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Results for "

sapogenin

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Apoptosis (4) COX (1) Drug Derivative (2) Drug Intermediate (1) Endogenous Metabolite (4) mAChR (3) NF-κB (3) NOD-like Receptor (NLR) (2) Reference Standards (7) ROR (2) Sex Pheromone (1) TNF Receptor (1)
By Research Areas:	Cancer (6) Cardiovascular Disease (4) Endocrinology (1) Infection (2) Inflammation/Immunology (7) Metabolic Disease (4) Neurological Disease (7)

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Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-N0073

Sarsasapogenin 4 Publications Verification Parigenin; Sarsagenin	Endogenous Metabolite NF-κB	Metabolic Disease Inflammation/Immunology Cancer
Sarsasapogenin is a sapogenin from the Chinese medical herb Anemarrhena asphodeloides Bunge, with antidiabetic, anti-oxidative, anticancer and anti-inflamatory activities.

HY-N0496

Ruscogenin Maximum Cited Publications 6 Publications Verification	NOD-like Receptor (NLR)	Cardiovascular Disease
Ruscogenin, an important steroid sapogenin derived from Ophiopogon japonicus, attenuates cerebral ischemia-induced blood-brain barrier dysfunction by suppressing TXNIP/NLRP3 inflammasome activation and the MAPK pathway. Ruscogenin exerts significant anti-inflammatory and anti-thrombotic activities. Ruscogenin has orally bioactivity .

HY-N0839

Quillaic acid 3 Publications Verification Quillaja sapogenin	Apoptosis	Neurological Disease Inflammation/Immunology Cancer
Quillaic acid (Quillaja sapogenin)It is an anti-gastric cancer and anti-proliferation agent that can promote apoptosis of cancer cells. (apoptosis). Quillaic acidAlso has analgesic and local anti-inflammatory activity .

HY-N2253

Neoruscogenin 1 Publications Verification	ROR	Infection Neurological Disease
Neoruscogenin, a member of the steroidal sapogenin family, is a high-affinity agonist of the nuclear receptor RORα (NR1F1) (EC₅₀ = 0.11 µM) .

HY-106353

Smilagenin 1 Publications Verification	mAChR Endogenous Metabolite	Neurological Disease
Smilagenin (SMI) is a small-molecule steroidal sapogenin from Anemarrhena asphodeloides and Pelargonium hortorum widely used in traditional Chinese medicine for treating chronic neurodegeneration diseases . Smilagenin (SMI) improves memory of aged rats by increasing the muscarinic receptor subtype 1 (M1)-receptor density . Smilagenin (SMI) attenuates Aβ(25-35)-induced neurodegenerationvia stimulating the gene expression of brain-derived neurotrophic factor, may represents a novel therapeutic strategy for AD .

HY-N1403

Tigogenin	Apoptosis	Cardiovascular Disease Metabolic Disease Inflammation/Immunology Cancer
Tigogenin is a steroidal sapogenins. Tigogenin can inhibit adipocytic differentiation and induce osteoblastic differentiation in mouse bone marrow stromal cells. Tigogenin can inhibit cells proliferation and induce apoptosis. Tigogenin can be used for the researches of cancer, inflammation, immunology, metabolic and cardiovascular disease, such as mammary gland carcinoma, rheumatoid arthritis, osteoporosis and atherosclerosis .

HY-N0073R

Sarsasapogenin (Standard) Parigenin (Standard); Sarsagenin (Standard)	Reference Standards Endogenous Metabolite NF-κB	Metabolic Disease Inflammation/Immunology Cancer
Sarsasapogenin (Standard) is the analytical standard of Sarsasapogenin. This product is intended for research and analytical applications. Sarsasapogenin is a sapogenin from the Chinese medical herb Anemarrhena asphodeloides Bunge, with antidiabetic, anti-oxidative, anticancer and anti-inflamatory activities.

HY-N11465

(25R)-Spirost-4-ene-3,6,12-trione	Others	Others
(25R)-Spirost-4-ene-3,6,12-trione is a natural product, that can be isolated from T. terrestris L .

