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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
21 Results for "
sialylated
" in MedChemExpress (MCE) Product Catalog:
Products (21)
21 Results for "sialylated" in MCE Product Catalog:
5
5 Cited Publications
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3FAx-Neu5Ac (Compound 8), a Sialic acid peracetylated analog, is a sialyltransferase inhibitor. 3FAx-Neu5Ac substantially reduces expression of the sialylated ligand sialyl Lewis X .
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1 Cited Publications
Cat. No.: HY-N10521
CAS No.: 35890-39-2
Category:
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Polysaccharides Endogenous metabolite Disease Research Fields Inflammation/Immunology Saccharides
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alpha-2,6-Sialyltransferase (Pd26ST) (EC 2.4.99.1) is capable of sialylating both terminal and internal galactose and N-acetylgalactosamine, which producing terminal α2,6-sialosides .
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Ganglioside GM2 is a human tumor antigen predominantly found in human tumor cells and fetal brain tissue. As a sialylated glycosphingolipid, Ganglioside GM2 is involved in processes such as cell signaling, adhesion, and motility. Ganglioside GM2 abnormal expression and accumulation are associated with tumors and neurodegenerative disorders. Ganglioside GM2 promotes tumor cell migration and invasion by directly binding to the integrin β1 receptor, activating the FAK/Src/Erk-MAPK signaling pathway, and inducing actin cytoskeleton remodeling .
Cat. No.: HY-E70284
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Keratanase II,bacillus circulans,expressed in E.coli has transglycosylation activity. Keratanase II,bacillus circulans,expressed in E.coli efficiently catalyzes the transglycosylation of α(2→3)-sialylated 6,6′-di-sulfo-LacNAc with two kinds of glycosyl acceptors, 6-sulfo-Lewis X and 6,6'-di-sulfo-LacNAc derivatives, providing Sialyl sulfo-hexasaccharide and Sialyl sulfo-pentasaccharide .
Cat. No.: HY-W540687
CAS No.: 58902-60-6
Cat. No.: HY-E70050
CAS No.: 37217-28-0
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beta-1,3-Galactosyltransferase (CgtB) (GM1-synthase) is an enzyme that required for sialylated lipooligosaccharide (LOS SIAL) production, is often used in biochemical studies. beta-1,3-Galactosyltransferase (CgtB) catalyzes the addition of a galactose molecule, which is required for GM1-like LOS SIAL structure production .
Cat. No.: HY-185060
CAS No.: 799854-49-2
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N-Acetyllactosamine-C2-NH2 (Compound β-D-Gal-(l-4)-β-D- GlcNAc-(l-4))-l-ethylamine) is a disaccharide compound and is the core backbone component for constructing sialylated glycans (sialosides) .
Cat. No.: HY-N10632
CAS No.: 64003-54-9
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Sialyllacto-N-tetraose b is a sialylated oligosaccharides. Sialyllacto-N-tetraose b naturally occurs in mammal milk .
Cat. No.: HY-N10512
CAS No.: 75645-24-8
Synonyms: Gg4
Category:
Polysaccharides Neurological Disease Endogenous metabolite Disease Research Fields Saccharides
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Cat. No.: HY-E70568
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Protease (O-glycan Cleaving) is recombinantly expressed from E.coli and contains a His tag. Protease (O-glycan Cleaving) is an O-glycan-dependent protease that digests proteins carrying mucin-type O-glycans, including sialylated substrates, glycosylated Ser and Thr residues at the N terminus. Protease (O-glycan Cleaving) digests a variety of O-glycan structures, including sialylated glycosylated core 1 and core 2 structures and Tn antigen. Protease (O-glycan Cleaving) does not digest terminally modified serine or threonine residues, nor does it digest N-glycosylation sites on glycoproteins.
Cat. No.: HY-E70147
Synonyms: EC:2.4.99.; ST3GAL6; Type 2 lactosamine α-2,3-sialyltransferase
Cat. No.: HY-152003S
CAS No.: 2692623-87-1
Cat. No.: HY-P991425
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Cat. No.: HY-D3581
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AF594 Picolyl Azide is a composite fluorescent probe formed by covalent linkage of the Alexa Fluor 594 fluorophore and the Picolyl Azide functional group via chemical bonds. AF594 Picolyl Azide contains a copper chelation domain, and through the copper-catalyzed azide-alkyne cycloaddition click chemistry reaction, it can covalently label alkyne-bearing target molecules and generate fluorescent detection signals. AF594 Picolyl Azide can be used for the detection of alkyne-modified sialylated glycoconjugates, and can also label nascent bacterial polypeptides to determine bacterial protein synthesis rates .
Cat. No.: HY-171172
CAS No.: 2493080-16-1
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GSC-718 is a CD22 inhibitor with an IC50 of 0.161 μM against mouse CD22. GSC-718 competitively blocks the binding of mouse CD22 to natural glycan ligands, and inhibits the interaction between CD22 and α2,6-sialylated ligands. GSC-718 promotes B cell proliferation and enhances antibody production. GSC-718 can be used in the research of B cell lymphoma and rheumatoid arthritis .
Cat. No.: HY-E71216
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α-2,3/8-Sialyltransferase, Campylobacter jejuni (EC 2.4.99.-) is an enzyme that transfers sialic acid to nascent oligosaccharides. α-2,3/8-Sialyltransferase, Campylobacter jejuni (EC 2.4.99.-) adds sialic acid to the terminal of sialylated glycolipids (gangliosides) or to the N- or O-linked sugar chain of glycoproteins.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
