1 Result for "

superhelical PM2 DNA

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "superhelical PM2 DNA" in MCE Product Catalog:

Cat. No.: HY-130050
CAS No.: 75580-37-9
Synonyms: BBM-928 A
Category:  

Microorganisms Antibiotics

Target:  

Antibiotic HIV

Luzopeptin A (BBM-928 A) is an actinoleukin-like antitumor antibiotic. Luzopeptin A is a bifunctional DNA intercalator which can interact with isolated DNA molecules. Luzopeptin A induces an unwinding-rewinding process of the closed superhelical PM2 DNA. Luzopeptin A is active against HIV-1 and HIV-2 reverse transcriptase with IC50s of 7 nM and 68 nM for HIV-1 RT and HIV-2 RT, respectively .
loading...
    loading...