HY-N0496R

Ruscogenin (Standard)	Reference Standards NOD-like Receptor (NLR)	Cardiovascular Disease
Ruscogenin (Standard) is the analytical standard of Ruscogenin. This product is intended for research and analytical applications. Ruscogenin, an important steroid sapogenin derived from Ophiopogon japonicus, attenuates cerebral ischemia-induced blood-brain barrier dysfunction by suppressing TXNIP/NLRP3 inflammasome activation and the MAPK pathway. Ruscogenin exerts significant anti-inflammatory and anti-thrombotic activities. Ruscogenin has orally bioactivity .

HY-N0839R

Quillaic acid (Standard) Quillaja sapogenin (Standard)	Apoptosis Reference Standards	Neurological Disease Inflammation/Immunology Cancer
Quillaic acid (Standard) is the analytical standard of Quillaic acid. This product is intended for research and analytical applications. Quillaic acid (Quillaja sapogenin)It is an anti-gastric cancer and anti-proliferation agent that can promote apoptosis of cancer cells. (apoptosis). Quillaic acidAlso has analgesic and local anti-inflammatory activity[1][2][3][4].

HY-N7421

Smilagenin acetate	mAChR	Neurological Disease
Smilagenin acetate is a sapogenin derivative extracted from patent US20030004147A1. Smilagenin acetate increases the expression of acetylcholine m2 receptors and can be used for the research of dementia .

HY-N2253R

Neoruscogenin (Standard)	Reference Standards ROR	Infection Neurological Disease
Neoruscogenin (Standard) is the analytical standard of Neoruscogenin. This product is intended for research and analytical applications. Neoruscogenin, a member of the steroidal sapogenin family, is a high-affinity agonist of the nuclear receptor RORα (NR1F1) (EC₅₀ = 0.11 μM) .

HY-N1403R

Tigogenin (Standard)	Reference Standards Apoptosis	Cardiovascular Disease Metabolic Disease Inflammation/Immunology Cancer
Tigogenin (Standard) is a steroidal sapogenins. Tigogenin (Standard) can inhibit adipocytic differentiation and induce osteoblastic differentiation in mouse bone marrow stromal cells. Tigogenin (Standard) can inhibit cells proliferation and induce apoptosis. Tigogenin (Standard) can be used for the researches of cancer, inflammation, immunology, metabolic and cardiovascular disease, such as mammary gland carcinoma, rheumatoid arthritis, osteoporosis and atherosclerosis .

HY-N8162

Soyasapogenol D	Others	Others
Soyasapogenol D is a methyl-trimethylsilyl derivative of the sapogenin .

HY-P1482R

α-Factor Mating Pheromone, yeast (Standard) Mating Factor α (Standard)	Sex Pheromone Reference Standards	Endocrinology
Sarsasapogenin (Standard) is the analytical standard of Sarsasapogenin. This product is intended for research and analytical applications. Sarsasapogenin is a sapogenin from the Chinese medical herb Anemarrhena asphodeloides Bunge, with antidiabetic, anti-oxidative, anticancer and anti-inflamatory activities.

HY-106353R

Smilagenin (Standard)	Reference Standards mAChR Endogenous Metabolite	Neurological Disease
Smilagenin (Standard) is the analytical standard of Smilagenin. This product is intended for research and analytical applications. Smilagenin (SMI) is a small-molecule steroidal sapogenin from Anemarrhena asphodeloides and Pelargonium hortorum widely used in traditional Chinese medicine for treating chronic neurodegeneration diseases . Smilagenin (SMI) improves memory of aged rats by increasing the muscarinic receptor subtype 1 (M1)-receptor density . Smilagenin (SMI) attenuates Aβ(25-35)-induced neurodegenerationvia stimulating the gene expression of brain-derived neurotrophic factor, may represents a novel therapeutic strategy for AD .

HY-146419

Anti-inflammatory agent 20	NF-κB COX TNF Receptor	Inflammation/Immunology
Anti-inflammatory agent 20 (compound 5a) is a potent inhibitor of NO activity. Anti-inflammatory agent 20 shows anti-inflammatory activity. Anti-inflammatory agent 20 suppresses LPS-induced inflammation via inhibiting the activation of NF-κB and MAPK signaling and thereby reducing IL-6, TNF-α, iNOS, and COX-2 upregulation .

