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Cat. No.: HY-171172

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GSC-718

GSC-718 is a synthetic sialoside and is a ligand mimic for CD22. GSC-718 is a potent CD22 inhibitor with an IC₅₀ of 0.161μM for mCD22. GSC-718 promote the proliferation of B cells and enhance antibody production. GSC-718 can be used for researches of B-cell lymphoma and rheumatoid arthritis.

For research use only. We do not sell to patients.

CAS No.: 2493080-16-1
Formula: C₃₂H₃₅N₂NaO₁₁
Molecular Weight:646.62

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (268 KB)

GSC-718 Chemical Structure

CAS No.: 2493080-16-1

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Top Publications Citing

Use of MCE Products

Antibody-Drug Conjugates

One-stop solution for XDC (ADC/PDC/RDC/ApDC/FDC/ISAC/VDC/SMDC)

Biological Activity

Description

Chemical Information

CAS No. 2493080-16-1
Molecular Weight 646.62
Formula C₃₂H₃₅N₂NaO₁₁
SMILES

O=C(O[Na])[C@@]1(O[C@@]([C@@H]([C@H](C1)O)NC(CO)=O)([H])[C@H](O)[C@H](O)CNC(CC2=CC=C(C3=CC=C(C=C3)O)C=C2)=O)OCC4=CC=CC=C4
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (268 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Suganuma Y, et al. Improved synthesis of CD22-binding sialosides and its application for further development of potent CD22 inhibitors. Glycoconj J. 2023 Apr;40(2):225-246. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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