2127403-65-8
Chemical Structure
Anti-inflammatory agent 20
- CAS No.: 2127403-65-8
- Formula:C39H66N2O8
- Molecular Weight:690.95
IUPAC Name: (3S,5R,8R,9R,10R,12R,13R,14R,17S)-12-hydroxy-17-((2S,5R)-5-(2-hydroxypropan-2-yl)-2-methyltetrahydrofuran-2-yl)-4,4,8,10,14-pentamethylhexadecahydro-1H-cyclopenta[a]phenanthren-3-yl (tert-butoxycarbonyl)glycylglycinate
InChIKey: QCIDNIHEOHAIAB-IBRXEVPMSA-N
SMILES: [H][C@@]12[C@H](CC[C@]1([C@@]3(CC[C@]4(C(C)([C@H](CC[C@@]4([C@]3(C[C@H]2O)[H])C)OC(CNC(CNC(OC(C)(C)C)=O)=O)=O)C)[H])C)C)[C@@]5(CC[C@@H](O5)C(C)(O)C)C
Biological Activity: Anti-inflammatory agent 20 (compound 5a) is a potent inhibitor of NO activity. Anti-inflammatory agent 20 shows anti-inflammatory activity. Anti-inflammatory agent 20 suppresses LPS-induced inflammation via inhibiting the activation of NF-κB and MAPK signaling and thereby reducing IL-6, TNF-α, iNOS, and COX-2 upregulation[1].
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Anti-inflammatory agent 20 | Anti-inflammatory agent 20 (compound 5a) is a potent inhibitor of NO activity. Anti-inflammatory agent 20 shows anti-inflammatory activity. Anti-inflammatory agent 20 suppresses LPS-induced inflammation via inhibiting the activation of NF-κB and MAPK signaling and thereby reducing IL-6, TNF-α, iNOS, and COX-2 upregulation. | |||||||||||||||||||||
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Keywords
