PNPLA3
Patatin-like phospholipase domain-containing protein 3; Adiponutrin; iPLA2-epsilon; Calcium-independent phospholipase A2-epsilon; Acylglycerol O-acyltransferase
Patatin-like phospholipase domain-containing protein 3 (PNPLA3) is a triacylglycerol lipase that mediates triacylglycerol hydrolysis in adipocytes. It is involved in the triacylglycerol hydrolysis in adipocytes and may play a role in energy metabolism.
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PNPLA3 Related Products (11)
Related Products (11)
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PF-07853578
0 ImagesPF-07853578 is an orally active PNPLA3 modulator. PF-07853578 significantly reduces human PNPLA3-I148M protein levels and effectively decreases hepatic triglyceride content by reducing this mutant protein. PNPLA3 degrader-1 can be used in the research of liver cirrhosis and hepatocellular carcinoma.
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Dihydrocurcumin
0 ImagesDihydrocurcumin, a major metabolites of curcumin, reduces lipid accumulation and oxidative stress. Dihydrocurcumin regulates mRNA and protein expression levels of SREBP-1C, PNPLA3 and PPARα, increases protein expression levels of pAKT and PI3K, and reduced the levels of cellular NO and ROS via Nrf2 signaling pathways.
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PNPLA3 Human Pre-designed siRNA Set A
0 ImagesCat. No.: HY-RS10794PNPLA3 Human Pre-designed siRNA Set A contains three designed siRNAs for PNPLA3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
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Edutirsen
0 ImagesEdutirsen, an antisense oligonucleotide, is a 1-acylglycerol-3-phosphate O-acyltransferase (PNPLA3) synthesis reducer.
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Pivicasiran sodium
0 ImagesCat. No.: HY-177656APivicasiran sodium, a siRNA, is a adiponutrin synthesis reducer.
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Pivicasiran sodium scrambled negative control
0 ImagesCat. No.: HY-177656BPivicasiran sodium scrambled negative control is the sequence scrambled negative control of Pivicasiran sodium.
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Elsunersen sodium scrambled negative control
0 ImagesCat. No.: HY-177629BElsunersen sodium scrambled negative control is the sequence scrambled negative control of Elsunersen sodium.
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Edutirsen sodium
0 ImagesCat. No.: HY-177628AEdutirsen sodium, an antisense oligonucleotide, is a 1-acylglycerol-3-phosphate O-acyltransferase (PNPLA3) synthesis reducer.
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Pivicasiran
0 ImagesCat. No.: HY-177656CAS No.: 2654847-29-5Pivicasiran, a siRNA, is a adiponutrin synthesis reducer.
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PNPLA3 modifier 1
0 ImagesCat. No.: HY-159656CAS No.: 3036158-95-6PNPLA3 modifier 1 (compound 10) is a Patatin-like phospholipase domain-containing protein 3 (pnpla3) modifier, with a geometric mean EC50 of 4.9 nM.
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