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transdermal delivery

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-B1829A
    Dexamethasone phosphate disodium
    10+ Cited Publications

    Dexamethasone 21-phosphate disodium

    		 Glucocorticoid Receptor TGF-β Receptor Interleukin Related Neurological Disease Inflammation/Immunology
    Dexamethasone phosphate (Dexamethasone 21-phosphate) disodium is a prodrug form of the glucocorticoid Dexamethasone (HY-14648). Dexamethasone phosphate disodium is produced by introducing a phosphate ester group at the 21-position of the Dexamethasone molecule, forming a salt with sodium ions, thereby significantly improving water solubility. Dexamethasone phosphate disodium inhibits LPS (HY-D1056)-induced degradation of IRAK-1 and IRAK-4, and blocks LPS-induced activation of TRAF6, p-TAK1 and p-JNK. Dexamethasone phosphate disodium inhibits the secretion of RANTES, TGF-β1 and NO, promotes the production of MIP-1α and IL-10, and blocks microglial migration. Dexamethasone phosphate disodium is almost completely converted to Dexamethasone in rat blood, and supports transdermal delivery via iontophoresis. Dexamethasone phosphate disodium can be used in research related to steroid-dependent ulcerative colitis, chemotherapy-induced vomiting, allergic asthma and acute colitis (inflammatory bowel disease) .
    Dexamethasone phosphate disodium
  • HY-W723152
    Poly(D,L-lactide-co-glycolide)

    		Drug Intermediate Inflammation/Immunology
    Poly(D,L-lactide-co-glycolide) is a biodegradable polymer copolymer. Poly(D,L-lactide-co-glycolide) undergoes degradation through ester bond hydrolysis into lactic acid and glycolic acid. These two products can be naturally eliminated through metabolism in the body (such as the tricarboxylic acid cycle), without the risk of long-term accumulation. Poly(D,L-lactide-co-glycolide) can be used in medical sutures, implants, and drug delivery systems .
    Poly(D,L-lactide-co-glycolide)
  • HY-W250721A
    Carbomer 940

    CBM 940

    		 Biochemical Assay Reagents Others
    Carbomer 940 (CBM 940) is an acrylic polymer with high viscosity, good thermal stability and histocompatibility. Carbomer 940 serves as a transdermal drug delivery carrier and an external gel matrix. Carbomer 940 has no cytotoxicity, and it can also improve blood supply in the stasis zone of burns and promote wound repair. Carbomer 940 is applicable to pharmaceutical research .
    Carbomer 940
  • HY-W141881
    N-Lauroylsarcosine

    		Environmental Pollutants Biochemical Assay Reagents HSV Infection
    N-lauroylsarcosine is an anionic surfactant. N-lauroylsarcosine has antiviral activity against HSV-2 strain 333 and HSV-1 strain F. N-lauroylsarcosine synergistically increases skin permeability with 25-50% ethanol. N-lauroylsarcosine can be used to study HSV-2 infection .
    N-Lauroylsarcosine
  • HY-124190
    Isopropyl myristate

    		Environmental Pollutants Biochemical Assay Reagents Others
    Isopropyl myristate (IPM) is the ester of isopropyl alcohol and myristic acid. Isopropyl myristate is used for transdermal delivery of some compounds. Isopropyl myristate is a polar emollient and is used in cosmetic and topical medicinal preparations where good absorption into the skin is desired .
    Isopropyl myristate
  • HY-W129513
    Sorbitan monopalmitate

    		Biochemical Assay Reagents Others
    Sorbitan monopalmitate is a food-grade, non-ionic emulsifier that exhibits oral activity. Sorbitan monopalmitate functions as a crystallization modifier, promoting the aggregation of spherical mango butter crystals, introducing lattice defects, and regulating the crystallization rate of mango butter. Sorbitan monopalmitate serves as a component of precursor vesicle gels, enabling the controlled and sustained release of drugs and facilitating the preparation of stable transdermal delivery formulations .
    Sorbitan monopalmitate
  • HY-W243303O
    Poly(acrylic acid) (MW 1250000) (viscous liquid)

    		Environmental Pollutants Biochemical Assay Reagents Cancer
    Poly(acrylic acid) (Mv 1250000) (viscous liquid) is a polyacrylic acid with a molecular weight of 1250000 (an anionic polymer), which can be used as a corrosion inhibitor and surface stabilizer. Poly(acrylic acid) can be used to construct an anionic nanogel to encapsulate positively charged enzymes and to modify MoS₂ nanoparticles to build a transdermal drug delivery system .
    Poly(acrylic acid) (MW 1250000) (viscous liquid)
  • HY-14826
    Tilivapram

    AVE8112

    		 Phosphodiesterase (PDE) Neurological Disease
    Tilivapram (AVE8112) is an orally active PDE4 inhibitor with procognitive effects. Tilivapram exhibits in vivo efficacy and improves processing speed and psychomotor speed. Oral administration of tilivapram may induce dose-related adverse reactions such as nausea and dizziness, but transdermal delivery enables slow, controlled elevation of plasma concentrations, thereby significantly reducing gastrointestinal discomfort and dizziness. Tilivapram is applicable to research related to neuropsychiatric disorders .
    Tilivapram
  • HY-P1565
    Transdermal Peptide Disulfide

