Liposome
Liposomes (NPs typically 100–500 nm in diameter) are fabricated from the self-assembly of phospholipids, which consist of a polar phosphate head group and hydrophobic lipid tails. In aqueous environments, the hydrophobic tails self-orient, resulting in a spherical structure comprised of an aqueous core surrounded by a lipophilic bilayer membrane. Liposomes are both biocompatible and biodegradable (e.g., at certain pH and temperature), which can be controlled by modifying the lipid composition. Furthermore, liposomes are amenable to various modifications that improve their efficacy as drug delivery carriers.
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Liposome Related Products (1263)
Related Products (1263)
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C13-113-tetra-tail
0 ImagesCat. No.: HY-W440684CAS No.: 1381861-97-7C13-113-tetra tail is a cationic lipid-like compound containing a polar amino alcohol head group, four hydrophobic carbon-13 tails, and a tertiary amine linker. C13-113-tetra tail can be formulated into a lipid nanoparticle (LNP).
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DSPE-PEG3400-K237
0 ImagesCat. No.: HY-172488ADSPE-PEG3400-K237 is a PEG compound which composed of DSPE and a KDR targeting peptide (K237). K237 can functionally disrupt the interaction between VEGF and the KDR receptor and cause potent biological effects that include the inhibition of angiogenesis and tumor growth. DSPE-PEG3400-K237 can be used for drug delivery.
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Cholesterol (from plant)
0 ImagesCholesterol (from plant) is the major sterol in mammals. It is making up 20-25% of structural component of the plasma membrane. Plasma membranes are highly permeable to water but relatively impermeable to ions and protons. Cholesterol (from plant) plays an important role in determining the fluidity and permeability characteristics of the membrane as well as the function of both the transporters and signaling proteins. Cholesterol (from plant) is also an endogenous estrogen-related receptor α (ERRα) agonist.
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DSPE-PEG5000-YIGSR
0 ImagesCat. No.: HY-172477DSPE-PEG5000-YIGSR is a PEG compound which composed of DSPE and a biomimetic peptide YIGSR. YIGSR interacts with the 67 kDa laminin binding protein (LBP) and promotes adhesion and spreading of a large number of cell types including endothelial cells, fibroblasts and smooth muscle cells. DSPE-PEG5000-YIGSR can be used for drug delivery.
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DMG-PEG1000-Alkyne
0 ImagesCat. No.: HY-183191DMG-PEG1000-Alkyne is a conjugate composed of dimyristic glycerol (DMG), a PEG chain, and a terminal alkyne group. DMG-PEG1000-Alkyne combines the membrane compatibility of phospholipids with the high reactivity of the alkyne group in click chemistry, making it suitable for research in biomaterial construction and drug delivery.
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19:0 PC
0 ImagesSynonyms: 1,2-DNPC; 1,2-Dinonadecanoyl-sn-glycero-3-phosphocholine19:0 PC is a saturated phospholipid that has been used as a standard for the quantification of phosphatidylcholines in human synovial fluid. It has also been used to study dynamics of lipid bilayer phase transition.
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Phospholipid-PEG2000-Biotin
0 ImagesCat. No.: HY-147207APhospholipid-PEG2000-Biotin is a Biotin labeled phospholipid PEG derivative, can be used for modify liposome and cells surface, and pancreatic islets for cell transplantation. Phospholipid is a class of lipid containing a hydrophilic "head" and two hydrophobic "tails" ; PEG is a hydrophilic and water-soluble polymer with low toxicity; Biotin is an enzyme co-factor, can be used for labeling protein.
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Ionizable Lipid 4
0 ImagesCat. No.: HY-159861CAS No.: 1799316-81-6Ionizable Lipid 4 is an ionizable cationic lipid and a rearrangement product of the cationic lipid CA-lipid 5 induced by hydrogen peroxide.
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DSPE-succinic acid (Standard)
0 ImagesCat. No.: HY-W441002RCAS No.: 248253-94-3Taurine (Standard) is the analytical standard of Taurine. This product is intended for research and analytical applications. Taurine, a sulphur-containing amino acid and an organic osmolyte involved in cell volume regulation, provides a substrate for the formation of bile salts, and plays a role in the modulation of intracellular free calcium concentration. Taurine has the ability to activate autophagy in adipocytes.
