Averythrin
Averythrin is an antibacterial agent that can be used in studies related to Staphylococcus aureus infections.
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- CAS No.: 25340-85-6
- Formule: C20H18O6
- Masse moléculaire:354.36
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Activité biologique
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| H9c2 | IC50 |
62.1 μM
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Cytotoxicity against normal rat H9c2 cardiomyocytes assessed as reduction in cell viability after 24 h incubation by MTT assay.
Cytotoxicity against normal rat H9c2 cardiomyocytes assessed as reduction in cell viability after 24 h incubation by MTT assay.
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41123691 |
| HaCaT | IC50 |
56.5 μM
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Cytotoxicity against normal human HaCaT keratinocytes assessed as reduction in cell viability after 24 h incubation by MTT assay.
Cytotoxicity against normal human HaCaT keratinocytes assessed as reduction in cell viability after 24 h incubation by MTT assay.
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41123691 |
| H9c2 | IC50 |
61.5 μM
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Cytotoxicity against normal rat H9c2 cardiomyocytes assessed as reduction in cell viability after 48 h incubation by MTT assay.
Cytotoxicity against normal rat H9c2 cardiomyocytes assessed as reduction in cell viability after 48 h incubation by MTT assay.
|
41123691 |
| HaCaT | IC50 |
57.1 μM
|
Cytotoxicity against normal human HaCaT keratinocytes assessed as reduction in cell viability after 48 h incubation by MTT assay.
Cytotoxicity against normal human HaCaT keratinocytes assessed as reduction in cell viability after 48 h incubation by MTT assay.
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41123691 |
Averythrin (compound 7) (1.563-100 μM; 18 h) potently inhibits Staphylococcus aureus growth and biofilm formation with IC50 values of 11.36 μM and 10.66 μM, respectively[2].
Averythrin (up to 100 μM; 24-48 h) exhibits moderate, time-stable cytotoxicity to normal H9c2 cardiomyocytes and HaCaT keratinocytes, with IC50 values ranging from 56.5 μM to 62.1 μM across 24 h and 48 h incubations[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:normal rat H9c2 cardiomyocytes, normal human HaCaT keratinocytes
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Concentration:up to 100 μM
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Incubation Time:24 h, 48 h
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Result:Exhibited moderate cytotoxicity to H9c2 cells with an IC50 of 62.1 μM after 24 h incubation.
Exhibited moderate cytotoxicity to HaCaT cells with an IC50 of 56.5 μM after 24 h incubation.
Exhibited moderate cytotoxicity to H9c2 cells with an IC50 of 61.5 μM after 48 h incubation.
Exhibited moderate cytotoxicity to HaCaT cells with an IC50 of 57.1 μM after 48 h incubation.
Chemical Information
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CAS No. 25340-85-6
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Masse moléculaire 354.36
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Formule C20H18O6
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SMILES
O=C1C=2C(C(=O)C=3C1=C(O)C=C(O)C3)=CC(O)=C(/C=C/CCCC)C2O
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Averythrin Related Classifications
HY-187651 Related Classifications
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