Drug Intermediate
Drug Iintermediate
Drug intermediates are used as raw materials for the production of bulk drugs, or they can refer to a material produced during synthesis of an API that must undergo further molecular change or processing before it becomes an API. Drug intermediates are hygienically formulated using high grade raw materials and they are used in the pharmaceutical and cosmetic industry[1][2].
References:
- [1]. Ma HC, et al. Homochiral Covalent Organic Framework for Catalytic Asymmetric Synthesis of a Drug Intermediate. J Am Chem Soc. 2020 Jul 22;142(29):12574-12578. [Content Brief]
- [2]. Ramachary D B, et al. Development of pharmaceutical drugs, drug intermediates and ingredients by using direct organo‐click reactions[J]. 2008.
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Drug Intermediate Related Products (4595)
Related Products (4595)
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4-Iodoaniline, 98%
0 Images4-Iodoaniline is a potent methemoglobin former. 4-Iodoaniline is also an intermediate. 4-Iodoaniline can be used to synthesize glycogen phosphorylase inhibitors. 4-Iodoaniline is used in the research of liver cancer and blood diseases.
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3-Oxopentanedioic acid
0 Images3-Oxopentanedioic acid is a dicarboxylic acid that is easily brominated. 3-Oxopentanedioic acid can be used as an intermediate in organic chemical synthesis.
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3-Aminopentane
0 Images3-Aminopentane is a monoalkylamine compound containing a primary aliphatic amine group. 3-Aminopentane is a building block in the chemical synthesis.
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2,3,4,5-Tetrahydro-3-(trifluoroacetyl)-1,5-methano-1H-3-benzazepine-7,8-diamine
0 Images2,3,4,5-Tetrahydro-3-(trifluoroacetyl)-1,5-methano-1H-3-benzazepine-7,8-diamine is a drug intermediate for synthesis of various active compounds.
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(S)-1-(3-Ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethanamine
0 Images(S)-1-(3-Ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethanamine is a drug intermediate for synthesis of various active compounds.
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3,4,5-Trimethoxybenzaldehyde
0 Images3,4,5-Trimethoxybenzaldehyde is a derivative of benzaldehyde. 3,4,5-Trimethoxybenzaldehyde has antimicrobial activity. 3,4,5-Trimethoxybenzaldehyde is also an important intermediate for the synthesis of various drugs, such as Trimethoprim (HY-B0510).
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N-Acetylneuraminic Acid Methyl Ester 2,4,7,8,9-Pentaacetate
0 ImagesCat. No.: HY-I0402CAS No.: 73208-82-9N-Acetylneuraminic Acid Methyl Ester 2,4,7,8,9-Pentaacetate is a drug intermediate for synthesis of various active compounds.
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rel-(2R,3S)-1,2,3,4-Tetrahydro-1,4-methanonaphthalene-2,3-diol
0 Imagesrel-(2R,3S)-1,2,3,4-Tetrahydro-1,4-methanonaphthalene-2,3-diol is a drug intermediate for synthesis of various active compounds.
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Thiazolidine hydrochloride
0 ImagesThiazolidine hydrochloride is a drug intermediate for synthesis of various active compounds.
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2-(2-(2-Chloroethoxy)ethoxy)ethanol
0 ImagesSynonyms: Triethylene glycol monochlorohydrin2-(2-(2-Chloroethoxy)ethoxy)ethanol (Triethylene glycol monochlorohydrin) is a low-molecular-weight polyethylene glycol chloride compound and can be used as a drug intermediate.
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4-(4-Aminophenyl)morpholin-3-one
0 Images4-(4-Aminophenyl)morpholin-3-one is a drug intermediate for synthesis of various active compounds.
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N-Isovaleroylglycine
0 ImagesN-Isovaleroylglycine is a peptidylglycine α-amidating monooxygenase (PAM) inhibitor with a Ki value of 2.0 mM against human hsPAM. N-Isovaleroylglycine undergoes oxidative cleavage by purified rat PAM to produce fatty acid amide and glyoxylic acid. N-Isovaleroylglycine exerts competitive inhibition by binding to hsPAM, blocking the amidation of dansyl-Tyr-Val-Gly. N-Isovaleroylglycine exhibits lowered urinary abundance in MRSA-infected mice, which qualifies it as a non-invasive biomarker. N-Isovaleroylglycine can be used in studies related to Staphylococcus aureus pneumonia and diabetic foot.
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4'-Fluoroacetophenone
0 Images4'-Fluoroacetophenone (1-(4-Fluorophenyl)ethan-1-one) is p-fluoroacetophenone, and serves as a substrate for both SNAr dimerization reactions and cross SNAr reactions. 4'-Fluoroacetophenone is also an important intermediate that can be used in the synthesis of other active compounds, such as aromatic diketones.
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DavePhos
0 ImagesDavePhos is a phosphine ligand and electron donor. DavePhos can form cationic rhodium complexes to promote the selective hydrocarboxylation of styrene derivatives with CO2 and H2. As a sacrificial electron donor, DavePhos assists in generating active Rh-H species to initiate the catalytic cycle. DavePhos can be used in Buchwald−Hartwig cross-coupling reactions within palladium-based catalytic systems. DavePhos is applicable to platinum-catalyzed reductive amination of amine-acid.
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(S)-BINAP
0 Images(S)-BINAP is an isomer of (R)-BINAP (HY-W017757), as well as a chiral chelating diphosphine ligand and enantioselective catalyst precursor. (S)-BINAP acts as a bidentate ligand, transferring chiral information via its binaphthyl backbone to achieve stereodiscrimination of substrates. (S)-BINAP is used for the enantioselective hydrogenation of prochiral carboxylic acids, N-acyltetrahydroisoquinolines, allylic alcohols, functionalized ketones, cyclic anhydrides, and styrenes.
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4-Amino-L-phenylalanine
0 Images4-Amino-L-phenylalanine is a metabolic intermediate. 4-Amino-L-phenylalanine can be used in the production of Chloramphenicol (HY-B0239) and Pristinamycin I in Streptomyces venezuelae and S. pristinaespiralis, respectively.
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Ethylboronic acid
0 ImagesEthylboronic acid is an organic boron compound that can be used as a synthetic intermediate.
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5-Bromo-2,3-dihydro-1H-inden-1-one
0 Images5-Bromo-2,3-dihydro-1H-inden-1-one is an important indanone intermediate that is widely used in the synthesis of anti-tumor indanone derivatives.
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Cyjohnphos
0 ImagesSynonyms: 2-(Dicyclohexylphosphino)biphenylCyJohnPhos (2-(Dicyclohexylphosphino)biphenyl) is an organophosphine ligand. Gold (I) complexes derived from CyJohnPhos exhibit anti-colon cancer activity, inhibit the enzymatic activities of COX-1/COX-2 and TrxR, upregulate ROS levels, induce cell apoptosis, and some derivatives can induce cell cycle arrest. CyJohnPhos can serve as an intermediate for research related to organic synthesis.
