Disialyloctasaccharide
Based on 1 Customer Validation
Disialyloctasaccharide is a class of biochemical reagents used in glycobiology research. Disialyloctasaccharide serves as an internal standard for serum glycomics analysis, including absolute quantification of N-glycans and quantification of serum sialylated glycans via MALDI-TOF/MS. Disialyloctasaccharide can be applied to research related to hepatocellular carcinoma.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度 : 99.29%
- CAS 番号: 58902-60-6
- 分子式: C76H125N5O57
- 分子量:2020.81
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保管条件:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
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溶剤 & 溶解度
- プロトコル
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
製品説明
体外実験
Disialyloctasaccharide (20 mg/mL Hydralazine (HY-B0464A); 35 min), when derivatized with hydralazine as a reactive matrix, produces a labeled ion with an S/N ratio of 415, demonstrating enhanced detection sensitivity in negative-mode MALDI-MS compared to non-derivatized analysis with 9-AA matrix[2].
Disialyloctasaccharide serves as an effective internal standard for serum sialylated glycan quantification, with the assay showing an RSD of 12.17% for SG29 in human serum[5].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Further protocols information, click here.
化学情報
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CAS 番号 58902-60-6
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性状 Solid
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分子量 2020.81
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分子式 C76H125N5O57
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Color White to off-white
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SMILES
OC[C@@H](O[C@H]([C@@H]([C@H]1O)NC(C)=O)O[C@@H]2[C@H](O[C@@H]([C@H]([C@@H]2O)O)CO)O[C@@H]3[C@@H]([C@@H](O[C@@H]([C@H]3O)CO[C@@H]4[C@H]([C@H]([C@@H]([C@H](O4)CO)O)O)O[C@H]5[C@@H]([C@H]([C@@H]([C@H](O5)CO)O[C@@H]6O[C@@H]([C@@H]([C@@H]([C@H]6O)O)O)CO[C@]7(O[C@@]([C@@H]([C@H](C7)O)NC(C)=O)([H])[C@H](O)[C@H](O)CO)C(O)=O)O)NC(C)=O)O[C@H]([C@H](O)CO)[C@H](O)[C@H](C=O)NC(C)=O)O)[C@H]1O[C@@H]([C@@H]([C@H]([C@H]8O)O)O)O[C@@H]8CO[C@]9(O[C@@]([C@@H]([C@H](C9)O)NC(C)=O)([H])[C@H](O)[C@H](O)CO)C(O)=O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
溶剤 & 溶解度
体外:
H2O : 50 mg/mL (24.74 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
プロトコル
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Liver Cancer Modeling
Liver cancer can be classified into primary liver cancer and secondary liver cancer. Secondary liver cancer is the metastatic liver cancer. Primary liver cancer includes hepatocellular carcinoma (HCC), intrahepatic cholangiocarcinoma (ICC) and fibrolamellar HCC, of which HCC is the most common form, accounting for approximately 90% of primary liver cancers[1]. HCC mouse models include chemical agent-induced models, transplanted tumor models, and genetic engineered models.
純度とドキュメンテーション
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データシート (289 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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取扱説明書 (2659 KB)
参考文献
[1]. Opdenakker G, et al. Concepts and principles of glycobiology. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 1993 Nov;7(14):1330-7. [Content Brief]
[3]. Mahmoud ME, et al. Identification of serum N-glycoproteins as a biological correlate underlying chronic stress response in mice. Molecular biology reports. 2019 Jun;46(3):2733-2748. [Content Brief]
[4]. Gebrehiwot AG, et al. Exploring serum and immunoglobulin G N-glycome as diagnostic biomarkers for early detection of breast cancer in Ethiopian women. BMC cancer. 2019 Jun 17;19(1):588. [Content Brief]
[5]. Zhu L, et al. Profiling of aberrant sialylated N-glycans in hepatocellular carcinoma by liquid chromatography mass spectrometry. Clinica chimica acta; international journal of clinical chemistry. 2024 Mar 01;555:117827. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
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| H2O | 1 mM | 0.4949 mL | 2.4743 mL | 4.9485 mL | 12.3713 mL |
| 5 mM | 0.0990 mL | 0.4949 mL | 0.9897 mL | 2.4743 mL | |
| 10 mM | 0.0495 mL | 0.2474 mL | 0.4949 mL | 1.2371 mL | |
| 15 mM | 0.0330 mL | 0.1650 mL | 0.3299 mL | 0.8248 mL | |
| 20 mM | 0.0247 mL | 0.1237 mL | 0.2474 mL | 0.6186 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Disialyloctasaccharide 関連分類
HY-W540687 関連分類
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