25 Results for "

sapogenin

" in MedChemExpress (MCE) Product Catalog:
Products (25)

25 Results for "sapogenin" in MCE Product Catalog:

7
7 Publications Verification
Cat. No.: HY-N0496
CAS No.: 472-11-7
Ruscogenin, an important steroid sapogenin derived from Ophiopogon japonicus, attenuates cerebral ischemia-induced blood-brain barrier dysfunction by suppressing TXNIP/NLRP3 inflammasome activation and the MAPK pathway. Ruscogenin exerts significant anti-inflammatory and anti-thrombotic activities. Ruscogenin has orally bioactivity .
loading...
    loading...
4
4 Cited Publications
Cat. No.: HY-N0073
CAS No.: 126-19-2
Synonyms: Parigenin; Sarsagenin
Sarsasapogenin is a sapogenin from the Chinese medical herb Anemarrhena asphodeloides Bunge, with antidiabetic, anti-oxidative, anticancer and anti-inflamatory activities.
loading...
    loading...
3
3 Cited Publications
Cat. No.: HY-N0839
CAS No.: 631-01-6
Synonyms: Quillaja sapogenin
Quillaic acid (Quillaja sapogenin)It is an anti-gastric cancer and anti-proliferation agent that can promote apoptosis of cancer cells. (apoptosis). Quillaic acidAlso has analgesic and local anti-inflammatory activity .
loading...
    loading...
3
3 Cited Publications
Cat. No.: HY-N0597
CAS No.: 32791-84-7
Panaxatriol is an orally active dammarane-type tetracyclic triterpene sapogenin. Panaxatriol enhances the phosphorylation levels of Akt, insulin receptor and p70S6K in skeletal muscle. Panaxatriol reduces the mRNA expression level of Atrogin1 in skeletal muscle. Panaxatriol induces apoptosis, pre-G1 cell cycle arrest and increased intracellular ROS levels in prostate cancer cells, decreases mitochondrial membrane potential, inhibits cell migration and reduces colony formation. Panaxatriol can be used in research related to insulin resistance, myocardial ischemia/reperfusion injury and prostate cancer [1][2][3].
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-N2253
CAS No.: 17676-33-4
Target:  

ROR

Neoruscogenin, a member of the steroidal sapogenin family, is a high-affinity agonist of the nuclear receptor RORα (NR1F1) (EC50 = 0.11 µM) .
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-106353
CAS No.: 126-18-1
Purity:  ≥98.0%
Smilagenin (SMI) is a small-molecule steroidal sapogenin from Anemarrhena asphodeloides and Pelargonium hortorum widely used in traditional Chinese medicine for treating chronic neurodegeneration diseases . Smilagenin (SMI) improves memory of aged rats by increasing the muscarinic receptor subtype 1 (M1)-receptor density . Smilagenin (SMI) attenuates Aβ(25-35)-induced neurodegenerationvia stimulating the gene expression of brain-derived neurotrophic factor, may represents a novel therapeutic strategy for AD .
loading...
    loading...
Cat. No.: HY-N1403
CAS No.: 77-60-1
Tigogenin is a steroidal sapogenins. Tigogenin can inhibit adipocytic differentiation and induce osteoblastic differentiation in mouse bone marrow stromal cells. Tigogenin can inhibit cells proliferation and induce apoptosis. Tigogenin can be used for the researches of cancer, inflammation, immunology, metabolic and cardiovascular disease, such as mammary gland carcinoma, rheumatoid arthritis, osteoporosis and atherosclerosis .
loading...
    loading...
Cat. No.: HY-N0073R
CAS No.: 126-19-2
Synonyms: Parigenin (Standard); Sarsagenin (Standard)
Sarsasapogenin (Standard) is the analytical standard of Sarsasapogenin. This product is intended for research and analytical applications. Sarsasapogenin is a sapogenin from the Chinese medical herb Anemarrhena asphodeloides Bunge, with antidiabetic, anti-oxidative, anticancer and anti-inflamatory activities.
loading...
    loading...
Cat. No.: HY-N11465
CAS No.: 214681-62-6
(25R)-Spirost-4-ene-3,6,12-trione is a natural product, that can be isolated from T. terrestris L .
loading...
    loading...
Cat. No.: HY-N0496R
CAS No.: 472-11-7
Ruscogenin (Standard) is the analytical standard of Ruscogenin. This product is intended for research and analytical applications. Ruscogenin, an important steroid sapogenin derived from Ophiopogon japonicus, attenuates cerebral ischemia-induced blood-brain barrier dysfunction by suppressing TXNIP/NLRP3 inflammasome activation and the MAPK pathway. Ruscogenin exerts significant anti-inflammatory and anti-thrombotic activities. Ruscogenin has orally bioactivity .
loading...
    loading...
Cat. No.: HY-N0839R
CAS No.: 631-01-6
Synonyms: Quillaja sapogenin (Standard)
Quillaic acid (Standard) is the analytical standard of Quillaic acid. This product is intended for research and analytical applications. Quillaic acid (Quillaja sapogenin)It is an anti-gastric cancer and anti-proliferation agent that can promote apoptosis of cancer cells. (apoptosis). Quillaic acidAlso has analgesic and local anti-inflammatory activity[1][2][3][4].
loading...
    loading...
Cat. No.: HY-N7421
CAS No.: 4947-75-5
Target:  

mAChR

Research Areas:  