    TD 1 Disulfide(peptide)

    		 Na+/K+ ATPase Inflammation/Immunology
    Transdermal Peptide Disulfide (TD 1 Disulfide(peptide)) is a 11-amino acid peptide, binds toNa +/K +-ATPase beta-subunit (ATP1B1), and mainly interacts with the C-terminus of ATP1B1. Transdermal Peptide Disulfide can enhance the transdermal delivery of many macromolecules .
    Transdermal Peptide Disulfide
  • HY-P1565A
    Transdermal Peptide Disulfide TFA

    TD 1 Disulfide(peptide) TFA

    		 Na+/K+ ATPase Others
    Transdermal Peptide Disulfide TFA (TD 1 Disulfide(peptide) TFA) is a 11-amino acid peptide, binds to Na +/K +-ATPase beta-subunit (ATP1B1), and mainly interacts with the C-terminus of ATP1B1. Transdermal Peptide Disulfide TFA can enhance the transdermal delivery of many macromolecules .
    Transdermal Peptide Disulfide TFA
  • HY-B1829AR
    Dexamethasone phosphate disodium (Standard)

    Dexamethasone 21-phosphate disodium (Standard)

    		 Glucocorticoid Receptor Reference Standards Interleukin Related TGF-β Receptor Neurological Disease Metabolic Disease Inflammation/Immunology
    Dexamethasone phosphate (Dexamethasone 21-phosphate) disodium (Standard) is the analytical standard of Dexamethasone phosphate disodium (HY-B1829A). This product is intended for research and analytical applications. Dexamethasone phosphate (Dexamethasone 21-phosphate) disodium is a prodrug form of the glucocorticoid Dexamethasone (HY-14648). Dexamethasone phosphate disodium is produced by introducing a phosphate ester group at the 21-position of the Dexamethasone molecule, forming a salt with sodium ions, thereby significantly improving water solubility. Dexamethasone phosphate disodium inhibits LPS (HY-D1056)-induced degradation of IRAK-1 and IRAK-4, and blocks LPS-induced activation of TRAF6, p-TAK1 and p-JNK. Dexamethasone phosphate disodium inhibits the secretion of RANTES, TGF-β1 and NO, promotes the production of MIP-1α and IL-10, and blocks microglial migration. Dexamethasone phosphate disodium is almost completely converted to Dexamethasone in rat blood, and supports transdermal delivery via iontophoresis. Dexamethasone phosphate disodium can be used in research related to steroid-dependent ulcerative colitis, chemotherapy-induced vomiting, allergic asthma and acute colitis (inflammatory bowel disease).
    Dexamethasone phosphate disodium (Standard)
  • HY-W243303D
    Poly(acrylic acid) (MW 1250000)

    		Environmental Pollutants Biochemical Assay Reagents Others
    Poly(acrylic acid) (MW 1250000) is a polyacrylic acid with a molecular weight of 1250000 (an anionic polymer), which can be used as a corrosion inhibitor and surface stabilizer. Poly(acrylic acid) can be used to construct an anionic nanogel to encapsulate positively charged enzymes and to modify MoS2 nanoparticles to build a transdermal drug delivery system .
    Poly(acrylic acid) (MW 1250000)
  • HY-B1829
    Dexamethasone phosphate
    10+ Cited Publications

    Dexamethasone 21-phosphate

    		 Glucocorticoid Receptor TGF-β Receptor Interleukin Related Neurological Disease Inflammation/Immunology
    Dexamethasone phosphate (Dexamethasone 21-phosphate) is a prodrug form of the glucocorticoid Dexamethasone (HY-14648). Dexamethasone phosphate is prepared by introducing a phosphate ester group to the hydroxyl group at position 21 of the Dexamethasone molecule. Dexamethasone phosphate inhibits LPS (HY-D1056)-induced degradation of IRAK-1 and IRAK-4, and blocks LPS-induced activation of TRAF6, p-TAK1 and p-JNK. Dexamethasone phosphate inhibits the secretion of RANTES, TGF-β1 and NO, promotes the production of MIP-1α and IL-10, and blocks microglial migration. Dexamethasone phosphate is almost completely converted to Dexamethasone in rat blood, and supports transdermal delivery via iontophoresis. Dexamethasone phosphate can be used in research related to steroid-dependent ulcerative colitis, chemotherapy-induced vomiting, allergic asthma and acute colitis (inflammatory bowel disease) .
    Dexamethasone phosphate
  • HY-W020576
    Rivastigmine metabolite

    NAP 226-90

    		 Drug Metabolite Others Neurological Disease
    Rivastigmine metabolite (NAP 226-90) is a metabolite produced by the hydrolysis of Rivastigmine (HY-17368) . Rivastigmine metabolite serves as a surrogate marker to track the bioavailability, metabolic extent, and transdermal patch delivery rate of Rivastigmine .
    Rivastigmine metabolite
  • HY-W050154R
    Kojic acid (Standard)

