38 Results for "

thiazide

" in MedChemExpress (MCE) Product Catalog:
Products (38)

38 Results for "thiazide" in MCE Product Catalog:

13
13 Publications Verification
Cat. No.: HY-108896
CAS No.: 138614-30-9
Purity:  99.85%
Synonyms: HOE 140 acetate
Target:  

Bradykinin Receptor

Research Areas:  

Inflammation/Immunology

Icatibant acetate (HOE-140 acetate) is a potent and specific peptide antagonist of bradykinin B2 receptor with an IC50 and Ki of 1.07 nM and 0.798 nM respectively .
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8
8 Cited Publications
Cat. No.: HY-B0252
CAS No.: 58-93-5
Synonyms: HCTZ
Hydrochlorothiazide (HCTZ), an orally active diuretic agent of the thiazide class, inhibits transforming TGF-β/Smad signaling pathway. Hydrochlorothiazide has direct vascular relaxant effects via opening of the calcium-activated potassium (KCA) channel. Hydrochlorothiazide improves cardiac function, reduces fibrosis and has antihypertensive effect .
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2
2 Cited Publications
Cat. No.: HY-B0235
CAS No.: 133-67-5
Target:  

Carbonic Anhydrase

Research Areas:  

Metabolic Disease

Trichlormethiazide is an orally active thiazide diuretic, with antihypertensive effect. Trichlormethiazide increases urine volume (UV), Na and K excretion and tends to improve the depressed creatinine clearance (CCRE) in acute renal failure rats model .
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1
1 Cited Publications
Cat. No.: HY-15833
CAS No.: 77-36-1
Purity:  99.76%
Chlorthalidone is a thiazide-like diuretic used to treat hypertension.
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1
1 Cited Publications
Cat. No.: HY-B1477
CAS No.: 636-54-4
Clopamide is an orally active thiazide-like diuretic agent that inhibits the sodium-coupled chloride cotransporter SLC12A3. Clopamide has the potential for hypertension and cardiac failure research .
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Cat. No.: HY-118472
CAS No.: 86541-78-8
Purity:  99.54%
Synonyms: CGS 14831
Benazeprilat is an orally active and the active metabolite of benazepril, a carboxyl-containing ACE inhibitor with antihypertensive activity. Benazepril is a well-established antihypertensive agent, both in monoresearch and in combination with other classes of drugs including thiazide diuretics and calcium channel blockers. Benazepril is a first-line research in reducing various pathologies associated with CV risk and secondary end-organ damage .
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Cat. No.: HY-P10303
CAS No.: 2767993-86-0
Synonyms: Cyclo[RGDfK(Azide)]
Research Areas:  

Others

Cyclo[Arg-Gly-Asp-D-Phe-Lys(Azide)] is the derivative of Cyclo(-RGDfK) (HY-P0023). Cyclo[Arg-Gly-Asp-D-Phe-Lys(Azide)] is a click chemistry reagent containing an azide group. Click chemistry has great potential for use in binding between nucleic acids, lipids, proteins, and other molecules, and has been used in many research fields because of its beneficial characteristics, including high yield, high specificity, and simplicity .
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Cat. No.: HY-W011240
CAS No.: 135-09-1
Synonyms: Methforylthiazidine; Rontyl
Hydroflumethiazide (Methforylthiazidine) is an orally active and potent thiazide diuretic. Hydroflumethiazide possesses the ability to directly stimulate A cell secretion in the normal and alloxan diabetic pancreas .
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Cat. No.: HY-B0252S1
CAS No.: 1190006-03-1
Synonyms: HCTZ-13C,d2
Hydrochlorothiazid- 13C,d2 is the 13C- and deuterium labeled Hydrochlorothiazide. Hydrochlorothiazide (HCTZ), an orally active diuretic agent of the thiazide class, inhibits transforming TGF-β/Smad signaling pathway. Hydrochlorothiazide has direct vascular relaxant effects via opening of the calcium-activated potassium (KCA) channel. Hydrochlorothiazide improves cardiac function, reduces fibrosis and has antihypertensive effect .
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Cat. No.: HY-B1254
CAS No.: 5588-16-9
Synonyms: Althiazide
Target:  

Others

Research Areas:  

