1984-15-2
Chemical Structure
Medronic acid
Synonym(s): Methylenediphosphonic acid
- CAS No.: 1984-15-2
- Formula:CH6O6P2
- Molecular Weight:176.00
IUPAC Name: methylenebis(phosphonic acid)
InChIKey: MBKDYNNUVRNNRF-UHFFFAOYSA-N
SMILES: O=P(O)(O)CP(O)(O)=O
Biological Activity: Medronic acid (Methylenediphosphonic acid) is a methylene-substituted bisphosphonate. Medronic acid has an affinity for the surface of hydroxyapatite crystals in the bone matrix and adheres to them. Medronic acid can be used in complex with radioisotopes in bone imaging. Due to its strong metal chelating ability, medronic acid is also used as a water treatment chemical. In addition, medronic acid is used as a solvent additive to improve peak shape and signal of metal-sensitive metabolites in LC/MS analysis[1][2].
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Medronic acid | 98.0% | Medronic acid (Methylenediphosphonic acid) is a methylene-substituted bisphosphonate. Medronic acid has an affinity for the surface of hydroxyapatite crystals in the bone matrix and adheres to them. Medronic acid can be used in complex with radioisotopes in bone imaging. Due to its strong metal chelating ability, medronic acid is also used as a water treatment chemical. In addition, medronic acid is used as a solvent additive to improve peak shape and signal of metal-sensitive metabolites in LC/MS analysis. | ||||||||||||||||||||
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Medronic acid (Standard) | 99.87% | Medronic acid (Standard) is the analytical standard of Medronic acid. This product is intended for research and analytical applications. Medronic acid (Methylenediphosphonic acid) is a methylene-substituted bisphosphonate. Medronic acid has affinity for and adheres to the surface of hydroxyapatite crystals in the bone matrix. Medronic acid can be used in bone imaging, while being complexed with radioisotopes. Due to its strong metal-chelating ability, Medronic acid can also be used as a water treatment chemical. | ||||||||||||||||||||
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- [1]. Ohta Y, et al. Salt Tolerance Enhancement of Liquid Chromatography-Matrix-Assisted Laser Desorption/Ionization-Mass Spectrometry Using Matrix Additive MethylenediphosphonicAcid. Mass Spectrom (Tokyo). 2014;3(1):A0031. [Content Brief]
- [2]. Lin Y T, et al. Using an In-Sample Addition of Medronic Acid for the Analysis of Purine-and Pyrimidine-Related Derivatives and Its Application in the Study of Lung Adenocarcinoma A549 Cell Lines by LC–MS/MS[J]. Journal of Proteome Research, 2023, 22(5): 1434-1445. [Content Brief]
