Ganglioside GM2 

Ganglioside GM2 is a human tumor antigen (OFA-I-1). Ganglioside GM2 is the major lysosomal storage compound of Tay-Sachs disease^[1][2].

1384.68

C₆₇H₁₂₁N₃O₂₆

127663-77-8

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Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.

• [1]. Tai T, et al. Ganglioside GM2 as a human tumor antigen (OFA-I-1). Proc Natl Acad Sci U S A. 1983 Sep;80(17):5392-6.  [Content Brief]

  [2]. Anheuser S, et al. Membrane lipids regulate ganglioside GM2 catabolism and GM2 activator protein activity. J Lipid Res. 2015 Sep;56(9):1747-61.  [Content Brief]

  [3]. Nakamura K, et al. Dissection and optimization of immune effector functions of humanized anti-ganglioside GM2 monoclonal antibody. Mol Immunol. 2000 Dec;37(17):1035-46.  [Content Brief]