2956781-84-1
2956781-84-1
Chemical Structure
APOL1-IN-2
- CAS No.: 2956781-84-1
- Formula:C28H30ClF3N4O5
- Molecular Weight:595.01
InChIKey: WFMGBSQYIQQRGR-SWGYMIDASA-N
SMILES: O=C(N1[C@@H]2C[C@](C)(O)C2)N(CO)C3=C1C(C(F)(F)F)=CC(OCCN(CC4)CCC4(C(N5)=O)C6=C5C=CC(Cl)=C6)=C3
Biological Activity: APOL1-IN-2 (Compound 467) is the inhibitor for Apolipoprotein 1 (APOL1). APOL1-IN-2 reduces the APOL1 G2/G1 induced cell death in HEK293 with EC50 of 4.74 nM and 14.3 nM. APOL1-IN-2 reduces the APOL1 G2/G1/G0 induced death of trypanosomes with EC50 of 2.24, 6.03 and 3.72 nM, respectively[1].
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APOL1-IN-2 | APOL1-IN-2 (Compound 467) is the inhibitor for Apolipoprotein 1 (APOL1). APOL1-IN-2 reduces the APOL1 G2/G1 induced cell death in HEK293 with EC50 of 4.74 nM and 14.3 nM. APOL1-IN-2 reduces the APOL1 G2/G1/G0 induced death of trypanosomes with EC50 of 2.24, 6.03 and 3.72 nM, respectively. | |||||||||||||||||||||
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