Cardiovascular Disease

Altizide (Althiazide) is an orally active diuretic. Altizide can be used in studies of oedema and hypertension .
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Cat. No.: HY-B0252R
CAS No.: 58-93-5
Synonyms: HCTZ (Standard)
Hydrochlorothiazide (Standard) is the analytical standard of Hydrochlorothiazide. This product is intended for research and analytical applications. Hydrochlorothiazide (HCTZ), an orally active diuretic agent of the thiazide class, inhibits transforming TGF-β/Smad signaling pathway. Hydrochlorothiazide has direct vascular relaxant effects via opening of the calcium-activated potassium (KCA) channel. Hydrochlorothiazide improves cardiac function, reduces fibrosis and has antihypertensive effect .
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Cat. No.: HY-15833S
CAS No.: 1794941-44-8
Purity:  97.50%
Chlorthalidone-d4 is the deuterium labeled Chlorthalidone. Chlorthalidone is a thiazide-like diuretic used to treat hypertension.
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Cat. No.: HY-B0252S
CAS No.: 1219798-89-6
Synonyms: HCTZ-d2
Hydrochlorothiazid-d2 is the deuterium labeled Hydrochlorothiazide. Hydrochlorothiazide (HCTZ), an orally active diuretic agent of the thiazide class, inhibits transforming TGF-β/Smad signaling pathway. Hydrochlorothiazide has direct vascular relaxant effects via opening of the calcium-activated potassium (KCA) channel. Hydrochlorothiazide improves cardiac function, reduces fibrosis and has antihypertensive effect .
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Cat. No.: HY-W663740
CAS No.: 16339-07-4
Synonyms: MNP; MeNP; N-Methyl-N'-nitrosopiperazine
Research Areas:  

Others

1-Methyl-4-nitrosopiperazine (MNP; MeNP;N-Methyl-N'-nitrosopiperazine) is a potential impurity in sartans, non-steroidal anti-inflammatory drugs (NSAIDs), and thiazide diuretics .
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Cat. No.: HY-B0562
CAS No.: 135-07-9
Methyclothiazide is an orally active antihypertensive agent and a diuretic agent. Methyclothiazide leads to a reduction of the vascular response to the action of endogenous vasoconstricting stimuli, such as Norepinephrine (HY-13715). Methyclothiazide is against voltage-dependent Ca-channel (VDCC) activity in vitro .
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Cat. No.: HY-B0235R
CAS No.: 133-67-5
Research Areas:  

Metabolic Disease

Trichlormethiazide (Standard) is the analytical standard of Trichlormethiazide. This product is intended for research and analytical applications. Trichlormethiazide is an orally active thiazide diuretic, with antihypertensive effect. Trichlormethiazide increases urine volume (UV), Na and K excretion and tends to improve the depressed creatinine clearance (CCRE) in acute renal failure rats model .
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Cat. No.: HY-B0252S3
CAS No.: 2140316-81-8
Synonyms: HCTZ-15N2,13C,d2
Hydrochlorothiazide- 15N2, 13C,d2 is 15N and deuterated labeled Hydrochlorothiazide (HY-B0252). Hydrochlorothiazide (HCTZ), an orally active diuretic agent of the thiazide class, inhibits transforming TGF-β/Smad signaling pathway. Hydrochlorothiazide has direct vascular relaxant effects via opening of the calcium-activated potassium (KCA) channel. Hydrochlorothiazide improves cardiac function, reduces fibrosis and has antihypertensive effect .
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Cat. No.: HY-Z8643
CAS No.: 402824-96-8
Research Areas:  

Others

HCTZ-CH2-HCTZ is an isomer of HCTZ (HY-B0252). Hydrochlorothiazide (HCTZ), an orally active diuretic agent of the thiazide class, inhibits transforming TGF-β/Smad signaling pathway .
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Cat. No.: HY-126179
CAS No.: 20287-37-0
Purity:  99.58%
Synonyms: MG-13054
Fenquizone (MG-13054) is an orally active diuretic. Fenquizone acts primarily on the diluting segment of the nephron cortex, similar to thiazide diuretics. Fenquizone demonstrates diuretic and natriuretic potency and duration of action comparable to thiazide diuretics but weaker than loop diuretics.​ Fenquizone reduces CH₂O without affecting TCH₂O, does not increase calcium/phosphate excretion, and has no loop or collecting duct effects. Fenquizone is used in the study of edema and hypertension .
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Cat. No.: HY-B0235A
CAS No.: 91996-54-2
Target:  

Carbonic Anhydrase

Research Areas:  

Metabolic Disease

Trichlormethiazide sodium is an orally active thiazide diuretic, with antihypertensive effect. Trichlormethiazide sodium increases urine volume (UV), Na and K excretion and tends to improve the depressed creatinine clearance (CCRE) in acute renal failure rats model .
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