1. Epigenetics
    Stem Cell/Wnt
    JAK/STAT Signaling
  2. JAK
  3. PF-06700841

PF-06700841 

Cat. No.: HY-112708
Handling Instructions

PF-06700841 is a dual JAK1 and TYK2 inhibitor with IC50s of 17 and 23 nM, respectively. Anti-inflammatory activity.

For research use only. We do not sell to patients.

PF-06700841 Chemical Structure

PF-06700841 Chemical Structure

CAS No. : 1883299-62-4

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Description

PF-06700841 is a dual JAK1 and TYK2 inhibitor with IC50s of 17 and 23 nM, respectively. Anti-inflammatory activity[1].

IC50 & Target

IC50: 17 nM (JAK1), 23 nM (TYK2)[1]

Clinical Trial
Molecular Weight

389.40

Formula

C₁₈H₂₁F₂N₇O

CAS No.

1883299-62-4

SMILES

O=C([[email protected]]1C(F)(F)C1)N2C3CN(C4=NC(NC5=CN(C)N=C5)=NC=C4)CC2CC3

Shipping

Room temperature in continental US; may vary elsewhere

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
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Product Name:
PF-06700841
Cat. No.:
HY-112708
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