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Pelitrexol (Synonyms: AG 2037)

Cat. No.: HY-14530 Purity: 99.83%
Handling Instructions

Pelitrexol (AG 2037) is an inhibitor of glycinamide ribonucleotide formyltransferase (GARFT).

For research use only. We do not sell to patients.

Pelitrexol Chemical Structure

Pelitrexol Chemical Structure

CAS No. : 446022-33-9

Size Price Stock Quantity
5 mg USD 580 In-stock
Estimated Time of Arrival: December 31
10 mg USD 880 In-stock
Estimated Time of Arrival: December 31
50 mg USD 2500 In-stock
Estimated Time of Arrival: December 31
100 mg USD 4000 In-stock
Estimated Time of Arrival: December 31
200 mg   Get quote  
500 mg   Get quote  

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Customer Review

Based on 1 publication(s) in Google Scholar

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Description

Pelitrexol (AG 2037) is an inhibitor of glycinamide ribonucleotide formyltransferase (GARFT).

IC50 & Target

GARFT[1]

Clinical Trial
Molecular Weight

463.51

Formula

C₂₀H₂₅N₅O₆S

CAS No.

446022-33-9

SMILES

O=C(O)CC[[email protected]@H](C(O)=O)NC(C1=CC(C)=C(CC[[email protected]](CN2)CC3=C2N=C(N)NC3=O)S1)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 25 mg/mL (53.94 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.1575 mL 10.7873 mL 21.5745 mL
5 mM 0.4315 mL 2.1575 mL 4.3149 mL
10 mM 0.2157 mL 1.0787 mL 2.1575 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.08 mg/mL (4.49 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.08 mg/mL (4.49 mM); Clear solution

  • 3.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 2.08 mg/mL (4.49 mM); Clear solution

*All of the co-solvents are provided by MCE.
References
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  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

PelitrexolAG 2037AG2037AG-2037OthersInhibitorinhibitorinhibit

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Product Name:
Pelitrexol
Cat. No.:
HY-14530
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