Averythrin
Averythrin is an antibacterial agent that can be used in studies related to Staphylococcus aureus infections.
For research use only. We do not sell to patients.
- CAS No.: 25340-85-6
- Formula: C20H18O6
- Molecular Weight:354.36
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| H9c2 | IC50 |
62.1 μM
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Cytotoxicity against normal rat H9c2 cardiomyocytes assessed as reduction in cell viability after 24 h incubation by MTT assay.
Cytotoxicity against normal rat H9c2 cardiomyocytes assessed as reduction in cell viability after 24 h incubation by MTT assay.
|
41123691 |
| HaCaT | IC50 |
56.5 μM
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Cytotoxicity against normal human HaCaT keratinocytes assessed as reduction in cell viability after 24 h incubation by MTT assay.
Cytotoxicity against normal human HaCaT keratinocytes assessed as reduction in cell viability after 24 h incubation by MTT assay.
|
41123691 |
| H9c2 | IC50 |
61.5 μM
|
Cytotoxicity against normal rat H9c2 cardiomyocytes assessed as reduction in cell viability after 48 h incubation by MTT assay.
Cytotoxicity against normal rat H9c2 cardiomyocytes assessed as reduction in cell viability after 48 h incubation by MTT assay.
|
41123691 |
| HaCaT | IC50 |
57.1 μM
|
Cytotoxicity against normal human HaCaT keratinocytes assessed as reduction in cell viability after 48 h incubation by MTT assay.
Cytotoxicity against normal human HaCaT keratinocytes assessed as reduction in cell viability after 48 h incubation by MTT assay.
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41123691 |
Averythrin (compound 7) (1.563-100 μM; 18 h) potently inhibits Staphylococcus aureus growth and biofilm formation with IC50 values of 11.36 μM and 10.66 μM, respectively[2].
Averythrin (up to 100 μM; 24-48 h) exhibits moderate, time-stable cytotoxicity to normal H9c2 cardiomyocytes and HaCaT keratinocytes, with IC50 values ranging from 56.5 μM to 62.1 μM across 24 h and 48 h incubations[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:normal rat H9c2 cardiomyocytes, normal human HaCaT keratinocytes
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Concentration:up to 100 μM
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Incubation Time:24 h, 48 h
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Result:Exhibited moderate cytotoxicity to H9c2 cells with an IC50 of 62.1 μM after 24 h incubation.
Exhibited moderate cytotoxicity to HaCaT cells with an IC50 of 56.5 μM after 24 h incubation.
Exhibited moderate cytotoxicity to H9c2 cells with an IC50 of 61.5 μM after 48 h incubation.
Exhibited moderate cytotoxicity to HaCaT cells with an IC50 of 57.1 μM after 48 h incubation.
Chemical Information
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CAS No. 25340-85-6
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Molecular Weight 354.36
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Formula C20H18O6
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SMILES
O=C1C=2C(C(=O)C=3C1=C(O)C=C(O)C3)=CC(O)=C(/C=C/CCCC)C2O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Averythrin Related Classifications
HY-187651 Related Classifications
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