HY-N17945

(25S)-Ruscogenin		Others
(25S)-Ruscogenin is a steroidal sapogenin found in the tubers of Liriope spicata .

HY-N18343

Ebelin lactone	Drug Derivative	Others
Ebelin lactone (Compound 1) is a sapogenin. Ebelin lactone is the acid hydrolysis product of Jujuboside A (HY-N0659) and Jujuboside B (HY-N0660) .

HY-106353A

epi-Smilagenin	Drug Derivative	Others
epi-Smilagenin is a 5β-spirostan-3α-ol and steroidal sapogenin. epi-Smilagenin can be found in the rumen content of sheep intoxicated by Brachiaria decumbens .

HY-N17493

Spinosic acid A	Others	Others
Spinosic acid A is a triterpene sapogenin. Spinosic acid A is found in Randia spinosa(Thunb.) Poir. .

HY-N17637

Machaeric acid	Drug Intermediate	Others
Machaeric acid is a triterpenoid and triterpene sapogenin, which serves as the aglycone of Senegaloside A; it can be isolated from the seeds of Caragana microphylla Lam. and Acacia senegal(Mimosaceae). Machaeric acid exhibits remarkable biosafety, and even at concentrations as high as 200 μM, it does not induce cytotoxicity or reduce the viability of H4IIE rat hepatoma cells .

HY-N18174

Glaucogenin E	Others	Others
Glaucogenin E is a C₂₁ steroid sapogenin found in rhizomes of Cynanchum stauntonii (Decne.) Schltr. ex Levl. Glaucogenin E shows no cytotoxic activity against human cancer cells .

Cat. No.	Product Name	Target	Research Area

HY-P1482R

α-Factor Mating Pheromone, yeast (Standard) Mating Factor α (Standard)	Sex Pheromone Reference Standards	Endocrinology
Sarsasapogenin (Standard) is the analytical standard of Sarsasapogenin. This product is intended for research and analytical applications. Sarsasapogenin is a sapogenin from the Chinese medical herb Anemarrhena asphodeloides Bunge, with antidiabetic, anti-oxidative, anticancer and anti-inflamatory activities.

Sarsasapogenin 4 Publications Verification Parigenin; Sarsagenin	Liliaceae Classification of Application Fields Metabolic Disease Anemarrhena asphodeloides Bunge Plants Endogenous metabolite Inflammation/Immunology Disease Research Fields Steroids Source Classification	Endogenous Metabolite NF-κB
Sarsasapogenin is a sapogenin from the Chinese medical herb Anemarrhena asphodeloides Bunge, with antidiabetic, anti-oxidative, anticancer and anti-inflamatory activities.

Ruscogenin Maximum Cited Publications 6 Publications Verification	Ophiopogon japonicus (L. f.) Ker-Gawl. Cardiovascular Disease Liliaceae Classification of Application Fields Plants Disease Research Fields Steroids Source Classification	NOD-like Receptor (NLR)
Ruscogenin, an important steroid sapogenin derived from Ophiopogon japonicus, attenuates cerebral ischemia-induced blood-brain barrier dysfunction by suppressing TXNIP/NLRP3 inflammasome activation and the MAPK pathway. Ruscogenin exerts significant anti-inflammatory and anti-thrombotic activities. Ruscogenin has orally bioactivity .

Quillaic acid 3 Publications Verification Quillaja sapogenin	Triterpenes other families Classification of Application Fields Terpenoids Other Diseases Plants Disease Research Fields Source Classification	Apoptosis
Quillaic acid (Quillaja sapogenin)It is an anti-gastric cancer and anti-proliferation agent that can promote apoptosis of cancer cells. (apoptosis). Quillaic acidAlso has analgesic and local anti-inflammatory activity .

Neoruscogenin 1 Publications Verification	Liliaceae Plants Ruscus aculeata Linn. Steroids Source Classification	ROR
Neoruscogenin, a member of the steroidal sapogenin family, is a high-affinity agonist of the nuclear receptor RORα (NR1F1) (EC₅₀ = 0.11 µM) .