    		Reference Standards Parasite Tyrosinase NF-κB CDK Infection Inflammation/Immunology Cancer
    Kojic acid (Standard) is the analytical standard of Kojic acid. This product is intended for research and analytical applications. Kojic acid is a substance produced by Aspergillus oryzae, with various biological activities including antitumor, insecticidal, antibacterial, antioxidant, and radioprotective effects. Kojic acid exhibits tyrosinase inhibition activity by capturing copper ions that bind to the active site of tyrosinase, preventing its activation. Tyrosinase is a key enzyme in the biosynthesis of melanin, so kojic acid can block melanin production. Additionally, kojic acid shows potential inhibition of NF-κB activity in human keratinocytes, which may also be related to the anti-melanogenic effect induced by kojic acid. Kojic acid is effective when administered orally and can also be absorbed transdermally. Nano-carrier systems prepared with kojic acid demonstrate effective delivery of anticancer drugs. Kojic acid holds promise for research in cancer, infectious diseases, and skin whitening among other fields .
    Kojic acid (Standard)
  • HY-124190R
    Isopropyl myristate (Standard)

    		Biochemical Assay Reagents Reference Standards Others
    Isopropyl myristate (Standard) is the analytical standard of Isopropyl myristate. This product is intended for research and analytical applications. Isopropyl myristate (IPM) is the ester of isopropyl alcohol and myristic acid. Isopropyl myristate is used for transdermal delivery of some compounds. Isopropyl myristate is a polar emollient and is used in cosmetic and topical medicinal preparations where good absorption into the skin is desired .
    Isopropyl myristate (Standard)
  • HY-W020576R
    Rivastigmine metabolite (Standard)

    NAP 226-90 (Standard)

    		 Reference Standards Drug Metabolite Neurological Disease
    Rivastigmine metabolite (Standard) is the analytical standard of Rivastigmine metabolite. This product is intended for research and analytical applications. Rivastigmine metabolite (NAP 226-90) is a metabolite produced by the hydrolysis of Rivastigmine (HY-17368) . Rivastigmine metabolite serves as a surrogate marker to track the bioavailability, metabolic extent, and transdermal patch delivery rate of Rivastigmine .
    Rivastigmine metabolite (Standard)
  • HY-B1829R
    Dexamethasone phosphate (Standard)

    Dexamethasone 21-phosphate (Standard)

    		 Glucocorticoid Receptor Reference Standards TGF-β Receptor Interleukin Related Neurological Disease Inflammation/Immunology
    Dexamethasone phosphate (Standard) (Dexamethasone 21-phosphate (Standard)) is the analytical standard of Dexamethasone phosphate (HY-B1829). This product is intended for research and analytical applications. Dexamethasone phosphate (Dexamethasone 21-phosphate) is a prodrug form of the glucocorticoid Dexamethasone (HY-14648). Dexamethasone phosphate is prepared by introducing a phosphate ester group to the hydroxyl group at position 21 of the Dexamethasone molecule. Dexamethasone phosphate inhibits LPS (HY-D1056)-induced degradation of IRAK-1 and IRAK-4, and blocks LPS-induced activation of TRAF6, p-TAK1 and p-JNK. Dexamethasone phosphate inhibits the secretion of RANTES, TGF-β1 and NO, promotes the production of MIP-1α and IL-10, and blocks microglial migration. Dexamethasone phosphate is almost completely converted to Dexamethasone in rat blood, and supports transdermal delivery via iontophoresis. Dexamethasone phosphate can be used in research related to steroid-dependent ulcerative colitis, chemotherapy-induced vomiting, allergic asthma and acute colitis (inflammatory bowel disease).
    Dexamethasone phosphate (Standard)
  • HY-178412S
    Isopropyl myristate-d27

    		Isotope-Labeled Compounds Biochemical Assay Reagents Others
    Isopropyl myristate-d27 is the deuterium labeled Isopropyl myristate (HY-124190). Isopropyl myristate (IPM) is the ester of isopropyl alcohol and myristic acid. Isopropyl myristate is used for transdermal delivery of some compounds. Isopropyl myristate is a polar emollient and is used in cosmetic and topical medicinal preparations where good absorption into the skin is desired .
    Isopropyl myristate-d27
  • HY-W020576S
    Rivastigmine metabolite-d6

    NAP 226-90-d6

    		 Isotope-Labeled Compounds Drug Metabolite Others
    Rivastigmine metabolite-d6 (NAP 226-90-d6) is a deuterated form of Rivastigmine metabolite. Rivastigmine metabolite (NAP 226-90) is a metabolite produced by the hydrolysis of Rivastigmine (HY-17368) . Rivastigmine metabolite serves as a surrogate marker to track the bioavailability, metabolic extent, and transdermal patch delivery rate of Rivastigmine .
    Rivastigmine metabolite-d6

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