BRD4 degrader-2
BRD4 degrader-2 (Compound JP-2-197) is a covalent monovalent molecular glue BRD4degrader that induces a ternary complex formation between BRD4 and RNF126. BRD4 degrader-2 targets RNF126 (E3 ligase) and degrades both the long and short isoforms of BRD4 in cells.
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- CAS No.: 3036530-43-2
- Formule: C34H33ClN6O4S
- Masse moléculaire:657.18
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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BRD4 |
Chemical Information
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CAS No. 3036530-43-2
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Masse moléculaire 657.18
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Formule C34H33ClN6O4S
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SMILES
ClC1=CC=C(C2=N[C@@H](CC(N3CCN(C(/C=C/C(C4=CC=C(OC)C=C4)=O)=O)CC3)=O)C5=NN=C(C)N5C6=C2C(C)=C(C)S6)C=C1
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
BRD4 degrader-2 Related Classifications
HY-163639 Related Classifications
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