12 Results for "

van der Waals interactions

" in MedChemExpress (MCE) Product Catalog:
Products (12)

12 Results for "van der Waals interactions" in MCE Product Catalog:

Cat. No.: HY-W020780
CAS No.: 724722-89-8
Synonyms: mPEG5000-Maleimide
mPEG5000-Mal (mPEG5000-Maleimide) is a PEG-derived selective covalent binding agent for sulfhydryl groups (RSGs), which can form irreversible thioether bonds with sulfhydryl groups under near-neutral conditions via the maleimide group. The mechanism of action of mPEG5000-Mal can be divided into two categories: firstly, as an enzyme modifier, it binds to target proteins through hydrophobic interactions, hydrogen bonds, and van der Waals forces, altering the protein's secondary structure; secondly, as a nanoparticle surface modifier, it covalently binds to sulfhydryl groups on the surface of red blood cells, changing the surface properties and morphology of the red blood cells, leading to their phagocytosis by macrophages of the reticuloendothelial system. mPEG5000-Mal can react with free cysteine in proteins, increasing the apparent molecular weight of the modified protein by 10-15 kDa for detection purposes. mPEG5000-Mal can enhance the thermal stability and catalytic activity of enzymes, and improve the macrophage targeting of nanoparticles, enabling targeted drug delivery. mPEG5000-Mal can be applied in enzyme engineering research in the food industry and in oncology, assisting radiotherapy by inhibiting tumor-associated macrophage infiltration and enhancing anti-tumor immune responses .
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Cat. No.: HY-W087904
CAS No.: 5989-81-1
Synonyms: α-D-Lactose hydrate
α-Lactose hydrate (α-D-Lactose (hydrate)) is the primary carbohydrate in the milk of most mammals. α-Lactose hydrate consists of glucose and galactose and exists in two isomeric forms, α and β. α-Lactose hydrate has numerous applications in the food and pharmaceutical industries, such as serving as a bulking or agglomerating agent, and a diluent for pigments, flavors or enzymes .
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Cat. No.: HY-W127329
CAS No.: 106-14-9
Category:  

Microorganisms

12-Hydroxystearic acid is a structurally simple and cost-effective low molecular weight organogelator, and its metal salts and derivatives find roles in many important applications .
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Cat. No.: HY-W013396
CAS No.: 619-58-9
Research Areas:  

Others

4-Iodobenzoic acid is a 4-iodobenzoic acid that crystallizes as a dimer in the monoclinic space group P21/n, with a phase transition center temperature of 230.77 K, and exhibits intermolecular iodine-iodine van der Waals interactions. 4-Iodobenzoic acid can be used in studies of hydrogen bonding, crystal packing and solid-state phase transitions .
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Cat. No.: HY-W009708
CAS No.: 28588-75-2
Bis (2-methyl-3-furyl) disulfide is a meat-characteristic aroma compound that binds to oral mucins. Bis (2-methyl-3-furyl) disulfide interacts with oral mucins via hydrogen bonding, hydrophobic interactions and van der Waals forces to form stable spontaneous 1:1 complexes, and the interaction strength varies with pH. Bis (2-methyl-3-furyl) disulfide contributes to the production of unique meat aroma and flavor, and its binding to oral mucins alters aroma perception .
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Cat. No.: HY-32927
CAS No.: 150255-96-2
Research Areas:  

Others

3-Cyanophenylboronic acid is an arylboronic acid-based boronic acid reagent that serves as a coupling partner in Suzuki-Miyaura cross-coupling reactions. 3-Cyanophenylboronic acid participates in reactions to synthesize 4'-propoxybiphenyl-3-carbonitrile .
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Cat. No.: HY-W127329R
CAS No.: 106-14-9
Category:  

Microorganisms

12-Hydroxystearic acid (Standard) is the analytical standard of 12-Hydroxystearic acid. This product is intended for research and analytical applications. 12-Hydroxystearic acid is a structurally simple and cost-effective low molecular weight organogelator, and its metal salts and derivatives find roles in many important applications .
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Cat. No.: HY-W009708R
CAS No.: 28588-75-2
Bis(2-methyl-3-furyl)disulfide (Standard) is the analytical standard of Bis(2-methyl-3-furyl)disulfide. This product is used for research and analytical applications. Bis(2-methyl-3-furyl)disulfide is a meat flavor characteristic aroma compound that can bind to oral mucin. Bis(2-methyl-3-furyl)disulfide can interact with oral mucin through hydrogen bonds, hydrophobic interactions, and van der Waals forces to form a stable spontaneous 1:1 complex, and the interaction intensity varies with pH. Bis(2-methyl-3-furyl)disulfide helps to produce unique meat aroma and flavor, and its binding to oral mucin will change the perception of aroma.
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Cat. No.: HY-128299
CAS No.: 324777-01-7
ALDH3A1-IN-4 is a selective ALDH3A1 inhibitor with an IC50 of 0.2 μM. ALDH3A1-IN-4 binds to the aldehyde-binding pocket of ALDH3A1 via hydrophobic interactions and van der Waals forces. ALDH3A1-IN-4 acts as a chemosensitizer that sensitizes ALDH3A1-expressing cancer cells to the antiproliferative effect of mafosfamide, but does not produce a sensitizing effect on non-cancer cells that do not express ALDH3A1. ALDH3A1-IN-4 is applicable to research related to lung adenocarcinoma and glioblastoma .
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Cat. No.: HY-N8075
CAS No.: 123549-17-7
Artonin U is an artonin. Artonin U can be isolated from Artocarpus species. Artonin U binds to hERα, as measured by docking score and Prime MM-GBSA binding free energy evaluation. Artonin U can be used in breast cancer research .
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Cat. No.: HY-125749
CAS No.: 41044-12-6
Coumarin-30 is a coumarin-based fluorescent dye and environment-sensitive fluorescent probe (in aqueous medium, λex = 430 nm, λem = 495 nm). Coumarin-30 serves as a dopant for organic light-emitting diodes .
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Cat. No.: HY-N18161
CAS No.: 3564-61-2
Isopsoralidin is a phosphatidylinositol 3-kinase (PI3K) inhibitor with potential hepatotoxicity and CYP2D6 inhibitory activity .
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