Neurological Disease

Smilagenin acetate is a sapogenin derivative extracted from patent US20030004147A1. Smilagenin acetate increases the expression of acetylcholine m2 receptors and can be used for the research of dementia .
loading...
    loading...
Cat. No.: HY-N2253R
CAS No.: 17676-33-4
Neoruscogenin (Standard) is the analytical standard of Neoruscogenin. This product is intended for research and analytical applications. Neoruscogenin, a member of the steroidal sapogenin family, is a high-affinity agonist of the nuclear receptor RORα (NR1F1) (EC50 = 0.11 μM) .
loading...
    loading...
Cat. No.: HY-N1403R
CAS No.: 77-60-1
Tigogenin (Standard) is a steroidal sapogenins. Tigogenin (Standard) can inhibit adipocytic differentiation and induce osteoblastic differentiation in mouse bone marrow stromal cells. Tigogenin (Standard) can inhibit cells proliferation and induce apoptosis. Tigogenin (Standard) can be used for the researches of cancer, inflammation, immunology, metabolic and cardiovascular disease, such as mammary gland carcinoma, rheumatoid arthritis, osteoporosis and atherosclerosis .
loading...
    loading...
Cat. No.: HY-N8162
CAS No.: 65892-76-4
Soyasapogenol D is a methyl-trimethylsilyl derivative of the sapogenin .
loading...
    loading...
Cat. No.: HY-P1482R
CAS No.: 59401-28-4
Synonyms: Mating Factor α (Standard)
Sarsasapogenin (Standard) is the analytical standard of Sarsasapogenin. This product is intended for research and analytical applications. Sarsasapogenin is a sapogenin from the Chinese medical herb Anemarrhena asphodeloides Bunge, with antidiabetic, anti-oxidative, anticancer and anti-inflamatory activities.
loading...
    loading...
Cat. No.: HY-106353R
CAS No.: 126-18-1
Smilagenin (Standard) is the analytical standard of Smilagenin. This product is intended for research and analytical applications. Smilagenin (SMI) is a small-molecule steroidal sapogenin from Anemarrhena asphodeloides and Pelargonium hortorum widely used in traditional Chinese medicine for treating chronic neurodegeneration diseases . Smilagenin (SMI) improves memory of aged rats by increasing the muscarinic receptor subtype 1 (M1)-receptor density . Smilagenin (SMI) attenuates Aβ(25-35)-induced neurodegenerationvia stimulating the gene expression of brain-derived neurotrophic factor, may represents a novel therapeutic strategy for AD .
loading...
    loading...
Cat. No.: HY-146419
CAS No.: 2127403-65-8
Target:  

NF-κB COX TNF Receptor

Research Areas:  

Inflammation/Immunology

Anti-inflammatory agent 20 (compound 5a) is a potent inhibitor of NO activity. Anti-inflammatory agent 20 shows anti-inflammatory activity. Anti-inflammatory agent 20 suppresses LPS-induced inflammation via inhibiting the activation of NF-κB and MAPK signaling and thereby reducing IL-6, TNF-α, iNOS, and COX-2 upregulation .
loading...
    loading...
Cat. No.: HY-N0597R
CAS No.: 32791-84-7
Panaxatriol (Standard) is the analytical standard of Panaxatriol. This product is intended for research and analytical applications. Panaxatriol is an orally active dammarane-type tetracyclic triterpene sapogenin. Panaxatriol enhances the phosphorylation levels of Akt, insulin receptor and p70S6K in skeletal muscle. Panaxatriol reduces the mRNA expression level of Atrogin1 in skeletal muscle. Panaxatriol induces apoptosis, pre-G1 cell cycle arrest and increased intracellular ROS levels in prostate cancer cells, decreases mitochondrial membrane potential, inhibits cell migration and reduces colony formation. Panaxatriol can be used in research related to insulin resistance, myocardial ischemia/reperfusion injury and prostate cancer .
loading...
    loading...
Cat. No.: HY-N17945
CAS No.: 35882-30-5
(25S)-Ruscogenin is a steroidal sapogenin found in the tubers of Liriope spicata .
loading...
    loading...