14 Results for "

radioisotopes

" in MedChemExpress (MCE) Product Catalog:
Products (14)

14 Results for "radioisotopes" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-108309
CAS No.: 1984-15-2
Purity:  ≥98.0%
Synonyms: Methylenediphosphonic acid
Research Areas:  

Others

Medronic acid (Methylenediphosphonic acid) is a methylene-substituted bisphosphonate. Medronic acid has an affinity for the surface of hydroxyapatite crystals in the bone matrix and adheres to them. Medronic acid can be used in complex with radioisotopes in bone imaging. Due to its strong metal chelating ability, medronic acid is also used as a water treatment chemical. In addition, medronic acid is used as a solvent additive to improve peak shape and signal of metal-sensitive metabolites in LC/MS analysis .
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Cat. No.: HY-P99239
CAS No.: 2260767-49-3
Synonyms: HUJ-591; TLX591

Research Areas:  

Cancer

Rosopatamab (HuJ591) is a humanized antiPSMA IgG1 monoclonal antibody that can be used in cancer research, especially prostate cancer. Rosopatamab can be linked to the low-energy beta-emitting radioisotope lutetium-177 ( 177Lu) through the bifunctional chelator DOTA-NHS ester to obtain a radioimmunoconjugate that targets malignant prostate cells with high efficiency .
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Cat. No.: HY-P99834
CAS No.: 2611099-93-3
Synonyms: IAB22M2C; ImaginAb

Research Areas:  

Cancer

Crefmirlimab (IAB22M2C; ImaginAb) is a humanized CD8-specific single-domain antibody. Conjugation of Crefmirlimab with radioisotopes (e.g., 89Zr) enables tumor immune infiltration assessment, autoimmune disease detection, and immunotherapy response monitoring. Crefmirlimab is applicable for cancer research .
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Cat. No.: HY-W004649
CAS No.: 175854-39-4
Tris-BOC-cyclen is a bifunctional chelator. Bifunctional chelators are used to stably link radiometals to the carrier moiety of radiopharmaceuticals .
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Cat. No.: HY-108309R
CAS No.: 1984-15-2
Synonyms: Methylenediphosphonic acid (Standard)
Research Areas:  

Others

Medronic acid (Standard) is the analytical standard of Medronic acid. This product is intended for research and analytical applications. Medronic acid (Methylenediphosphonic acid) is a methylene-substituted bisphosphonate. Medronic acid has affinity for and adheres to the surface of hydroxyapatite crystals in the bone matrix. Medronic acid can be used in bone imaging, while being complexed with radioisotopes. Due to its strong metal-chelating ability, Medronic acid can also be used as a water treatment chemical .
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Cat. No.: HY-110141
CAS No.: 924298-51-1
Purity:  98.02%
Target:  

mGluR

Research Areas:  

Others

ABP688 is a high affinity human mGluR5 antagonist with anKi of 1.7 nM. Radioisotope-labeled ABP688 can be used as a PET tracer for clinical imaging of the mGlu5 receptor .
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Cat. No.: HY-131673
CAS No.: 2153478-57-8
Research Areas:  

Others

p-SCN-Bn-TCMC tetrahydrochloride is a bifunctional chelator that exhibits high reactivity due to its powerful TCMC component, making it effective for binding radio-isotopic heavy metal ions, which are essential in radio-diagnostic imaging applications.
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Cat. No.: HY-D2060
CAS No.: 1188422-44-7
ATTO 740 is a near-infrared dye (Ex/Em: 740/764 nm). ATTO 740 can be conjugated with the Cetuximab antibody (HY-P9905) .
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Cat. No.: HY-W109978
CAS No.: 16385-59-4
Tetrabutylammonium perrhenate is a quaternary ammonium salt belonging to the class of alkylammonium salts. This compound is used as a catalyst in organic synthesis, especially in the production of alkenes and alcohols. Furthermore, due to its ability to bind radioisotopes, it is useful as a radiopharmaceutical in nuclear medicine. Its unique chemical properties make it an essential ingredient in a variety of industrial processes, including petrochemical refining and pharmaceuticals.
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Cat. No.: HY-118124
CAS No.: 24381-12-2
Target:  

Endogenous Metabolite

Research Areas:  

Others

2-Iodoestradiol is a potent human sex hormone binding globulin (SHBG) ligand with a remarkably high affinity for SHBG. 2-Iodoestradiol exhibits competition for the same binding site as dihydrotestosterone in binding to human SHBG. The binding affinity constant of 2-Iodoestradiol at physiological pH and 37 degrees Celsius is 2.4 x 10(9) M-1, exceeding that for SHBG. 2-Iodoestradiol has been shown to bind to serum albumin, but with lower affinity. The radioisotope 125I-derivative of 2-Iodoestradiol has been used to study the binding properties of human SHBG, demonstrating its potential application in biological research .
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Cat. No.: HY-157998
CAS No.: 2760515-88-4
Target:  

mGluR Src

Research Areas:  

Others

mG2N001 is a negative allosteric modulator (NAM) (IC50: 93 nM) of the metabotropic glutamate receptor mGluR2 and binds to mGluR2 as an antagonist (Ki: 63 nM). mG2N001 is microparticle- and plasma-stable, and its radioisotope [11C]mG2N001 can be used in PET imaging. [11C]mG2N001 has good brain heterogeneity and brain penetration, and can selectively accumulate in mGluR2-rich regions, producing high-contrast brain images .
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Cat. No.: HY-P12131
Oxoreotide atexetan citrate is a conjugate of a SSTR-targeting peptide and atexetan. Oxoreotide atexetan citrate is used in combination with radioisotopes such as lead-212 ( 212Pb) to study somatostatin receptor-expressing neuroendocrine tumors (NETs) .
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Cat. No.: HY-156038B
Target:  

Drug Derivative

Research Areas:  

Cancer

(S)-p-SCN-Bn-DOTA TFA is a bifunctional chelator (BFC), a macrocyclic DOTA (HY-W053583) derivative for tumor pretargeting. (S)-p-SCN-Bn-DOTA TFA can be used for the conjugation of peptides and radionuclides, such as as a linker for In-111 labeled radioimmunoconjugates (RICs) for single photon emission tomography (SPECT) and in vitro biodistribution studies .
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Cat. No.: HY-P3335
CAS No.: 250612-06-7
Synonyms: DOTA-RGDfK dimer
SU015 (DOTA-RGDfK dimer) is a Integrin αvβ5 and αvβ3 antagonist. SU015 exhibits comparable affinity for αvβ5 and αvβ3, with relatively higher potency and specificity compared to other integrins. SU015 inhibits αvβ3-mediated cell adhesion to fibrinogen, αvβ3-mediated adhesion of activated platelets to osteopontin, and αvβ5-mediated cell adhesion to vitronectin. SU015 shows potent inhibitory effects on FGF2-induced angiogenesis in the CAM model. SU015 carries a linker arm available for radioisotope conjugation, and acts as a target-specific radioreagent when labeled with 90Y (i.e., RP697) or 177Lu (i.e., RP688). SU015 can be used in studies related to tumor metastasis and tumors .
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