1. Metabolic Enzyme/Protease
    PI3K/Akt/mTOR
    Autophagy
  2. Mitochondrial Metabolism
    PTEN
    Autophagy
  3. Afzelin

Afzelin (Synonyms: Kaempferol-3-O-rhamnoside)

Cat. No.: HY-N1441
Handling Instructions

Afzelin (Kaempferol-3-O-rhamnoside) is is a flavonol glycoside found in Houttuynia cordata Thunberg and is widely used in the preparation of antibacterial and antipyretic agents, detoxicants and for the treatment of inflammation. Afzelin attenuates the mitochondrial damage, enhances mitochondrial biogenesis and decreases the level of mitophagy-related proteins, parkin and PTEN-induced putative kinase 1. Afzelin improves the survival rate and reduces the serum levels of alanine aminotransferase and pro-inflammatory cytokines in D-galactosamine (GalN)/LPS -treated mice.

For research use only. We do not sell to patients.

Afzelin Chemical Structure

Afzelin Chemical Structure

CAS No. : 482-39-3

Size Price Stock Quantity
10 mM * 1 mL in DMSO USD 148 In-stock
Estimated Time of Arrival: December 31
1 mg USD 52 In-stock
Estimated Time of Arrival: December 31
5 mg USD 156 In-stock
Estimated Time of Arrival: December 31
10 mg USD 265 In-stock
Estimated Time of Arrival: December 31
25 mg USD 530 In-stock
Estimated Time of Arrival: December 31
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Description

Afzelin (Kaempferol-3-O-rhamnoside) is is a flavonol glycoside found in Houttuynia cordata Thunberg and is widely used in the preparation of antibacterial and antipyretic agents, detoxicants and for the treatment of inflammation. Afzelin attenuates the mitochondrial damage, enhances mitochondrial biogenesis and decreases the level of mitophagy-related proteins, parkin and PTEN-induced putative kinase 1. Afzelin improves the survival rate and reduces the serum levels of alanine aminotransferase and pro-inflammatory cytokines in D-galactosamine (GalN)/LPS -treated mice[1].

Molecular Weight

432.38

Formula

C₂₁H₂₀O₁₀

CAS No.

482-39-3

SMILES

O=C1C(O[[email protected]]2[[email protected]@H]([[email protected]@H]([[email protected]]([[email protected]](C)O2)O)O)O)=C(C3=CC=C(O)C=C3)OC4=CC(O)=CC(O)=C14

Shipping

Room temperature in continental US; may vary elsewhere

Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

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Afzelin
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