3036158-98-9
3036158-98-9
Chemical Structure
PF-07853578
- CAS No.: 3036158-98-9
- Formula:C16H19ClF2N2O4S
- Molecular Weight:408.85
InChIKey: LWZQGRRGKYWBQG-DGCLKSJQSA-N
SMILES: O=S1(N(CC[C@H]1C)[C@H]2CN(CC(F)(C2)F)C(OC3=CC=C(C=C3)Cl)=O)=O
Biological Activity: PF-07853578 is an orally active PNPLA3 modulator. PF-07853578 significantly reduces human PNPLA3-I148M protein levels and effectively decreases hepatic triglyceride content by reducing this mutant protein. PNPLA3 degrader-1 can be used in the research of liver cirrhosis and hepatocellular carcinoma[1][2].
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PF-07853578 | 99.08% | PF-07853578 is an orally active PNPLA3 modulator. PF-07853578 significantly reduces human PNPLA3-I148M protein levels and effectively decreases hepatic triglyceride content by reducing this mutant protein. PNPLA3 degrader-1 can be used in the research of liver cirrhosis and hepatocellular carcinoma. | ||||||||||||||||||||
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