444169-80-6
444169-80-6
Chemical Structure
ICAM-1988
- CAS No.: 444169-80-6
- Formula:C22H22Cl2N4O6S
- Molecular Weight:541.40
IUPAC Name: (S)-2-(2,6-dichloro-4-(((E)-3-(furan-2-yl)acrylamido)methyl)benzamido)-3-((R)-thiazolidine-4-carboxamido)propanoic acid
InChIKey: NKAQYHXMQJFUKQ-RYTMFUSVSA-N
SMILES: O=C([C@@H](NC(C1=C(C=C(C=C1Cl)CNC(/C=C/C2=CC=CO2)=O)Cl)=O)CNC([C@H]3NCSC3)=O)O
Biological Activity:
ICAM-1988 is a small molecule lymphocyte function-associated antigen-1 (LFA-1) antagonist that disrupts the LFA-1/ICAM-1 interaction and has anti-inflammatory activity[1].
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ICAM-1988 | ICAM-1988 is a small molecule lymphocyte function-associated antigen-1 (LFA-1) antagonist that disrupts the LFA-1/ICAM-1 interaction and has anti-inflammatory activity. |
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References
Keywords
