PSMG2 Antibody (YA8181)
(Synonyms: CLAST3; HCCA3; HsT1707; MDS003; PAC2; TNFSF5IP1)PSMG2 Antibody (YA8181) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to PSMG2.
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Host:
Mouse
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Isotype:
IgG2b
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Application:
ICC/IF
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Reactivity :
Human, Mouse, Rat
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Formulation:
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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Conjugation:
Non-conjugated
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Applications
| Application |
ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
|---|---|
| Dilution Ratio | 1:100-250 |
Product Details
PSMG2 Antibody (YA8181) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to PSMG2.
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Host Mouse
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Clonality Monoclonal
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Species ReactivityHuman, Mouse, Rat
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Calculated Molecular Weight Predicted band size: 29.2 kDa
Full length human recombinant protein of human PSMG2 produced in E.coli.
Endogenous
Affinity purified
Non-conjugated
Unmodified
IgG2b
Product Properties
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Appearance
Liquid
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Formulation
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
PSMG2 is a Chaperone protein which promotes assembly of the 20S proteasome as part of a heterodimer with PSMG1. The PSMG1-PSMG2 heterodimer binds to the PSMA5 and PSMA7 proteasome subunits, promotes assembly of the proteasome alpha subunits into the heteroheptameric alpha ring and prevents alpha ring dimerization
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Subcellular Localization
Nucleus
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Expression
Tissue_Specificity: Widely expressed with highest levels in lung, brain and colon. Moderately expressed in muscle, stomach, spleen and heart. Weakly expressed in small intestine, pancreas and liver. Highly expressed in hepatocellular carcinomas with low levels in surrounding liver tissue -
Isoforms & Post-Translational Modification
Q969U7 has two isomers: Q969U7-1: 29396 Da (predicted); Q969U7-2: 26321 Da (predicted).
Degraded by the proteasome upon completion of 20S proteasome maturation -
Subunit
Forms a heterodimer with PSMG1
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SwissProt ID
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Synonyms
CLAST3; HCCA3; HsT1707; MDS003; PAC2; TNFSF5IP1
Documentation
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