SDZ 216-525
SDZ 216-525 is a selective silent antagonist of 5-HT1A receptor.
For research use only. We do not sell to patients.
- CAS No.: 141533-35-9
- Formula: C25H28N4O5S
- Molecular Weight:496.58
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All 5-HT Receptor Isoforms
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Biological Activity
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5-HT1A Receptor |
Chemical Information
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CAS No. 141533-35-9
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Molecular Weight 496.58
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Formula C25H28N4O5S
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SMILES
O=C(C(N1)=CC2=C1C=CC=C2N3CCN(CCCCN(C(C4=C5C=CC=C4)=O)S5(=O)=O)CC3)OC
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Boddeke H W G M, et al. Agonist/antagonist interactions with cloned human 5-HT 1A receptors: variations in intrinsic activity studied in transfected HeLa cells[J]. Naunyn-Schmiedeberg's archives of pharmacology, 1992, 345: 257-263. [Content Brief]
[2]. Sharp T, et al. The novel 5‐HT1A receptor antagonist, SDZ 216–525, decreases 5‐HT release in rat hippocampus in vivo[J]. British journal of pharmacology, 1993, 109(3): 699-702. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)