-6
5094-24-6
Chemical Structure
Sodium 2-hydroxybutanoate
Synonym(s): 2-Hydroxybutyric acid sodium
- CAS No.: 5094-24-6
- Formula:C4H7NaO3
- Molecular Weight:126.09
IUPAC Name: sodium 2-hydroxybutanoate
InChIKey: MOSCXNXKSOHVSQ-UHFFFAOYSA-M
SMILES: CCC(O)C(O[Na])=O
Biological Activity: Sodium 2-hydroxybutanoate (2-Hydroxybutyric acid sodium) is converted from 2-Aminobutyric acid, with 2-oxobutyric acid as an intermediate metabolite[1]. Sodium 2-hydroxybutanoate is a potential biomarker for type 2 diabetes and preeclampsia[2][4]. Sodium 2-hydroxybutanoate prevents the acetaminophen (AP)-induced liver injury[3].
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Sodium 2-hydroxybutanoate | 98.0% | Sodium 2-hydroxybutanoate (2-Hydroxybutyric acid sodium) is converted from 2-Aminobutyric acid, with 2-oxobutyric acid as an intermediate metabolite. Sodium 2-hydroxybutanoate is a potential biomarker for type 2 diabetes and preeclampsia. Sodium 2-hydroxybutanoate prevents the acetaminophen (AP)-induced liver injury. | ||||||||||||||||||||
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Sodium 2-hydroxybutanoate (Standard) | ≥98% | Sodium 2-hydroxybutanoate is an endogenous metabolite. Sodium 2-hydroxybutanoate (2-Hydroxybutyric acid sodium) is converted from 2-Aminobutyric acid, with 2-oxobutyric acid as an intermediate metabolite. Sodium 2-hydroxybutanoate is a potential biomarker for type 2 diabetes and preeclampsia. Sodium 2-hydroxybutanoate prevents the acetaminophen (AP)-induced liver injury. | ||||||||||||||||||||
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Sodium 2-hydroxybutanoate-d3 | 99.91% | Sodium 2-hydroxybutanoate-d3 is the deuterium labeled Sodium 2-hydroxybutanoate. Sodium 2-hydroxybutanoate (2-Hydroxybutyric acid sodium) is converted from 2-Aminobutyric acid, with 2-oxobutyric acid as an intermediate metabolite. Sodium 2-hydroxybutanoate is a potential biomarker for type 2 diabetes and preeclampsia. Sodium 2-hydroxybutanoate prevents the acetaminophen (AP)-induced liver injury. | ||||||||||||||||||||
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References
- [1]. Landaas S, et al. The formation of 2-hydroxybutyric acid in experimental animals. Clin Chim Acta. 1975 Jan 6;58(1):23-32. [Content Brief]
- [2]. Shantavasinkul PC, et al., Improvement in insulin resistance after gastric bypass surgery is correlated with a decline in plasma 2-hydroxybutyric acid. Surg Obes Relat Dis. 2018 Aug;14(8):1126-1132. [Content Brief]
- [3]. Zheng N, et al., Vancomycin pretreatment attenuates acetaminophen-induced liver injury through 2-hydroxybutyric acid. J Pharm Anal. 2020 Dec;10(6):560-570. [Content Brief]
- [4]. Wang F, et al., Metabolomic analysis-identified 2-hydroxybutyric acid might be a key metabolite of severe preeclampsia. Open Life Sci. 2023 Feb 28;18(1):20220572. [Content Brief]
