943-80-6
Chemical Structure
4-Amino-L-phenylalanine
Synonym(s): H-Phe(4-NH2)-OH
- CAS No.: 943-80-6
- Formula:C9H12N2O2
- Molecular Weight:180.21
IUPAC Name: (S)-2-amino-3-(4-aminophenyl)propanoic acid
InChIKey: CMUHFUGDYMFHEI-QMMMGPOBSA-N
SMILES: N[C@@H](CC1=CC=C(N)C=C1)C(O)=O
Biological Activity: 4-Amino-L-phenylalanine (H-Phe(4-NH2)-OH) is a metabolic intermediate and an α-carbonic anhydrase (TcCA) activator with a Ka value of 0.75 μM. 4-Amino-L-phenylalanine acts through active site cavity entrance binding and a proton shuttle mechanism to enhance the catalytic rate of CO2 hydration. 4-Amino-L-phenylalanine serves as a diamine monomer for bio-based polymer synthesis and is produced in Escherichia coli via the shikimate pathway. 4-Amino-L-phenylalanine constitutes a structural component of haptens used in immunoassay development. 4-Amino-L-phenylalanine is used for the production of Chloramphenicol (HY-B0239) and Pristinamycin I in Streptomyces venezuelae and S. pristinaespiralis, respectively. 4-Amino-L-phenylalanine is used in research related to Trypanosoma cruzi infection[1][2][3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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4-Amino-L-phenylalanine | 99.98% | 4-Amino-L-phenylalanine (H-Phe(4-NH2)-OH) is a metabolic intermediate and an α-carbonic anhydrase (TcCA) activator with a Ka value of 0.75 μM. 4-Amino-L-phenylalanine acts through active site cavity entrance binding and a proton shuttle mechanism to enhance the catalytic rate of CO2 hydration. 4-Amino-L-phenylalanine serves as a diamine monomer for bio-based polymer synthesis and is produced in Escherichia coli via the shikimate pathway. 4-Amino-L-phenylalanine constitutes a structural component of haptens used in immunoassay development. 4-Amino-L-phenylalanine is used for the production of Chloramphenicol (HY-B0239) and Pristinamycin I in Streptomyces venezuelae and S. pristinaespiralis, respectively. 4-Amino-L-phenylalanine is used in research related to Trypanosoma cruzi infection. | ||||||||||||||||||||
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4-Amino-L-phenylalanine (Standard) | ≥98% | 4-Amino-L-phenylalanine (Standard) (H-Phe(4-NH2)-OH (Standard)) is the analytical standard of 4-Amino-L-phenylalanine (HY-W016480). This product is intended for research and analytical applications. 4-Amino-L-phenylalanine (H-Phe(4-NH2)-OH) is a metabolic intermediate and an α-carbonic anhydrase (TcCA) activator with a Ka value of 0.75 μM. 4-Amino-L-phenylalanine acts through active site cavity entrance binding and a proton shuttle mechanism to enhance the catalytic rate of CO2 hydration. 4-Amino-L-phenylalanine serves as a diamine monomer for bio-based polymer synthesis and is produced in Escherichia coli via the shikimate pathway. 4-Amino-L-phenylalanine constitutes a structural component of haptens used in immunoassay development. 4-Amino-L-phenylalanine is used for the production of Chloramphenicol (HY-B0239) and Pristinamycin I in Streptomyces venezuelae and S. pristinaespiralis, respectively. 4-Amino-L-phenylalanine is used in research related to Trypanosoma cruzi infection. | ||||||||||||||||||||
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References
- [1]. Kawaguchi H, et al. Metabolic engineering for 4-aminophenylalanine production from lignocellulosic biomass by recombinant Escherichia coli. RSC Sustainability, 2023, 1(4): 1043-1054.
- [2]. Angeli A, et al. Activation studies with amines and amino acids of the α-carbonic anhydrase from the pathogenic protozoan Trypanosoma cruzi. Bioorganic & medicinal chemistry. 2018 Aug 07;26(14):4187-4190.
- [3]. Shan G, et al. An enzyme-linked immunosorbent assay for the detection of esfenvalerate metabolites in human urine. Chemical research in toxicology. 1999 Nov;12(11):1033-41.
