N-Acetylneuraminic Acid Methyl Ester 2,4,7,8,9-Pentaacetate

Cat. No.: HY-I0402 Purity: 95.0%: Data Sheet
COA

SDS
Handling Instructions
FAQs
Technical Support

N-Acetylneuraminic Acid Methyl Ester 2,4,7,8,9-Pentaacetate is a drug intermediate for synthesis of various active compounds.

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N-Acetylneuraminic Acid Methyl Ester 2,4,7,8,9-Pentaacetate 화학구조

CAS No. : 73208-82-9

사이즈	재고	수량
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO ready for reconstitution	해외재고보유	Estimated Time of Arrival: December 31
Solution
10 mM * 1 mL in DMSO	해외재고보유	Estimated Time of Arrival: December 31
Solid
250 mg	해외재고보유	Estimated Time of Arrival: December 31
500 mg	해외재고보유	Estimated Time of Arrival: December 31
1 g	해외재고보유	Estimated Time of Arrival: December 31
5 g	해외재고보유	Estimated Time of Arrival: December 31
10 g	해외재고보유	Estimated Time of Arrival: December 31
50 g	견적 받기

or 대량구매 문의

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

This product is a controlled substance and not for sale in your territory.

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Biological Activity
순도&문서
고객리뷰

제품 설명

N-Acetylneuraminic Acid Methyl Ester 2,4,7,8,9-Pentaacetate is a drug intermediate for synthesis of various active compounds.

분자량

533.48

화학식

C₂₂H₃₁NO₁₄

CAS No.

73208-82-9

Appearance

Solid

Color

White to off-white

SMILES

O=C(C(O[C@@]1([H])[C@H](OC(C)=O)[C@H](OC(C)=O)COC(C)=O)(C[C@H](OC(C)=O)[C@H]1NC(C)=O)OC(C)=O)OC

선적

Room temperature in continental US; may vary elsewhere.

보관

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

용액&용해도

In Vitro:

DMSO : 200 mg/mL (374.90 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	1.8745 mL	9.3724 mL	18.7448 mL
5 mM	0.3749 mL	1.8745 mL	3.7490 mL
10 mM	0.1874 mL	0.9372 mL	1.8745 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

몰농도 계산기
농도 희석 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo:

Select the appropriate dissolution method based on your experimental animal and administration route.

For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for in vivo experiments, it is recommended to prepare freshly and use it on the same day.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

Protocol 1

Add each solvent one by one: 10% DMSO 40% PEG300 5% Tween-80 45% Saline
Solubility: ≥ 5 mg/mL (9.37 mM); Clear solution

This protocol yields a clear solution of ≥ 5 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (50.0 mg/mL) to 400 μL PEG300, and mix evenly; then add 50 μL Tween-80 and mix evenly; then add 450 μL Saline to adjust the volume to 1 mL.
Preparation of Saline: Dissolve 0.9 g sodium chloride in ddH₂O and dilute to 100 mL to obtain a clear Saline solution.
Protocol 2

Add each solvent one by one: 10% DMSO 90% (20% SBE-β-CD in Saline)
Solubility: ≥ 5 mg/mL (9.37 mM); Clear solution

This protocol yields a clear solution of ≥ 5 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (50.0 mg/mL) to 900 μL 20% SBE-β-CD in Saline, and mix evenly.
Preparation of 20% SBE-β-CD in Saline (4°C, storage for one week): 2 g SBE-β-CD powder is dissolved in 10 mL Saline, completely dissolve until clear.
Protocol 3

Add each solvent one by one: 10% DMSO 90% Corn Oil
Solubility: 5 mg/mL (9.37 mM); Suspended solution; Need ultrasonic

This protocol yields a suspended solution of 5 mg/mL. Suspended solution can be used for oral and intraperitoneal injection.
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (50.0 mg/mL) to 900 μL Corn oil, and mix evenly.

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Please enter your animal formula composition:

DMSO +

Tween-80 +

Saline

Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.

The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).

Calculation results:

Working solution concentration: mg/mL

Method for preparing stock solution: mg drug dissolved in μL DMSO (Stock solution concentration: mg/mL).

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only. If necessary, please contact MedChemExpress (MCE).

Method for preparing in vivo working solution for animal experiments: Take μL DMSO stock solution, add μL . μL , mix evenly, next add μL Tween 80, mix evenly, then add μL Saline.

If the continuous dosing period exceeds half a month, please choose this protocol carefully.

Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.

순도&문서

Purity: 95.0%

Select Batch:

Data Sheet (252 KB) SDS (393 KB)

COA (258 KB) HNMR (305 KB)

Handling Instructions (2659 KB)

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	1.8745 mL	9.3724 mL	18.7448 mL	46.8621 mL
	5 mM	0.3749 mL	1.8745 mL	3.7490 mL	9.3724 mL
	10 mM	0.1874 mL	0.9372 mL	1.8745 mL	4.6862 mL
	15 mM	0.1250 mL	0.6248 mL	1.2497 mL	3.1241 mL
	20 mM	0.0937 mL	0.4686 mL	0.9372 mL	2.3431 mL
	25 mM	0.0750 mL	0.3749 mL	0.7498 mL	1.8745 mL
	30 mM	0.0625 mL	0.3124 mL	0.6248 mL	1.5621 mL
	40 mM	0.0469 mL	0.2343 mL	0.4686 mL	1.1716 mL
	50 mM	0.0375 mL	0.1874 mL	0.3749 mL	0.9372 mL
	60 mM	0.0312 mL	0.1562 mL	0.3124 mL	0.7810 mL
	80 mM	0.0234 mL	0.1172 mL	0.2343 mL	0.5858 mL
	100 mM	0.0187 mL	0.0937 mL	0.1874 mL	0.4686 mL