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Cat. No.: HY-122192

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ICAM-1988

ICAM-1988 is a small molecule lymphocyte function-associated antigen-1 (LFA-1) antagonist that disrupts the LFA-1/ICAM-1 interaction and has anti-inflammatory activity.

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CAS No.: 444169-80-6
Formule: C₂₂H₂₂Cl₂N₄O₆S
Masse moléculaire:541.40

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Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (265 KB)

ICAM-1988 Chemical Structure

CAS No.: 444169-80-6

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Activité biologique

Description

ICAM-1988 is a small molecule lymphocyte function-associated antigen-1 (LFA-1) antagonist that disrupts the LFA-1/ICAM-1 interaction and has anti-inflammatory activity^[1].

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Chemical Information

CAS No. 444169-80-6
Masse moléculaire 541.40
Formule C₂₂H₂₂Cl₂N₄O₆S
SMILES

O=C([C@@H](NC(C1=C(C=C(C=C1Cl)CNC(/C=C/C2=CC=CO2)=O)Cl)=O)CNC([C@H]3NCSC3)=O)O
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

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Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (265 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Khojasteh SC, et al. Preclinical absorption, distribution, metabolism and excretion (ADME) characterization of ICAM1988, an LFA-1/ICAM antagonist, and its prodrug. Xenobiotica. 2008 Mar;38(3):340-52. [Content Brief]

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How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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ICAM-1988

Voir tous les produits spécifiques à Isoform Integrin

Activité biologique

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

ICAM-1988 Related Classifications

HY-122192 Related Classifications