DavePhos
Based on 1 Customer Validation
DavePhos is a phosphine ligand and electron donor. DavePhos can form cationic rhodium complexes to promote the selective hydrocarboxylation of styrene derivatives with CO2 and H2. As a sacrificial electron donor, DavePhos assists in generating active Rh-H species to initiate the catalytic cycle. DavePhos can be used in Buchwald−Hartwig cross-coupling reactions within palladium-based catalytic systems. DavePhos is applicable to platinum-catalyzed reductive amination of amine-acid.
For research use only. We do not sell to patients.
- Purity: 98.0%
- CAS No.: 213697-53-1
- Formula: C26H36NP
- Molecular Weight:393.54
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Storage:
4°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
DavePhos can act as both a ligand and an electron donor to enable the hydrocarboxylation of methyl 4-vinylbenzoate under ambient temperature and atmospheric CO2/H2 pressure, producing the branched carboxylic acid product 2a[2].
DavePhos combined with Karstedt catalyst enables efficient homogeneous platinum‑catalyzed reductive amination between leelamine and carboxylic acids to prepare lysosome‑targeted analogs; this catalytic system also supports nanoscale synthesis of a leelamine analog library containing 1280 members[3].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 213697-53-1
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Appearance Solid
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Molecular Weight 393.54
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Formula C26H36NP
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Color Off-white to light yellow
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SMILES
CN(C)C(C=CC=C1)=C1C2=C(P(C3CCCCC3)C4CCCCC4)C=CC=C2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
Solvent & Solubility
DMF : 6.67 mg/mL (16.95 mM; ultrasonic and warming and heat to 60°C)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (275 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMF | 1 mM | 2.5410 mL | 12.7052 mL | 25.4104 mL | 63.5259 mL |
| 5 mM | 0.5082 mL | 2.5410 mL | 5.0821 mL | 12.7052 mL | |
| 10 mM | 0.2541 mL | 1.2705 mL | 2.5410 mL | 6.3526 mL | |
| 15 mM | 0.1694 mL | 0.8470 mL | 1.6940 mL | 4.2351 mL |
DavePhos Related Classifications
HY-W002925 Related Classifications
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