2. Lipids
  3. Sphingolipids
  4. Acidic Glycosphingolipids

Acidic Glycosphingolipids

Acidic Glycosphingolipids (14):

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-114456
    Ganglioside GM3 124579-05-1 99.42%
    Ganglioside GM3 is a precursor of a-, b-, and c-series gangliosides, interacts with transmembrane receptors such as the epidermal growth factor and insulin receptors, and regulates receptor functions by creating a specialized lipid environment. Ganglioside GM3 is synthesized by GM3 synthase and can be used for the research of hypercholesterolemia.
    Ganglioside GM3
  • HY-125726
    Sulfo galactosylceramide 151057-28-2 98%
    Sulfo galactosylceramide (N-Nervonoyl Sulfatide; C24:1 Sulfatide) is a glycolipid and the major sulfolipid species in mature myelin. Sulfo galactosylceramide interacts with C-type lectins and immunoglobulin-like receptors, with the highest affinity for LMIR5. Sulfo galactosylceramide induces MCP-1 production by basophils but not mast cells, and increases NFAT activation via LMIR5. Sulfo galactosylceramide alleviates symptoms and improves survival in a mouse model of chronic relapsing-remitting experimental autoimmune encephalomyelitis (EAE), and reduces inflammatory lesions and the number of infiltrating mononuclear cells in the lumbar spinal cord of EAE mice.
    Sulfo galactosylceramide
  • HY-165180
    Lyso-sulfatide (bovine) sodium 70005-46-8
    Lyso-sulfatide (bovine) sodium is a phospholipid component derived from sphingolipid catabolism and a potent factor Xa inhibitor and anticoagulant. Lyso-sulfatide (bovine) sodium binds directly to factor Xa and inhibits prothrombin activation mediated by the prothrombinase complex, thereby prolonging factor Xa-induced plasma clotting time and suppressing thrombin generation. Lyso-sulfatide (bovine) sodium serves as a reliable lipid membrane mimic for studying cell membrane structure, function, and molecular interactions.
    Lyso-sulfatide (bovine) sodium
  • HY-148747
    Ganglioside GD3 (d18:1/12:0) 138749-26-5
    Ganglioside GD3 (d18:1/12:0) is a type of glycosphingolipid, the d18:1 indicates the sphingosine base, and the 12:0 represents the fatty acid part which is lauric acid. Ganglioside GD3 (d18:1/12:0) is a crucial intermediate in the biosynthesis pathway of gangliosides and is mainly found in the brain tissues of mammals. Ganglioside GD3 (d18:1/12:0) plays significant roles in development, cell signal transduction, and various diseases.
    Ganglioside GD3 (d18:1/12:0)
  • HY-N15820
    C18:0 GM1(Neu5Gc) Ceramide (d18:1/18:0) 3056013-75-0
    C18:0 GM1(Neu5Gc) Ceramide (d18:1/18:0) is a ganglioside.
    C18:0 GM1(Neu5Gc) Ceramide (d18:1/18:0)
  • HY-N15844
    C24:1 GM3 Ceramide (d18:1/24:1) 1408313-38-1
    C24:1 GM3 Ceramide (d18:1/24:1) is a globoside that can be used to prepare lipid nanoparticles for drug delivery.
    C24:1 GM3 Ceramide (d18:1/24:1)
  • HY-171936
    Ganglioside GM1 ammonium 1329115-44-7
    Ganglioside GM1 (ammonium) is a monosialylated ganglioside and the prototypic ganglioside for those containing one sialic acid residue. Ganglioside GM1 (ammonium) is one of the most abundant gangliosides in the brain which provides neuroprotection. Ganglioside GM1 (ammonium) exhibits anti-inflammatory property. Ganglioside GM1 (ammonium) has a well-balanced amphiphilic behavior. Ganglioside GM1 (ammonium) can reduce the fluidity of the plasma membrane that implies a retention and enrichment of the ganglioside in specific membrane domains that are called lipid rafts. Ganglioside GM1 (ammonium) can modify the process of differentiation, amplifies responses to neurotrophic factors, protects against excitatory amino acid-related neurotoxicity. Ganglioside GM1 (ammonium) can alleviate acute nerve cell damage through blocking cytotoxicity and potentiating neurotophic factors. Ganglioside GM1 (ammonium) can be studied in neurodegenerative diseases such as Alzheimer’s disease.
    Ganglioside GM1 ammonium
  • HY-145535
    Tetracosanoyl-sulfatide 151122-71-3
    Tetracosanoyl-sulfatide is an endogenous metabolite present in Urine that can be used for the research of Mild Metachromatic Leukodystrophy.
    Tetracosanoyl-sulfatide
  • HY-153869
    18:0 (2R-OH) Sulfo GalCer ammonium 2260670-26-4
    18:0 (2R-OH) Sulfo GalCer (ammonium) is a glycosphingolipid.
    18:0 (2R-OH) Sulfo GalCer ammonium
  • HY-179782
    18:0 (2S-OH) Sulfo GalCer ammonium 2260670-28-6
    18:0 (2S-OH) Sulfo GalCer (ammonium) is a glycosphingolipid.
    18:0 (2S-OH) Sulfo GalCer ammonium
  • HY-165650A
    C16 Ganglioside GM1 (d18:1/16:0) ammonium
    C16 Ganglioside GM1 (d18:1/16:0) (C16-GM1) ammonium is a member of the ganglioside family containing saturated C16:0 acyl chains. C16 Ganglioside GM1 (d18:1/16:0) ammonium serves as a functional receptor for Cholera toxin (HY-P1446) B subunit, while showing reduced efficiency in both transcytosis and retrograde pathways. C16 Ganglioside GM1 (d18:1/16:0) ammonium can be used for diarrheal diseases research.
    C16 Ganglioside GM1 (d18:1/16:0) ammonium
  • HY-165650
    C16 Ganglioside GM1 (d18:1/16:0) 165615-97-4
    C16 Ganglioside GM1 (d18:1/16:0) (C16-GM1) is a member of the ganglioside family containing saturated C16:0 acyl chains. C16 Ganglioside GM1 (d18:1/16:0) serves as a functional receptor for Cholera toxin (HY-P1446) B subunit, while showing reduced efficiency in both transcytosis and retrograde pathways. C16 Ganglioside GM1 (d18:1/16:0) can be used for diarrheal diseases research.
    C16 Ganglioside GM1 (d18:1/16:0)
  • HY-165641
    N-Octadecanoyl-sulfatide 244215-65-4
    N-Octadecanoyl-sulfatide is an ester product.
    N-Octadecanoyl-sulfatide
  • HY-165880
    Palmitoyl sulfatide 89771-78-8
    Palmitoyl sulfatide is an ester product.
    Palmitoyl sulfatide