Alpi - alkaline phosphatase, intestinal Gene

Also Known as Akp6; gIAP; 2010001C14Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 76768

Summary

Predicted to enable several functions, including Alkaline Phosphatase activity; metal ion binding activity; and protein homodimerization activity. Acts upstream of or within cellular response to BMP stimulus. Predicted to be located in external side of plasma membrane. Predicted to be active in plasma membrane. Is expressed in intestine and testis. Human ortholog(s) of this gene implicated in inflammatory bowel disease. Orthologous to several human genes including ALPI (Alkaline Phosphatase, intestinal). [provided by Alliance of Genome Resources, Apr 2022]

Alpi Products (1)

mRNA Protein Name
NM_001081082.2 NP_001074551.1 intestinal alkaline phosphatase precursor

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
acts upstream of or within cellular response to BMP stimulus IDA
IDA: Inferred from direct assay
21324897 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

intestinal alkaline phosphatase

  • alkaline phosphatase 6

Recombinant Alpi Proteins

Cat. No. Product Name Accession Purity
HY-P700653 Alkaline Phosphatase/ALPI Protein, Mouse (HEK293, His) F8VPQ6/NP_001074551.1 (I21-G501) ≥ 95%, as determined by reducing SDS-PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS00628 ALPI Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS00633 ALPP Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21294 Alpi Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27813 Alpi Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Alpi NCBI NCBI:248