APOL1-IN-2
APOL1-IN-2 (Compound 467) is the inhibitor for Apolipoprotein 1 (APOL1). APOL1-IN-2 reduces the APOL1 G2/G1 induced cell death in HEK293 with EC50 of 4.74 nM and 14.3 nM. APOL1-IN-2 reduces the APOL1 G2/G1/G0 induced death of trypanosomes with EC50 of 2.24, 6.03 and 3.72 nM, respectively.
For research use only. We do not sell to patients.
- CAS No.: 2956781-84-1
- Formula: C28H30ClF3N4O5
- Molecular Weight:595.01
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Chemical Information
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CAS No. 2956781-84-1
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Molecular Weight 595.01
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Formula C28H30ClF3N4O5
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SMILES
O=C(N1[C@@H]2C[C@](C)(O)C2)N(CO)C3=C1C(C(F)(F)F)=CC(OCCN(CC4)CCC4(C(N5)=O)C6=C5C=CC(Cl)=C6)=C3
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)