50903-99-6
50903-99-6
Chemical Structure
L-NAME
Synonym(s): NG-Nitroarginine methyl ester
- CAS No.: 50903-99-6
- Formula:C7H15N5O4
- Molecular Weight:233.23
IUPAC Name: methyl Nw-nitro-L-argininate
InChIKey: KCWZGJVSDFYRIX-YFKPBYRVSA-N
SMILES: N[C@@H](CCCNC(N[N+]([O-])=O)=N)C(OC)=O
Biological Activity: L-NAME inhibits NOS with an IC50 of 70 μM. L-NAME is a precursor to NOS inhibitor L-NOARG which has an IC50 value of 1.4 μM. L-NAME requires hydrolysis of the methyl ester by cellular esterases to become a fully functional inhibitor. L-NAME can be used to induce hypertension and preeclampsia models.
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L-NAME | L-NAME inhibits NOS with an IC50 of 70 μM. L-NAME is a precursor to NOS inhibitor L-NOARG which has an IC50 value of 1.4 μM. L-NAME requires hydrolysis of the methyl ester by cellular esterases to become a fully functional inhibitor. L-NAME can be used to induce hypertension and preeclampsia models. | |||||||||||||||||||||
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Keywords
