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Cat. No.: HY-161973

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Hydroxyl-ML-210

Hydroxyl-ML-210 is a PROTAC target protein ligand (Ligands for Target Protein for PROTACs). Hydroxyl-ML-210 can be used for synthesis ZX782 (HY-161972).

For research use only. We do not sell to patients.

Formula: C₂₂H₂₁ClN₄O₅
Molecular Weight:456.88

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (273 KB)

Hydroxyl-ML-210 Chemical Structure

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

Hydroxyl-ML-210 is a PROTAC target protein ligand (Ligands for Target Protein for PROTACs). Hydroxyl-ML-210 can be used for synthesis ZX782 (HY-161972)^[1].

Chemical Information

Molecular Weight 456.88
Formula C₂₂H₂₁ClN₄O₅
SMILES

O=C(C1=NOC(C)=C1[N+]([O-])=O)N2CCN(C(C3=CC=C(O)C=C3)C4=CC=C(Cl)C=C4)CC2
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (273 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Li X, et al. Design, Synthesis, and Biological Evaluation of Hydrophobic-Tagged Glutathione Peroxidase 4 (GPX4) Degraders. Bioorg Chem. 2024 Mar;144:107115. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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