Smilagenin 1 Publications Verification	Structural Classification Liliaceae Pelargonium hortorum Bailey Neurological Disease Classification of Application Fields Anemarrhena asphodeloides Bunge Plants Geraniaceae Disease Research Fields Steroids	mAChR Endogenous Metabolite
Smilagenin (SMI) is a small-molecule steroidal sapogenin from Anemarrhena asphodeloides and Pelargonium hortorum widely used in traditional Chinese medicine for treating chronic neurodegeneration diseases . Smilagenin (SMI) improves memory of aged rats by increasing the muscarinic receptor subtype 1 (M1)-receptor density . Smilagenin (SMI) attenuates Aβ(25-35)-induced neurodegenerationvia stimulating the gene expression of brain-derived neurotrophic factor, may represents a novel therapeutic strategy for AD .

Tigogenin	Classification of Application Fields Metabolic Disease Agavaceae Plants Agave sisalana Perr. ex Engelm. Disease Research Fields Steroids Source Classification	Apoptosis
Tigogenin is a steroidal sapogenins. Tigogenin can inhibit adipocytic differentiation and induce osteoblastic differentiation in mouse bone marrow stromal cells. Tigogenin can inhibit cells proliferation and induce apoptosis. Tigogenin can be used for the researches of cancer, inflammation, immunology, metabolic and cardiovascular disease, such as mammary gland carcinoma, rheumatoid arthritis, osteoporosis and atherosclerosis .

Sarsasapogenin (Standard) Parigenin (Standard); Sarsagenin (Standard)	Structural Classification Liliaceae Anemarrhena asphodeloides Bunge Plants Endogenous metabolite Steroids Source Classification	Reference Standards Endogenous Metabolite NF-κB
Sarsasapogenin (Standard) is the analytical standard of Sarsasapogenin. This product is intended for research and analytical applications. Sarsasapogenin is a sapogenin from the Chinese medical herb Anemarrhena asphodeloides Bunge, with antidiabetic, anti-oxidative, anticancer and anti-inflamatory activities.

(25R)-Spirost-4-ene-3,6,12-trione	Tribulus terrester Linn. Zygophyllaceae Plants Steroids Source Classification	Others
(25R)-Spirost-4-ene-3,6,12-trione is a natural product, that can be isolated from T. terrestris L .

Ruscogenin (Standard)	Ophiopogon japonicus (L. f.) Ker-Gawl. Structural Classification Liliaceae Plants Steroids Source Classification	Reference Standards NOD-like Receptor (NLR)
Ruscogenin (Standard) is the analytical standard of Ruscogenin. This product is intended for research and analytical applications. Ruscogenin, an important steroid sapogenin derived from Ophiopogon japonicus, attenuates cerebral ischemia-induced blood-brain barrier dysfunction by suppressing TXNIP/NLRP3 inflammasome activation and the MAPK pathway. Ruscogenin exerts significant anti-inflammatory and anti-thrombotic activities. Ruscogenin has orally bioactivity .

Quillaic acid (Standard) Quillaja sapogenin (Standard)	Triterpenes Structural Classification other families Terpenoids Plants Source Classification	Apoptosis Reference Standards
Quillaic acid (Standard) is the analytical standard of Quillaic acid. This product is intended for research and analytical applications. Quillaic acid (Quillaja sapogenin)It is an anti-gastric cancer and anti-proliferation agent that can promote apoptosis of cancer cells. (apoptosis). Quillaic acidAlso has analgesic and local anti-inflammatory activity[1][2][3][4].

Neoruscogenin (Standard)	Structural Classification Liliaceae Plants Ruscus aculeata Linn. Steroids Source Classification	Reference Standards ROR
Neoruscogenin (Standard) is the analytical standard of Neoruscogenin. This product is intended for research and analytical applications. Neoruscogenin, a member of the steroidal sapogenin family, is a high-affinity agonist of the nuclear receptor RORα (NR1F1) (EC₅₀ = 0.11 μM) .