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18:1 Glutaryl PE monosodium
0 ImagesCat. No.: HY-150240ACAS No.: 111516-02-0Synonyms: DOPE-GA monosodium18:1 Glutaryl PE monosodium is a functionalized lipid.
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DSPE-PEG3000-iRGD
0 ImagesCat. No.: HY-172495DSPE-PEG3000-iRGD is a PEG compound which composed of DSPE and an αv-integrins targeting peptide (iRGD). iRGD peptide binds to αv-integrins, and then proteolytically cleaved in the tumor to produce CRGDK/R to interact with neuropilin-1, and has tumor-targeting and tumor-penetrating properties. DSPE-PEG3000-iRGD can be used for drug delivery.
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(R)-DOTMA
0 ImagesCat. No.: HY-139200ACAS No.: 2101981-60-4(R)-DOTMA is a cationic lipid that can be used to construct lipid nanoparticles and lipoplexes. (R)-DOTMA binds nucleic acid molecules such as mRNA through electrostatic interactions, facilitating nucleic acid encapsulation and cellular delivery. (R)-DOTMA can form lipid systems with DOPE (HY-112005) or cholesterol (HY-N0322). (R)-DOTMA is applicable to mRNA delivery, vaccine development, cancer immunotherapy and gene editing research.
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DPPE-PEG550
0 ImagesCat. No.: HY-144012BCAS No.: 474922-84-4Synonyms: 16:0 PEG550 PE; 1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-550] ammoniumDPPE-PEG550 is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymer nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
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DOPE-PEG10000-NHS
0 ImagesCat. No.: HY-203300DDOPE-PEG1000-NHS is a conjugate composed of DOPE, PEG chains, and terminal active ester (NHS). The NHS ester in DOPE-PEG1000-NHS can rapidly covalently react with molecules containing primary amines (such as proteins, peptide chains, and small molecules modified with amino groups) to form stable amide bonds, suitable for the construction of carriers requiring membrane fusion properties or pH-sensitive release (such as gene delivery systems).
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DSG-PEG2000-Alkyne
0 ImagesCat. No.: HY-183172ADSG-PEG2000-Alkyne is a conjugate composed of DSG, a PEG chain, and a terminal alkyne group. DSG-PEG2000-Alkyne combines the membrane compatibility of phospholipids with the high reactivity of the alkyne group in click chemistry, making it suitable for research in biomaterial construction and drug delivery.
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DSPE-PEG3400-GE11
0 ImagesCat. No.: HY-172470A
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DSPE-PEG5000-CRPPR
0 ImagesCat. No.: HY-177205CDSPE-PEG5000-CRPPR is a PEG compound which composed of DSPE and a?Heart-homing peptide?(CRPPR) (HY-P10641). CRPPR is a linear peptide containing arginine that has the ability to specifically bind to the cardiac endothelium and uses cysteine-rich protein-2 (CRIP-2) as its receptor. DSPE-PEG5000-CGKRK can be used for drug delivery.
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mPEG30000-DMG
0 ImagesCat. No.: HY-112764ECAS No.: 160743-62-4mPEG30000-DMG is a PEGylated phospholipid containing DMG. mPEG30000-DMG combines the membrane fusion capability of DMG with the stealth properties of PEG, and can be used for applications such as constructing targeted drug delivery systems and liposome preparation.
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DOPE-PEG2000-Azide
0 ImagesCat. No.: HY-W591449DOPE-PEG2000-Azide is a liposome to simulate biological phospholipid membrane. Liposomes are the main component of vesicles with concentric phospholipid bilayer membranes, which can be used to construct drug delivery systems for anti-cancer and anti-infection fields. Highly polar water-soluble payloads can be trapped in the internal aqueous space of liposomes, while lipophilic payloads can partition into and become part of the lipid bilayer. Especially for delivering antisense oligonucleotides, it can overcome problems such as inefficient cellular uptake and rapid loss in the body.
