IL-17
Interleukin 17 (IL-17) is a family of pro-inflammatory cytokines. It consists of IL17A, IL17B, IL17C, IL17D, IL17E and IL17F. IL-17 is mainly produced by T helper 17 (Th17) cells. IL-17 can induce the release of certain chemokines (CXCL1, CXCL2, CXCL5, CXCL8, CXCL10), cytokines (IL-6, TNF-α, G-CSF, GM-CSF), matrix metalloproteinases (MMPs) (MMP1, MMP3, MMP9 and MMP13) and antimicrobial peptides (β-defensin and some S100 proteins) from mesenchymal and myeloid cells. IL-17 can also activate the nuclear factor (NF)-κB pathway. IL-17 is involved in various diseases such as autoimmune diseases, infection and cancer[1].
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IL-17 Recombinant Proteins (71)
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Inhibitors & Agonists (93)
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Recombinant Protein Expression Service
- Codon Optimization
- Gene Synthesis
- Construction of Expression Vector
- Strain Screening
- Protein Expression
- Purification & QC
- Protein Delivery
- Formule: Human
- Masse moléculaire: Sf9 insect cells
The EpCAM/TROP1 protein serves as an important homogeneous interacting molecule that promotes direct contact between intestinal epithelial cells (IEC) and intraepithelial lymphocytes (IEL) in the mucosal epithelium. This feature helps establish an immune barrier against mucosal infections. EpCAM/TROP1 Protein, Human (His-SUMO) is the recombinant human-derived EpCAM/TROP1 protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag.