Tigogenin (Standard)	Structural Classification Agavaceae Plants Agave sisalana Perr. ex Engelm. Steroids Source Classification	Reference Standards Apoptosis
Tigogenin (Standard) is a steroidal sapogenins. Tigogenin (Standard) can inhibit adipocytic differentiation and induce osteoblastic differentiation in mouse bone marrow stromal cells. Tigogenin (Standard) can inhibit cells proliferation and induce apoptosis. Tigogenin (Standard) can be used for the researches of cancer, inflammation, immunology, metabolic and cardiovascular disease, such as mammary gland carcinoma, rheumatoid arthritis, osteoporosis and atherosclerosis .

Soyasapogenol D	Triterpenes Trifolium pratense L. Classification of Application Fields Leguminosae Terpenoids Other Diseases Plants Disease Research Fields Source Classification	Others
Soyasapogenol D is a methyl-trimethylsilyl derivative of the sapogenin .

α-Factor Mating Pheromone, yeast (Standard) Mating Factor α (Standard)	Natural Products Microorganisms Source Classification	Sex Pheromone Reference Standards
Sarsasapogenin (Standard) is the analytical standard of Sarsasapogenin. This product is intended for research and analytical applications. Sarsasapogenin is a sapogenin from the Chinese medical herb Anemarrhena asphodeloides Bunge, with antidiabetic, anti-oxidative, anticancer and anti-inflamatory activities.

Smilagenin (Standard)	Liliaceae Pelargonium hortorum Bailey Anemarrhena asphodeloides Bunge Plants Geraniaceae Steroids	Reference Standards mAChR Endogenous Metabolite
Smilagenin (Standard) is the analytical standard of Smilagenin. This product is intended for research and analytical applications. Smilagenin (SMI) is a small-molecule steroidal sapogenin from Anemarrhena asphodeloides and Pelargonium hortorum widely used in traditional Chinese medicine for treating chronic neurodegeneration diseases . Smilagenin (SMI) improves memory of aged rats by increasing the muscarinic receptor subtype 1 (M1)-receptor density . Smilagenin (SMI) attenuates Aβ(25-35)-induced neurodegenerationvia stimulating the gene expression of brain-derived neurotrophic factor, may represents a novel therapeutic strategy for AD .

(25S)-Ruscogenin	Triterpenes Structural Classification Terpenoids Brodiaea californica Lindl. ex Lem. Plants Asparagaceae Juss. Source Classification
(25S)-Ruscogenin is a steroidal sapogenin found in the tubers of Liriope spicata .

Ebelin lactone	Structural Classification Plants Actaea simplex (DC.) Wormsk. ex Fisch. & C. A. Mey. Rhamnaceae Steroids Source Classification	Drug Derivative
Ebelin lactone (Compound 1) is a sapogenin. Ebelin lactone is the acid hydrolysis product of Jujuboside A (HY-N0659) and Jujuboside B (HY-N0660) .

epi-Smilagenin	Structural Classification Brachiaria eruciformis (Sm.) Griseb. Poaceae Plants Steroids Source Classification	Drug Derivative
epi-Smilagenin is a 5β-spirostan-3α-ol and steroidal sapogenin. epi-Smilagenin can be found in the rumen content of sheep intoxicated by Brachiaria decumbens .

Spinosic acid A	Triterpenes Structural Classification Terpenoids Rubiaceae Catunaregam spinosa (Thunb.) Tirveng. Plants Source Classification	Others
Spinosic acid A is a triterpene sapogenin. Spinosic acid A is found in Randia spinosa(Thunb.) Poir. .

Machaeric acid	Structural Classification Caragana microphylla Lam. Terpenoids Plants Pentacyclic Triterpenoids Fabaceae Source Classification	Drug Intermediate
Machaeric acid is a triterpenoid and triterpene sapogenin, which serves as the aglycone of Senegaloside A; it can be isolated from the seeds of Caragana microphylla Lam. and Acacia senegal(Mimosaceae). Machaeric acid exhibits remarkable biosafety, and even at concentrations as high as 200 μM, it does not induce cytotoxicity or reduce the viability of H4IIE rat hepatoma cells .

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sapogenin

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